Zobrazeno 1 - 10
of 145
pro vyhledávání: '"S. Bisgaard"'
Autor:
Line S. Bisgaard, Pernille M. Christensen, Jeongah Oh, Federico Torta, Ernst-Martin Füchtbauer, Lars Bo Nielsen, Christina Christoffersen
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Aim: Apolipoprotein M (apoM) is mainly expressed in liver and in proximal tubular epithelial cells in the kidney. In plasma, apoM associates with HDL particles via a retained signal peptide and carries sphingosine-1-phosphate (S1P), a small bioactive
Externí odkaz:
https://doaj.org/article/c632fbff3ec14753b65f60b578dc6773
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Kidney disease affects more than 10% of the population, can be both acute and chronic, and is linked to other diseases such as cardiovascular disease, diabetes, and sepsis. Despite the detrimental consequences for patients, no good treatment options
Externí odkaz:
https://doaj.org/article/eb2d508cf59e4f039d4c34a511c46955
Autor:
Annemarie Aarup, Carsten H. Nielsen, Line S. Bisgaard, Ilze Bot, Henrik H. El-Ali, Andreas Kjaer, Lars B. Nielsen, Tanja X. Pedersen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract Atherosclerotic cardiovascular disease is a major complication of chronic kidney disease (CKD). CKD leads to uremia, which modulates the phenotype of aortic smooth muscle cells (SMCs). Phenotypic modulation of SMCs plays a key role in accele
Externí odkaz:
https://doaj.org/article/c01d0b83ed9c46878998b6f64f53187a
Autor:
Line S Bisgaard, Markus H Bosteen, Lisbeth N Fink, Charlotte M Sørensen, Alexander Rosendahl, Christina K Mogensen, Salka E Rasmussen, Bidda Rolin, Lars B Nielsen, Tanja X Pedersen
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168396 (2016)
Chronic kidney disease (CKD) leads to uremia. CKD is characterized by a gradual increase in kidney fibrosis and loss of kidney function, which is associated with a progressive increase in risk of atherosclerosis and cardiovascular death. To prevent p
Externí odkaz:
https://doaj.org/article/96e7d0a9e39041fb95411440e7e52ada
Autor:
Ida MH. Sørensen, Line S. Bisgaard, Sasha S. Bjergfelt, Ellen LF. Ballegaard, Tor Biering-Sørensen, Nino E. Landler, Tanja X. Pedersen, Klaus F. Kofoed, Theis Lange, Bo Feldt-Rasmussen, Susanne Bro, Christina Christoffersen
Publikováno v:
Atherosclerosis. 350
The relationship between chronic kidney disease (CKD) and cardiovascular events is well-established. Clinically recognised risk factors of cardiovascular disease cannot fully explain this association. The objective of the present cross-sectional stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d083a8c1b015726be2371b9e0424872c
https://pubmed.ncbi.nlm.nih.gov/35469655
https://pubmed.ncbi.nlm.nih.gov/35469655
Autor:
Lars Bo Nielsen, Ernst-Martin Füchtbauer, Line S. Bisgaard, Pernille M. Christensen, Christina Christoffersen
Publikováno v:
Nephrology Dialysis Transplantation. 36
Background and Aims Acute kidney injury is a severe disease with detrimental outcomes. The underlying ethiology is still elusive and besides dialysis, treatment options are poor. Apolipoprotein M (apoM) is mainly expressed in liver and in proximal tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f62678e543ec8e03a34daa119917e01
https://doi.org/10.1093/ndt/gfab084.0012
https://doi.org/10.1093/ndt/gfab084.0012
Autor:
Ida Maria Hjelm Soerensen, Sasha Saurbrey Bjergfelt, Susanne Bro, Bo Feldt-Rasmussen, Theis Lange, Christina Christoffersen, Tor Biering-Sørensen, Ellen Linnea Freese Ballegaard, Line S. Bisgaard, Klaus F. Kofoed, Nino Emanuel Landler
Publikováno v:
Nephrology Dialysis Transplantation. 36
Background and Aims The relation between chronic kidney disease and adverse cardiovascular events is well-established. It is also known that traditional risk factors of cardiovascular disease such as smoking, low-density lipoprotein (LDL) cholesterol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc777abb6db859c55512ee8435ada63c
https://doi.org/10.1093/ndt/gfab144.003
https://doi.org/10.1093/ndt/gfab144.003
Autor:
Marco Berrera, Marianne Lerbech Jensen, Martin Ebeling, Peter Hagedorn, Marianne R. Møller, Morten Lindow, Troels Koch, Henrik Frydenlund Hansen, Malene Pontoppidan, Heidi Rye Hudlebusch, Andreas Dieckmann, Tina S Bisgaard
Publikováno v:
Nucleic Acids Research
Hagedorn, P H, Pontoppidan, M, Bisgaard, T S, Berrera, M, Dieckmann, A, Ebeling, M, Møller, M R, Hudlebusch, H, Jensen, M L, Hansen, H F, Koch, T & Lindow, M 2018, ' Identifying and avoiding off-target effects of RNase H-dependent antisense oligonucleotides in mice ', Nucleic Acids Research, vol. 46, no. 11, pp. 5366-5380 . https://doi.org/10.1093/nar/gky397
Hagedorn, P H, Pontoppidan, M, Bisgaard, T S, Berrera, M, Dieckmann, A, Ebeling, M, Møller, M R, Hudlebusch, H, Jensen, M L, Hansen, H F, Koch, T & Lindow, M 2018, ' Identifying and avoiding off-target effects of RNase H-dependent antisense oligonucleotides in mice ', Nucleic Acids Research, vol. 46, no. 11, pp. 5366-5380 . https://doi.org/10.1093/nar/gky397
Antisense oligonucleotides that are dependent on RNase H for cleavage and subsequent degradation of complementary RNA are being developed as therapeutics. Besides the intended RNA target, such oligonucleotides may also cause degradation of unintended
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5852a56ae13fabda0113b0fcc3dafeb6
https://doi.org/10.1093/nar/gky397
https://doi.org/10.1093/nar/gky397
Publikováno v:
Acta Paediatrica. 107:1775-1780
Aim This study focused on children aged zero to six years with suspected single-dose paracetamol poisoning, which has not been investigated in Denmark. We evaluated the incidence of liver injuries and the use of activated charcoal and N-acetylcystein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e5b040f25a8eed6aa845d77a30b9a0
https://doi.org/10.1111/apa.14333
https://doi.org/10.1111/apa.14333
Autor:
Lars Bo Nielsen, Markus H. Bosteen, Tanja X. Pedersen, Eva Martha Madsen Svarrer, Marie Madsen, Christina Christoffersen, Line S. Bisgaard, Torben Martinussen
Publikováno v:
Atherosclerosis. 265:93-101
Background and aims Chronic kidney disease is characterized by uremia and causes premature death, partly due to accelerated atherosclerosis. Apolipoprotein (apo) M is a plasma carrier protein for the lipid sphingosine-1-phosphate (S1P). The Apom-S1P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c1f14532c40cc2c01aecc94813182b
https://doi.org/10.1016/j.atherosclerosis.2017.08.005
https://doi.org/10.1016/j.atherosclerosis.2017.08.005