Zobrazeno 1 - 10
of 37
pro vyhledávání: '"S. B. Kanner"'
Autor:
Martin J. Humphries, R. G. Wickremasinghe, S. B. Kanner, I. E. Collins, N. Amft, Tony Ng, K. E. Nye, W. J. W. Morrow, D. D'cruz
Publikováno v:
Lupus. 8:39-51
Objective: To establish the relationship between T cell responses to integrin coreceptor stimulation and B cell hyperreactivity as measured by pathologic autoantibody production.Methods: Peripheral blood mononuclear cells from 42 patients with SLE ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c06c6af8b67c36691c47052f2b08fe
https://doi.org/10.1191/096120399678847371
https://doi.org/10.1191/096120399678847371
Publikováno v:
The Journal of Immunology. 154:3180-3193
The CD28 molecule expressed on the surface of T cells plays a pivotal role in transducing costimulatory signals necessary for cell activation. CD28 coligation enhances tyrosine phosphorylation and phosphoinositol 3-kinase association in responsive ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de2f1f88ba76f9650bfa8699f87ab583
https://doi.org/10.4049/jimmunol.154.7.3180
https://doi.org/10.4049/jimmunol.154.7.3180
Autor:
S B Kanner, O K Haffar
Publikováno v:
The Journal of Immunology. 154:2996-3005
One consequence of HIV type 1 (HIV-1) infection is the gradual loss of responsiveness of T lymphocytes to Ags both in vitro and in vivo. It has been suggested that the underlying mechanism that contributes to this T cell dysfunction before CD4+ cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fd661e08676d357933bb66f06470408
https://doi.org/10.4049/jimmunol.154.6.2996
https://doi.org/10.4049/jimmunol.154.6.2996
Autor:
D C Flynn, Michael D. Schaller, Amy H. Bouton, Scott A. Weed, Albert B. Reynolds, S B Kanner, J T Parsons
Publikováno v:
Oncogene. 33(37)
By the mid 1980's, it was clear that the transforming activity of oncogenic Src was linked to the activity of its tyrosine kinase domain and attention turned to identifying substrates, the putative next level of control in the pathway to transformati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f041b0d932a70b0cebe08b991a2f055f
https://pubmed.ncbi.nlm.nih.gov/24121272
https://pubmed.ncbi.nlm.nih.gov/24121272
Publikováno v:
The Journal of Immunology. 150:5289-5298
MHC class II-positive T cells are found in tissues involved in autoimmune and infectious disorders. Because stimulation of class II molecules by mAb or bacterial superantigens induces protein tyrosine phosphorylation through activation of PTK3 in T c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56e3aba95bd69697bd4a3d2d8a625fd1
https://doi.org/10.4049/jimmunol.150.12.5289
https://doi.org/10.4049/jimmunol.150.12.5289
Publikováno v:
The Journal of Immunology. 149:3482-3488
Bacterial enterotoxin superantigens bind directly to HLA class II molecules (HLA-DR) expressed on both APC and activated human T cells, and simultaneously bind to certain V beta chains of the TCR. In this report, we compared early T cell signaling ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4370bec3511e43075a6579bd88346645
https://doi.org/10.4049/jimmunol.149.11.3482
https://doi.org/10.4049/jimmunol.149.11.3482
Publikováno v:
Molecular and Cellular Biology. 11:5113-5124
Transformation of cells by the src oncogene results in elevated tyrosine phosphorylation of two related proteins, p80 and p85 (p80/85). Immunostaining with specific monoclonal antibodies revealed a striking change of subcellular localization of p80/8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e65002acb2b8712d7b7df91ea868a747
https://doi.org/10.1128/mcb.11.10.5113
https://doi.org/10.1128/mcb.11.10.5113
Publikováno v:
ResearcherID
Transformation of chicken embryo cells with the tyrosine kinase oncogene src results in the tyrosine phosphorylation of numerous cellular proteins. We have recently generated monoclonal antibodies to individual tyrosine phosphorylated cellular src su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a10c69767d6e39e3bd14cc74dde905
https://doi.org/10.1002/j.1460-2075.1991.tb07693.x
https://doi.org/10.1002/j.1460-2075.1991.tb07693.x
Publikováno v:
Molecular and Cellular Biology. 11:945-953
GTPase-activating protein (GAP) is a cytosolic protein that stimulates the rate of hydrolysis of GTP (GTP to GDP) bound to normal p21ras, but does not catalyze the hydrolysis of GTP bound to oncogenic, activated forms of the ras protein. Transformati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e70bc571850daf860ff914039bdb797b
https://doi.org/10.1128/mcb.11.2.945
https://doi.org/10.1128/mcb.11.2.945
Publikováno v:
Molecular and Cellular Biology. 11:945-953
GTPase-activating protein (GAP) is a cytosolic protein that stimulates the rate of hydrolysis of GTP (GTP to GDP) bound to normal p21ras, but does not catalyze the hydrolysis of GTP bound to oncogenic, activated forms of the ras protein. Transformati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd78d9025dd19fc62d7aae593dbbab1
https://doi.org/10.1128/mcb.11.2.945-953.1991
https://doi.org/10.1128/mcb.11.2.945-953.1991