Výsledky vyhledávání

Stem cell therapy for urinary stress incontinence

Autor: Silvia Hering, Steffen Hering, Rainer Marksteiner, S. Berjukow, Hannes Strasser, Georg Bartsch, Eva Margreiter

Publikováno v: Experimental Gerontology. 39:1259-1265

1. Introduction and rationaleThe increasing incidence in urinary incontinence (UI)with advancing age is directly correlated to spontaneousapoptosis of the muscle cells of the rhabdosphincter, thestriated urethral sphincter. As life expectancy of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::106d4bad34627dc55aaf0254184587bc
https://doi.org/10.1016/j.exger.2004.07.003

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On the fate of skeletal myoblasts in a cardiac environment: down-regulation of voltage-gated ion channels

Autor: Steffen Hering, Rainer Marksteiner, Guenther Laufer, S. Berjukow, G. Böck, Harald C. Ott, Eva Margreiter

Publikováno v: The Journal of Physiology. 558:793-805

We have analysed the voltage-gated ion channels and fusion competence of skeletal muscle myoblasts labelled with green fluorescent protein (GFP) and the membrane dye PKH transplanted into the infarcted myocardium of syngenic rats. After cell transpla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9990496fcf73766e298c975cd69b6e39
https://doi.org/10.1113/jphysiol.2003.060186

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Voltage-dependent acceleration of Cav 1.2 channel current decay by (+)- and (−)-isradipine

Autor: S. Berjukow, Steffen Hering

Publikováno v: British Journal of Pharmacology. 133:959-966

Inhibition of Ca(v)1.2 by antagonist 1,4 dihydropyridines (DHPs) is associated with a drug-induced acceleration of the calcium (Ca(2+)) channel current decay. This feature is contradictorily interpreted as open channel block or as drug-induced inacti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ae46bcf1bde7687d0ace066d33b143d
https://doi.org/10.1038/sj.bjp.0704181

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Structural Determinants of L-type Channel Activation in Segment IIS6 Revealed by a Retinal Disorder*

Autor: S. Berjukow, Eugen Timin, Steffen Hering, Marion A. Maw, Rainer Marksteiner, Michaela Kudrnac, Annette Hohaus, Stanislav Beyl

The mechanism of channel opening for voltage-gated calcium channels is poorly understood. The importance of a conserved isoleucine residue in the pore-lining segment IIS6 has recently been highlighted by functional analyses of a mutation (I745T) in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aab18a95c0a7975ef3fecb41bc0265d
https://europepmc.org/articles/PMC3189691/

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On the fate of skeletal myoblasts in a cardiac environment: down-regulation of voltage-gated ion channels

Autor: H C, Ott, S, Berjukow, R, Marksteiner, E, Margreiter, G, Böck, G, Laufer, S, Hering

Publikováno v: The Journal of physiology. 558(Pt 3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c9aad1f9eaae55165581cd0cc39b8fb8
https://pubmed.ncbi.nlm.nih.gov/15194742

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Inactivation determinants in segment IIIS6 of Ca(v)3.1

Autor: Rainer Marksteiner, Eva Margreiter, P Schurr, Steffen Hering, Edward Perez-Reyes, S. Berjukow

Publikováno v: The Journal of physiology. 537(Pt 1)

1. Low threshold, T-type, Ca(2+) channels of the Ca(v)3 family display the fastest inactivation kinetics among all voltage-gated Ca(2+) channels. The molecular inactivation determinants of this channel family are largely unknown. Here we investigate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69760681ae44f23a0b4289b87d9500cd
https://pubmed.ncbi.nlm.nih.gov/11711558

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Voltage-dependent acceleration of Ca(v)1.2 channel current decay by (+)- and (-)-isradipine

Autor: S, Berjukow, S, Hering

Publikováno v: British journal of pharmacology. 133(7)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3173b7a21667016a56e7d0b4518bc2da
https://pubmed.ncbi.nlm.nih.gov/11487504

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Molecular mechanism of calcium channel block by isradipine. Role of a drug-induced inactivated channel conformation

Autor: S, Berjukow, R, Marksteiner, F, Gapp, M J, Sinnegger, S, Hering

Publikováno v: The Journal of biological chemistry. 275(29)

The role of the inactivated channel conformation in the molecular mechanism of Ca(2+) channel block by the 1,4-dihydropyridine (DHP) (+)-isradipine was analyzed in L-type channel constructs (alpha(1Lc); Berjukow, S., Gapp, F., Aczel, S., Sinnegger, M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5085850b4882aad7acd2235a8a7b4330
https://pubmed.ncbi.nlm.nih.gov/10766758

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