Zobrazeno 1 - 10
of 75
pro vyhledávání: '"S. Alex Mitsialis"'
Autor:
Junwen Han, Gu Li, Minmin Hou, Julie Ng, Min-Young Kwon, Kevin Xiong, Xiaoliang Liang, Elizabeth Taglauer, Yuanyuan Shi, S. Alex Mitsialis, Stella Kourembanas, Souheil El-Chemaly, James A. Lederer, Ivan O. Rosas, Mark A. Perrella, Xiaoli Liu
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2021)
Abstract Background Acute lung injury (ALI) is a common lung disorder that affects millions of people every year. The infiltration of inflammatory cells into the lungs and death of the alveolar epithelial cells are key factors to trigger a pathologic
Externí odkaz:
https://doaj.org/article/1b5a4b7e6e4f42eeaf691adb94b11b6f
Autor:
Monica Reis, Gareth R. Willis, Angeles Fernandez-Gonzalez, Vincent Yeung, Elizabeth Taglauer, Margaret Magaletta, Teagan Parsons, Alan Derr, Xianlan Liu, Rene Maehr, Stella Kourembanas, S. Alex Mitsialis
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Treating premature infants with high oxygen is a routine intervention in the context of neonatal intensive care. Unfortunately, the increase in survival rates is associated with various detrimental sequalae of hyperoxia exposure, most notably broncho
Externí odkaz:
https://doaj.org/article/48c96b5a14204a3498f375549593d072
Autor:
Angeles Fernandez-Gonzalez, Gareth R. Willis, Vincent Yeung, Monica Reis, Xianlan Liu, S. Alex Mitsialis, Stella Kourembanas
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Despite major advances in neonatal intensive care, infants born at extremely low birth weight still face an increased risk for chronic illness that may persist into adulthood. Pulmonary, retinal, and neurocognitive morbidities associated with preterm
Externí odkaz:
https://doaj.org/article/0d6260c31682493faaecf86ef963cd63
Autor:
Gareth R. Willis, Angeles Fernandez-Gonzalez, Monica Reis, Vincent Yeung, Xianlan Liu, Maria Ericsson, Nick A. Andrews, S. Alex Mitsialis, Stella Kourembanas
Publikováno v:
Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)
Early administration of mesenchymal stromal cell (MSC)-derived small extracellular vesicles (MEx) has shown considerable promise in experimental models of bronchopulmonary dysplasia (BPD). However, the ability of MEx to reverse the long-term pulmonar
Externí odkaz:
https://doaj.org/article/ba84d02555684ea1b4cff5802b9232f3
Autor:
Kenneth W. Witwer, Bas W.M. Van Balkom, Stefania Bruno, Andre Choo, Massimo Dominici, Mario Gimona, Andrew F. Hill, Dominique De Kleijn, Mickey Koh, Ruenn Chai Lai, S. Alex Mitsialis, Luis A. Ortiz, Eva Rohde, Takashi Asada, Wei Seong Toh, Daniel J. Weiss, Lei Zheng, Bernd Giebel, Sai Kiang Lim
Publikováno v:
Journal of Extracellular Vesicles, Vol 8, Iss 1 (2019)
Small extracellular vesicles (sEVs) from mesenchymal stromal/stem cells (MSCs) are transiting rapidly towards clinical applications. However, discrepancies and controversies about the biology, functions, and potency of MSC-sEVs have arisen due to sev
Externí odkaz:
https://doaj.org/article/6a24d06e7d914f599d1674a7bb00f74e
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 4 (2017)
Exosomes are defined as submicron (30–150 nm), lipid bilayer-enclosed extracellular vesicles (EVs), specifically generated by the late endosomal compartment through fusion of multivesicular bodies with the plasma membrane. Produced by almost all ce
Externí odkaz:
https://doaj.org/article/4e407acba1814dcf8ec038caca7c0985
Autor:
Alison N. Abele, Elizabeth S. Taglauer, Maricar Almeda, Noah Wilson, Abigail Abikoye, Gregory J. Seedorf, S. Alex Mitsialis, Stella Kourembanas, Steven H. Abman
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Antenatal stressors such as chorioamnionitis (CA) increase the risk for bronchopulmonary dysplasia (BPD). Studies have shown that experimental BPD can be ameliorated by postnatal treatment with mesenchymal stromal cell-derived extracellular vesicles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d0112fa78ae8a786e8c98a385a0275
https://doi.org/10.1152/ajplung.00329.2021
https://doi.org/10.1152/ajplung.00329.2021
Autor:
Angeles Fernandez-Gonzalez, S. Alex Mitsialis, Lawrence S. Prince, Xianlan Liu, Vincent Yeung, Stella Kourembanas, Gareth R. Willis, Elizabeth S. Taglauer, Monica Reis
Publikováno v:
Am J Respir Cell Mol Biol
In preeclamptic pregnancies, a variety of intrauterine alterations lead to abnormal placentation, release of inflammatory and/or antiangiogenic factors, and subsequent fetal growth restriction with significant potential to cause a primary insult to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e46b64e94fcdb49b88279de83d19968
https://doi.org/10.1165/rcmb.2021-0307oc
https://doi.org/10.1165/rcmb.2021-0307oc
Autor:
Xianlan Liu, Angeles Fernandez-Gonzalez, Ali Hashemi Gheinani, Elizabeth S. Taglauer, Gareth R. Willis, S. Alex Mitsialis, Eric Haas, Stella Kourembanas, Maria Ericsson, Monica Reis, Vincent Yeung
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 204:1418-1432
Rationale: Mesenchymal stem/stromal cell (MSC)-small extracellular vesicle (MEx) treatment has shown promise in models of neonatal lung injury. The molecular mechanisms by which MEx afford benefici...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be14c1732983a29179a327fa2bba496d
https://doi.org/10.1164/rccm.202102-0329oc
https://doi.org/10.1164/rccm.202102-0329oc
Autor:
Eleni Delavogia, Dimitrios P Ntentakis, John A Cortinas, Angeles Fernandez-Gonzalez, S Alex Mitsialis, Stella Kourembanas
Publikováno v:
Stem cells (Dayton, Ohio). 40(11)
Over the past decades, substantial advances in neonatal medical care have increased the survival of extremely premature infants. However, there continues to be significant morbidity associated with preterm birth with common complications including br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a0d87378e56c42d1bf85140f63e55b
https://pubmed.ncbi.nlm.nih.gov/36044737
https://pubmed.ncbi.nlm.nih.gov/36044737