Zobrazeno 1 - 10
of 33
pro vyhledávání: '"S. A. Moyes"'
Publikováno v:
The journal of nutrition, health & aging. 27:67-74
Objectives To investigate associations between nutrition risk (determined by SCREEN-II) and malnutrition (diagnosed by the GLIM criteria) with five-year mortality in Māori and non-Māori of advanced age. Design A longitudinal cohort study. Setting B
Publikováno v:
Progress in Histochemistry and Cytochemistry. 46:185-252
Uptake of ingested microparticles into small intestinal tissues and on to secondary organs has moved from being an anecdotal phenomenon to a recognised and quantifiable process, which is relevant to risk assessment of accidental exposure, treatment o
Publikováno v:
Journal of Anatomy. 217:740-754
Caco-2 cells form an enterocyte-like monolayer that has been used to explore small intestinal microparticle uptake. They are a useful functional model for the investigation of in vivo drug delivery systems and the uptake of particulate environmental
Publikováno v:
International Journal of Pharmaceutics. 335:79-89
The aim of this study is to compare microparticle uptake in animals of different ages, gender and species and at different time points. The 2 μm latex/ in vivo in situ model uses the observation of animal responses or post-mortem changes and also pa
Autor:
B R Maziak, Marianne Brüggemann, Rizgar A. Mageed, C.G. Mackworth-Young, S P Moyes, Ian J. Harmer, S.L. Wynn
Publikováno v:
Clinical and Experimental Immunology. 123:1-8
SUMMARYTo formulate a ‘logic’ for how a single immunoglobulin variable region gene generates antibodies with different antigen specificity and polyreactivity, we analysed chimeric antibodies produced in transgenic mice carrying the germ-line huma
Publikováno v:
Immunology. 98:123-136
The presence of clonally-related B-lymphocyte aggregates within synovial lining tisue of rheumatoid arthritis (RA) patients suggests a germinal centre-like reaction, which may hold implications for disease pathogenesis and the causes of chronic infla
Autor:
Alexander Annenkov, C Herman, K Triantaphyllopoulos, David Baker, Rizgar A. Mageed, David Gould, J L Croxford, Yuti Chernajovsky, Osvaldo L. Podhajcer, Hanna Dreja, S P Moyes
Publikováno v:
Drugs & Aging. 12:29-41
Current understanding of the pathogenesis of rheumatoid arthritis has provided evidence that therapeutic benefit can be achieved by using antagonists targeted to the inflammatory cytokines involved, mainly tumour necrosis factor-alpha and interleukin
Publikováno v:
Annals of the New York Academy of Sciences. 815:296-311
Recent advances in molecular biological and human cell hybridization technology have significantly advanced the knowledge of mechanisms that underlie human rheumatoid factor (RF) production. These advances have provided insight into the etiopathogene
Publikováno v:
International journal of pharmaceutics. 407(1-2)
Microparticle uptake in the small intestine is relevant to both the delivery of pharmaceutics and exposure to environmental pollutants. The Caco-2 enterocyte model is a useful tool to study the parameters that affect epithelial microparticle permeabi
Publikováno v:
International journal of pharmaceutics. 387(1-2)
Small intestinal microparticle uptake via a paracellular route is relevant to oral drug delivery and environmental pollution. In vitro investigation uses latex microparticle passage across a confluent Caco-2 cell epithelium. This paper examines the i