Zobrazeno 1 - 10
of 722
pro vyhledávání: '"S. ANSORGE"'
Autor:
Elizabeth A. Pekarskaya, Emma S. Holt, Jay A. Gingrich, Mark S. Ansorge, Jonathan A. Javitch, Sarah E. Canetta
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Depression and anxiety, two of the most common mental health disorders, share common symptoms and treatments. Most pharmacological agents available to treat these disorders target monoamine systems. Currently, finding the most effective trea
Externí odkaz:
https://doaj.org/article/dacd9ec969a649caa396d38a5bf9a485
Autor:
Darshini Mahadevia, Rinki Saha, Alessia Manganaro, Nao Chuhma, Annette Ziolkowski-Blake, Ashlea A. Morgan, Dani Dumitriu, Stephen Rayport, Mark S. Ansorge
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The authors show that terminal activity of dopaminergic neurons selectively projecting from the ventral tegmental area to the lateral septum is sufficient for promoting aggression and necessary for establishing baseline aggression in mice.
Externí odkaz:
https://doaj.org/article/bedb5a8b28ab4e4cadccee6c0020bd40
Autor:
Ashlea A. Morgan, Nuno D. Alves, Gregory S. Stevens, Tamanna T. Yeasmin, Alexandra Mackay, Saige Power, Derya Sargin, Carla Hanna, Arwa L. Adib, Annette Ziolkowski-Blake, Evelyn K. Lambe, Mark S. Ansorge
Publikováno v:
bioRxiv
The medial prefrontal cortex (mPFC) regulates cognitive flexibility and emotional behavior. Neurons that release serotonin project to the mPFC, and serotonergic drugs influence emotion and cognition. Yet, the specific roles of endogenous serotonin re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a73827ec9515913085af7e13d7e84b
https://europepmc.org/articles/PMC10081203/
https://europepmc.org/articles/PMC10081203/
Autor:
Giulia Zanni, Milenna Van Dijk, Martha Caffrey Cagliostro, Gregory S. Stevens, Nicolò Pini, Ariel L. Rose, Alexander L. Kesin, Claudia Lugo-Candelas, Priscila Dib Goncalves, Alexandra S. MacKay, Praveen Kulkarni, Craig F. Ferris, Myrna M. Weissman, Ardesheer Talati, Mark S. Ansorge, Jay A. Gingrich
Serotonin shapes brain structure and function during early development across phylogenetically diverse species. In mice and humans, perinatal SSRI exposure produces brain alterations and increases anxiety/depression-related behaviors in the offspring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0b94f90446bb93ad4cf4ed5caa7bf3e
https://doi.org/10.1101/2023.03.01.23286641
https://doi.org/10.1101/2023.03.01.23286641
Autor:
Anne Teissier, Alexei Chemiakine, Benjamin Inbar, Sneha Bagchi, Russell S. Ray, Richard D. Palmiter, Susan M. Dymecki, Holly Moore, Mark S. Ansorge
Publikováno v:
Cell Reports, Vol 13, Iss 9, Pp 1965-1976 (2015)
Despite the well-established role of serotonin signaling in mood regulation, causal relationships between serotonergic neuronal activity and behavior remain poorly understood. Using a pharmacogenetic approach, we find that selectively increasing sero
Externí odkaz:
https://doaj.org/article/6e2d4e5c13d842b1854e3bcf1134a308
Autor:
Cátia M. Teixeira, Mark S. Ansorge, John F. Smiley, Robert H. Edwards, Edenia C. Menezes, Nao Chuhma, Relish Shah, Cynthia Bleiwas, Francisco X. Castellanos, Stephen Rayport, Catarina Cunha, Rebecca P. Seal
Publikováno v:
Molecular psychiatry
Serotonin and dopamine are associated with multiple psychiatric disorders. How they interact during development to affect subsequent behavior remains unknown. Knockout of the serotonin transporter or postnatal blockade with selective serotonin reupta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70b52d3c8dbb5da59ae3a3950d00019b
https://doi.org/10.1038/s41380-020-0763-z
https://doi.org/10.1038/s41380-020-0763-z
Autor:
Salma Begum, Edward Laufer, David T. Breault, Juilee Rege, William E. Rainey, Matthew Taylor, Celso E. Gomez-Sanchez, Emily C. Frucci, Mark S. Ansorge, Matthew Ullenbruch
Publikováno v:
Journal of Clinical Investigation. 130:83-93
The mineralocorticoid aldosterone is produced in the adrenal zona glomerulosa (ZG) under the control of the renin–angiotensin II (AngII) system. Primary aldosteronism (PA) results from renin-independent production of aldosterone and is a common cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b927db8f4f05673234ccfd15e969f70b
https://doi.org/10.1172/jci127429
https://doi.org/10.1172/jci127429
Autor:
Peter Šebej, Yekaterina Kovalyova, Dalibor Sames, David Sulzer, Christopher Hwu, Iva Dincheva, Mark S. Ansorge, Niko G. Gubernator, Adam Henke, Matthew Dunn, Dominik Dreier
Publikováno v:
ACS Chemical Neuroscience. 9:925-934
Ongoing efforts in our laboratories focus on design of optical reporters known as fluorescent false neurotransmitters (FFNs) that enable the visualization of uptake into, packaging within, and release from individual monoaminergic neurons and presyna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10a4269537119327265bd84d9b1660b9
https://doi.org/10.1021/acschemneuro.7b00320
https://doi.org/10.1021/acschemneuro.7b00320
Autor:
Alvaro L. Garcia-Garcia, Mark S. Ansorge, Alex Dranovsky, Nesha S. Burghardt, Sarah E. Canetta, J M Stujenske, E D Leonardo
Publikováno v:
Molecular psychiatry
Serotonin (5-HT) neurons project from the raphe nuclei throughout the brain where they act to maintain homeostasis. Here, we study 5-HT inputs into the bed nucleus of the stria terminalis (BNST), a major subdivision of the extended amygdala that has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::855b6cc5e41e6206e5211a756a145ac8
http://europepmc.org/articles/PMC5794659
http://europepmc.org/articles/PMC5794659
Autor:
Martha K. Caffrey Cagliostro, Alan S. Brown, Mark S. Ansorge, Myrna M. Weissman, Jay A. Gingrich, Deepika Suri, Darshini Mahadevia, Cátia M. Teixeira, Heli Malm, Andre Sourander
Publikováno v:
Birth Defects Research. 109:924-932
Development passes through sensitive periods, during which plasticity allows for genetic and environmental factors to exert indelible influence on the maturation of the organism. In the context of central nervous system (CNS) development, such sensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7d73156031764d4294a6d480be3671
https://doi.org/10.1002/bdr2.1085
https://doi.org/10.1002/bdr2.1085