Zobrazeno 1 - 10
of 186
pro vyhledávání: '"S. Ashwell"'
Publikováno v:
BMC Musculoskeletal Disorders, Vol 19, Iss 1, Pp 1-8 (2018)
Abstract Background Osteoarthritis is a degradative joint disease found in humans and commercial swine which can develop from a number of factors, including prior joint trauma. An impact injury model was developed to deliver in vitro loads to disease
Externí odkaz:
https://doaj.org/article/e18c1c216f4f439c98dc7b37859c3a8a
Autor:
Jeremy T. Howard, Melissa S. Ashwell, Ronald E. Baynes, James D. Brooks, James L. Yeatts, Christian Maltecca
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Identifying individual genetic variation in drug metabolism pathways is of importance not only in livestock, but also in humans in order to provide the ultimate goal of giving the right drug at the right dose at the right time. Our objective
Externí odkaz:
https://doaj.org/article/23b23d05a48845e98efd4e4f76751f13
Autor:
Jyothi Thittamranahalli Kariyappa, Simone Zanoni, Andre Bongers, Lydia Tong, Ken W. S. Ashwell
Publikováno v:
Journal of Comparative Neurology. 530:2188-2214
The diversity of the diprotodontids provides an excellent opportunity to study how a basic marsupial cortical plan has been modified for the needs of the mammals living in different habitats. Very little is known about the connections of the cerebral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c02f33e58e3d008367dbd5935818afdb
https://doi.org/10.1002/cne.25328
https://doi.org/10.1002/cne.25328
Autor:
Jeremy T. Howard, Melissa S. Ashwell, Ronald E. Baynes, James D. Brooks, James L. Yeatts, Christian Maltecca
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
In livestock, the regulation of drugs used to treat livestock has received increased attention and it is currently unknown how much of the phenotypic variation in drug metabolism is due to the genetics of an animal. Therefore, the objective of the st
Externí odkaz:
https://doaj.org/article/a452fdd441bd472d8b4846b6ceba7cdb
Autor:
Gregory S Berns, Ken W S Ashwell
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0168993 (2017)
The last known Tasmanian tiger (Thylacinus cynocephalus)-aka the thylacine-died in 1936. Because its natural behavior was never scientifically documented, we are left to infer aspects of its behavior from museum specimens and historical recollections
Externí odkaz:
https://doaj.org/article/6830a86610104db98043776e83bc53ed
Autor:
Jyothi Thittamranahalli Kariyappa, Simone Zanoni, Andre Bongers, Lydia Tong, Ken W. S. Ashwell
Publikováno v:
Journal of Comparative Neurology. 530
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15f33c3748d6e19d26f6e55d28794948
https://doi.org/10.1002/cne.25377
https://doi.org/10.1002/cne.25377
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Jian Lin, M. Katz, S. Ashwell, A.M. Campbell, K.J. Barr, Mark T. Kershaw, Wei Lu, D. Walker, Zhongguo Wang, Angela V. Toms, L. Yao, A. Clarke, R.B. Diebold, H.R. Josephine, Deepali Gotur, A. Ericsson, Christopher J. Dinsmore, G.R. Gustafson, Caravella Justin Andrew, Jennifer Castro
Publikováno v:
Journal of Medicinal Chemistry. 63:1612-1623
Inhibition of mutant IDH1 is being evaluated clinically as a treatment option for oncology. Here we describe the structure-based design and optimization of quinoline lead compounds to identify FT-2102, a potent, orally bioavailable, brain penetrant,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0965a9edfde187ce8dfcfe433ff8a562
https://doi.org/10.1021/acs.jmedchem.9b01423
https://doi.org/10.1021/acs.jmedchem.9b01423
Autor:
Ken W. S. Ashwell
Publikováno v:
Encyclopedia of Animal Cognition and Behavior ISBN: 9783319478296
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c3ecb93653fed9026a0dfed185fac83
https://doi.org/10.1007/978-3-319-55065-7_2066
https://doi.org/10.1007/978-3-319-55065-7_2066
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137830 (2015)
Characterizing the variability in transcript levels across breeds and sex in swine for genes that play a role in drug metabolism may shed light on breed and sex differences in drug metabolism. The objective of the study is to determine if there is he
Externí odkaz:
https://doaj.org/article/1b24fc854e95457aa1d9cb16bed76fca