Zobrazeno 1 - 10
of 19
pro vyhledávání: '"S. B. Kalindjian"'
Autor:
Malcolm Maden, Maria B. Goncalves, M. Dogruel, S. B. Kalindjian, Earl Clarke, Sarah A. Thomas, Christopher I. Jarvis, Jonathan Corcoran
Publikováno v:
European Journal of Neuroscience. 32:1246-1255
Alzheimer's disease (AD) is characterized by amyloid-β (Aβ) deposition in the brain, neuronal cell loss and cognitive decline. We show here that retinoic acid receptor (RAR)α signalling in vitro can prevent both intracellular and extracellular Aβ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::843ea2cbc8006b3d675401799ef83b52
https://doi.org/10.1111/j.1460-9568.2010.07426.x
https://doi.org/10.1111/j.1460-9568.2010.07426.x
Publikováno v:
British Journal of Pharmacology. 151:1352-1367
Background and purpose: Several studies using radioligand binding assays, have shown that measurement of thermodynamic parameters can allow discrimination of agonists and antagonists (Weiland et al., 1979; Borea et al., 1996a). Here we investigate wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::740ce441e8103d717b63735804b58a7b
https://doi.org/10.1038/sj.bjp.0707355
https://doi.org/10.1038/sj.bjp.0707355
Autor:
Nigel P. Shankley, Matthew J. Tozer, S B Kalindjian, Elaine Anne Harper, Michael John Pether, G. F. Watt
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 9:1825-1830
Histamine was converted to a selective histamine H3-receptor antagonist by capping the primary amine with 2-naphthalenesulfonyl chloride. Higher receptor affinity and lower variability in the data from the various bioassays were achieved with the 2-n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eae0785213b069819d6f8c282bbcf0d1
https://doi.org/10.1016/s0960-894x(99)00272-3
https://doi.org/10.1016/s0960-894x(99)00272-3
Autor:
S. B. Kalindjian, R. A. G. Smith
Publikováno v:
ChemInform. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c94c0bbd37822124336f605e83a06b5
https://doi.org/10.1002/chin.199220051
https://doi.org/10.1002/chin.199220051
Publikováno v:
ChemInform. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea9f309ed61adcf335adc4ef8a3e0245
https://doi.org/10.1002/chin.199544225
https://doi.org/10.1002/chin.199544225
Publikováno v:
ChemInform. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32351ddf3181ba28a591a50b2b99907b
https://doi.org/10.1002/chin.199544226
https://doi.org/10.1002/chin.199544226
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f787be94a90d26e5b0972a295d78180b
https://doi.org/10.1002/chin.199739226
https://doi.org/10.1002/chin.199739226
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13df9a685d1d705d7581d8a86760a386
https://doi.org/10.1002/chin.199735190
https://doi.org/10.1002/chin.199735190
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8caedf416c8c579eafa11d2e2a1ff55
https://doi.org/10.1002/chin.199746052
https://doi.org/10.1002/chin.199746052