Zobrazeno 1 - 10
of 13
pro vyhledávání: '"S. A. Silbaugh"'
Publikováno v:
Neuropeptides. 28:35-42
We examined the relationship between airway obstruction and plasma extravasation produced by the intravenous administration of the selective NK1 receptor agonist [Sar9, Met(O2)11]-substance P(SP). Conscious guinea-pigs were injected with Evans' blue
Autor:
C. R. Roman, Michael J. Sofia, Baldwin Rf, Sandra L. Cockerham, S. A. Silbaugh, K. Nelson, Larry L. Froelich, P. Marder, Floreancig Paul Edward, Stephen Richard Baker, P. W. Stengel, Jason Scott Sawyer, S. M. Spaethe, D. L. Saussy, J. H. Fleisch, W. T. Jackson, Bach Nicholas J
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461374305
Leukotriene B4 (LTB4) has been implicated as a key pro-inflammatory mediator in human diseases such as asthma, inflammatory bowel disease, psoriasis and arthritis (1). LTB4’s role in human disease is supported by the fact that via G-protein coupled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1ac724edeb191b804e43ef5b753a2f4
https://doi.org/10.1007/978-1-4615-5325-0_51
https://doi.org/10.1007/978-1-4615-5325-0_51
Autor:
M J, Sofia, P, Floreancig, N, Bach, S R, Baker, K, Nelson, J S, Sawyer, R, Baldwin, S L, Cockerham, J H, Fleisch, L L, Froelich, W T, Jackson, P, Marder, C R, Roman, D L, Saussy, S A, Silbaugh, S M, Spaethe, P W, Stengel
Publikováno v:
Advances in experimental medicine and biology.
Publikováno v:
Europe PubMed Central
Postmortem pulmonary gas trapping was investigated as an index of in vivo airway obstruction following methacholine inhalation in four different rodent species. Male guinea pigs (Hartley), hamsters (golden Syrian), mice (A/J, BALB/c, and ICR), and ra
Autor:
Baldwin Rf, P. W. Stengel, Sandra L. Cockerham, D. L. Saussy, Larry L. Froelich, Michael J. Sofia, Floreancig Paul Edward, P. Marder, S. A. Silbaugh, Jason Scott Sawyer
Publikováno v:
Journal of medicinal chemistry. 36(24)
Publikováno v:
Agents and actions. Supplements. 34
Male Hartley guinea pigs were treated with the enkephalinase inhibitor thiorphan by inhaled or intravenous administration routes and potentiation of substance P-induced airway obstruction examined. Inhaled thiorphan was several thousand times more po
Autor:
J. L. Mauderly, S. A. Silbaugh
Publikováno v:
Journal of Toxicology and Environmental Health. 18:133-141
Four groups of 20 guinea pigs were sequentially exposed by inhalation to either air followed by sulfuric acid aerosol, ozone followed by sulfuric acid aerosol, ozone followed by air, or air followed by air to determine whether ozone preexposure sensi
Autor:
J. L. Mauderly, S. A. Silbaugh
Publikováno v:
Journal of applied physiology: respiratory, environmental and exercise physiology. 56(6)
Tidal volume measured by the barometric method is very sensitive to increases in compression and expansion of alveolar gas, such as would be expected to occur during airway narrowing or closure. By comparing a barometric method tidal volume signal (V
Publikováno v:
Laboratory animal science. 37(3)
Autor:
P W, Stengel, S A, Silbaugh
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 248(3)
Conscious guinea pigs that were briefly exposed to an aerosol of A23187 developed a prolonged airway constrictive response that lasted at least 60 min. Cumulative i.v. doses of various drugs were given and reversal of dynamic compliance (Cdyn) examin