Výsledky vyhledávání - "S. A. McG Thom"

P139 AUTOMATIC CLASSIFICATION OF ARTERIAL AND VENULAR TREES IN COLOUR FUNDUS IMAGES

Autor: Kim H. Parker, Alun D. Hughes, N. Witt, S. A. McG. Thom, M. Elena Martinez-Perez

Publikováno v: Artery Research, Vol 24 (2018)

Background: Quantitative imaging of retinal arterioles and venules offers unique insights into cardiovascular and microvascular diseases but is laborious. We developed and tested a method to automatically identify Arterial/Venular (A/V) vessels in di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18181c35416ada214e96b10e8962f8f9
https://doi.org/10.1016/j.artres.2018.10.192

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The effect of dynamic vessel motion on haemodynamic parameters in the right coronary artery: a combined MR and CFD study

Autor: Guang-Zhong Yang, Ryo Torii, David N. Firmin, Jennifer Keegan, X.Y. Xu, S. A. McG. Thom, Alun D. Hughes, Andrew W. Dowsey, Nigel B. Wood

Publikováno v: The British Journal of Radiology. 82:S24-S32

Human right coronary artery (RCA) haemodynamics is investigated using computational fluid dynamics (CFD) based on subject-specific information from magnetic resonance (MR) acquisitions. The dynamically varying vascular geometry is reconstructed from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56cb27a5a0806e7d217ef51088549546
https://doi.org/10.1259/bjr/62450556

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Analysis of complex flow and the relationship between blood pressure, wall shear stress, and intima-media thickness in the human carotid artery

Autor: Alun D. Hughes, AD Augst, S. A. McG. Thom, Xiao Yun Xu, B Ariff

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 293:H1031-H1037

Background: Previous clinical studies have observed relationships between increased intima-media thickness (IMT) in the carotid artery, elevated blood pressure, and low wall shear stress (WSS) calculated from the Poiseuille equation. This study used

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73d5a8d704bb123523c9c87837122a7d
https://doi.org/10.1152/ajpheart.00989.2006

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Wave-energy patterns in carotid, brachial, and radial arteries: a noninvasive approach using wave-intensity analysis

Autor: Alun D. Hughes, SL Cunningham, Ashraf W. Khir, Andrew Zambanini, S. A. McG. Thom, Kim H. Parker

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 289:H270-H276

The study of wave propagation at different points in the arterial circulation may provide useful information regarding ventriculoarterial interactions. We describe a number of hemodynamic parameters in the carotid, brachial, and radial arteries of no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0e5a2f3bb2049d86cf7c243e6470d8
https://doi.org/10.1152/ajpheart.00636.2003

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Effect of tumour necrosis factor-α and interleukin 1β on endothelium-dependent relaxation in rat mesenteric resistance arteries in vitro

Autor: S Fexby, Alun D. Hughes, S. A. McG. Thom, Ruwan Wimalasundera, Lesley Regan

Publikováno v: British Journal of Pharmacology. 138:1285-1294

Pre-eclampsia is associated with elevated proinflammatory cytokine levels and endothelial dysfunction. This study examined the effect of two cytokines, tumour necrosis factor-α (TNF) and interleukin-1β (IL-1) on endothelium-dependent relaxation in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf0b218c3ef8faaa331fd5b25a42e9a8
https://doi.org/10.1038/sj.bjp.0705168

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Accuracy and Reproducibility of CFD Predicted Wall Shear Stress Using 3D Ultrasound Images

Autor: S. A. McG. Thom, AD Augst, Fadi Glor, Xiao Yun Xu, Dean C. Barratt, Alun D. Hughes

Publikováno v: Journal of Biomechanical Engineering. 125:218-222

Computational fluid dynamics (CFD) flow simulation techniques have the potential to enhance our understanding of how haemodynamic factors are involved in atherosclerosis. Recently, 3D ultrasound has emerged as an alternative to other 3D imaging techn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f67406deec533dca18d78b648693896
https://doi.org/10.1115/1.1553973

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Racial differences in cardiac structure and function in essential hypertension

Autor: Neil R Poulter, J Mayet, Rodney A. Foale, S. A. McG Thom, M Shahi, PS Sever

Publikováno v: BMJ. 308:1011-1014

Objective: To assess racial differences in cardiac structure and function in patients presenting with previously untreated hypertension. Design - Untreated black patients with hypertension were compared with untreated white patients matched for age a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cee9bdd12cc939d90a15ca36d828de2a
https://doi.org/10.1136/bmj.308.6935.1011

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Pre-eclampsia, antiretroviral therapy, and immune reconstitution

Autor: Neil R Poulter, S. A. McG. Thom, Ruwan Wimalasundera, Nick Larbalestier, A de Ruiter, Alun D. Hughes, Graham P. Taylor, JH Smith, Lesley Regan

Publikováno v: The Lancet. 360:1152-1154

Antiretrovirals are standard treatment for HIV-1-positive women during pregnancy in the UK, but little is known about maternal or fetal safety. In our cohort study of 214 pregnant women with HIV-1 infection, those who received no antiretroviral thera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62849b4f5d2d6be4b6b67e71c5b0406f
https://doi.org/10.1016/s0140-6736(02)11195-0

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Indian Asians have poorer cardiovascular autonomic function than Europeans: this is due to greater hyperglycaemia and may contribute to their greater risk of heart disease

Autor: Ronney B. Panerai, S. A. McG. Thom, Darrel P. Francis, John F. Potter, R Bathula, Angela C. Shore, Jaspal S. Kooner, Alun D. Hughes, Nish Chaturvedi

Publikováno v: Diabetologia. 53(10)

A high prevalence of diabetes contributes to excess CHD in Indian Asians, but the underlying mechanisms are unclear. Heart rate, heart rate variability (HRV) and baroreflex sensitivity (BRS) are measures of cardiac autonomic function that are disturb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe029048f402eaae5cbbee26b453e65
https://pubmed.ncbi.nlm.nih.gov/20549180

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Effects of blood pressure lowering and intensive glucose control on the incidence and progression of retinopathy in patients with type 2 diabetes mellitus: a randomised controlled trial

Autor: Joline W.J. Beulens, John Kennedy Cruickshank, Alun D. Hughes, Diederik E. Grobbee, Ronald P. Stolk, J. Lu, Alice Stanton, Johannes R. Vingerling, S. A. McG. Thom, Anushka Patel

Publikováno v: Diabetologia, 52(10), 2027-2036. Springer Verlag
Beulens, J W J, Patel, A, Vingerling, J R, Cruickshank, J K, Hughes, A D, Stanton, A, Lu, J, McG Thom, S A, Grobbee, D E & Stolk, R P 2009, ' Effects of blood pressure lowering and intensive glucose control on the incidence and progression of retinopathy in patients with type 2 diabetes mellitus : A randomised controlled trial ', Diabetologia, vol. 52, no. 10, pp. 2027-2036 . https://doi.org/10.1007/s00125-009-1457-x
Diabetologia, 52(10), 2027-2036. SPRINGER
Diabetologia, 52(10), 2027-2036. Springer-Verlag

The aim of the present study was to investigate the effect of blood pressure lowering and intensive glucose control on the incidence and progression of retinopathy in type 2 diabetic patients.The Action in Diabetes and Vascular Disease: Preterax and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87b98f02ccbf3718563e35b219184856
https://pubmed.ncbi.nlm.nih.gov/19633827

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