Zobrazeno 1 - 10
of 137
pro vyhledávání: '"S. A. Shchelkunov"'
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 27, Iss 6, Pp 712-718 (2023)
The monkeypox epidemic, which became unusually widespread among humans in 2022, has brought awareness about the necessity of smallpox vaccination of patients in the risk groups. The modern smallpox vaccine variants are introduced either intramuscular
Externí odkaz:
https://doaj.org/article/aff4ada3006043bbad8155875dba2ce5
Autor:
S. N. Shchelkunov, S. N. Yakubitskiy, A. E. Nesterov, I. V. Kolosova, A. A. Sergeev, А. V. Zaykovskaya, A. S. Kabanov, Е. A. Nechaeva, M. P. Bogryantseva, S. V. Usova, N. S. Kutserubova, T. V. Tregubchak, E. V. Gavrilova, R. A. Maksyutov
Publikováno v:
Эпидемиология и вакцинопрофилактика, Vol 21, Iss 6, Pp 34-47 (2023)
Relevance. The epidemiological situation in the world is characterized by an increase in the incidence of orthopoxvirus infections in humans and animals. In this regard, it is necessary to develop new safe vaccines against these infections.Aim. Condu
Externí odkaz:
https://doaj.org/article/96923c43cb564af583c30823e608c87b
Autor:
R. A. Maksyutov, S. N. Yakubitskiy, I. V. Kolosova, T. V. Tregubchak, A. N. Shvalov, E. V. Gavrilova, S. N. Shchelkunov
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 26, Iss 4, Pp 394-401 (2022)
Due to cessation of mass smallpox vaccination in 1980, the collective immunity of humans against orthopoxvirus infections has virtually been lost. Therefore, the risk of spreading zoonotic human orthopoxvirus infections caused by monkeypox and cowpox
Externí odkaz:
https://doaj.org/article/b529cf34cabf40fab9e8c17966d444e9
Publikováno v:
Медицинская иммунология, Vol 24, Iss 1, Pp 201-206 (2022)
At the present time, vast majority of human population lacks immunity against orthopoxvirus infections caused by variola (smallpox), monkeypox, cowpox, or buffalopox viruses. More and more mass outbreaks of orthopoxvirus infections are yearly registe
Externí odkaz:
https://doaj.org/article/9bae215419d34c8ba23ef1d4dfe9c5d4
Publikováno v:
Инфекция и иммунитет, Vol 11, Iss 6, Pp 1167-1172 (2022)
Smallpox eradication and lack of adequate animal model for smallpox infection underlies a necessity to assess immunogenic and protective properties of genetic engineering-created live attenuated smallpox vaccines in several animal models of orthopoxv
Externí odkaz:
https://doaj.org/article/17d2e853962c420fbeea6584152ca8e6
Autor:
S. N. Shchelkunov, T. V. Bauer, S. N. Yakubitskiy, A. A. Sergeev, A. S. Kabanov, S. A. Pyankov
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 25, Iss 2, Pp 139-146 (2021)
Vaccination is the most simple and reliable approach of protection to virus infections. The most effective agents are live vaccines, usually low-virulence organisms for humans and closely related to pathogenic viruses or attenuated as a result of mut
Externí odkaz:
https://doaj.org/article/3bc0db724caf416fa1ac6bc82b81f403
Autor:
S. N. Shchelkunov, A. A. Sergeev, A. S. Kabanov, S. N. Yakubitskyi, T. V. Bauer, S. A. Pyankov
Publikováno v:
Инфекция и иммунитет, Vol 11, Iss 2, Pp 357-364 (2021)
Vaccinia virus had played a key role in the global smallpox eradication. However, in case of mass vaccination with various Vaccinia virus strains severe side effects were revealed sometimes ending up with lethal outcomes, especially in immunocompromi
Externí odkaz:
https://doaj.org/article/5661108ca47949eabc4a92db7f760dab
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 24, Iss 3, Pp 239-243 (2020)
Tumor necrosis factor (TNF) is one among the key cytokines that mediate the immune system to protect humans against viral infections. Throughout evolution, anthropogenic Variola virus (VARV) has developed effective mechanisms to overcome human defens
Externí odkaz:
https://doaj.org/article/7f73e38844824e1c9f6c57c1d0208075
Publikováno v:
Медицинская иммунология, Vol 22, Iss 2, Pp 371-378 (2020)
The problems of oncological disease treatment are considered relevant and timely issues of the current research programs. Since monotherapy is increasingly clear to be less effective than combination therapy, the novel studies seek for advancement of
Externí odkaz:
https://doaj.org/article/5ae29a537c5e4cbda7a097131bc4b54b
Autor:
S. N. Shchelkunov, G. A. Shchelkunova
Publikováno v:
Вопросы вирусологии, Vol 64, Iss 5, Pp 206-214 (2019)
The review contains a brief analysis of the results of investigations conducted during 40 years after smallpox eradication and directed to study genomic organization and evolution of variola virus (VARV) and development of modern diagnostics, vaccine
Externí odkaz:
https://doaj.org/article/0a66fc2bdba14ac08d1902b5da46fb3e