Cross Strain Protection against Cytomegalovirus Reduces DISC Vaccine Efficacy against CMV in the Guinea Pig Model

Autor: K. Yeon Choi, Nadia S. El-Hamdi, Alistair McGregor

Publikováno v: Viruses, Vol 14, Iss 4, p 760 (2022)

Congenital cytomegalovirus (CMV) is a leading cause of disease in newborns and a vaccine is a high priority. The guinea pig is the only small animal model for congenital CMV but requires guinea pig cytomegalovirus (GPCMV). Previously, a disabled infe

Externí odkaz: https://doaj.org/article/85dcdb7ef6f54922bbc3ddd9272666d7

Guinea pig cytomegalovirus trimer complex gH/gL/gO uses PDGFRA as universal receptor for cell fusion and entry

Autor: K. Yeon Choi, Alistair McGregor, Nadia S. El-Hamdi

Publikováno v: Virology

Species-specific guinea pig cytomegalovirus (GPCMV) causes congenital CMV and the virus encodes homolog glycoprotein complexes to human CMV, including gH-based trimer (gH/gL/gO) and pentamer-complex (PC). Platelet-derived growth factor receptor alpha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6703a7d9e97774756c98b7b1d4328f4e
https://doi.org/10.1016/j.virol.2020.05.012

Variations in chemotypes patterns of Tunisian Rosmarinus officinalis essential oils and applications for controlling the date moth Ectomyelois ceratoniae (Pyralidae)

Autor: H Jroud, E Bousshih, J Mediouni Ben Jemâa, C Masseoud, S Haouel Hamdi, M Ben Abada

Publikováno v: South African Journal of Botany. 128:18-27

The study explores variations of Rosmarinus officinalis essential oils chemotypes collected from eight sites from north Tunisia and their fumigant toxicity against fifth instar larvae of the date moth Ectomyelois ceratoniae. GC and GC–MS analyses r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f6f0988f9eb7fc80677fc9b73093d1c5
https://doi.org/10.1016/j.sajb.2019.10.010

Guinea Pig Cytomegalovirus Protective T Cell Antigen GP83 Is a Functional pp65 Homolog for Innate Immune Evasion and Pentamer-Dependent Virus Tropism

Autor: Julia Hornig, K. Yeon Choi, Nadia S. El-Hamdi, Alistair McGregor

Publikováno v: J Virol

The guinea pig is the only small animal model for congenital cytomegalovirus (CMV) but requires species-specific guinea pig cytomegalovirus (GPCMV). Tegument protein GP83 is the presumed homolog of HCMV pp65, but gene duplication in the UL82-UL84 hom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f89ae5924d7a87fee48dbdfe49c917
https://doi.org/10.1128/jvi.00324-21

Machine Learning for Better Prognostic Stratification and Driver Gene Identification Using Somatic Copy Number Variations in Anaplastic Oligodendroglioma

Autor: Luc Bauchet, Denys Fontaine, D. Larrieu‐Ciron, M. Andraud, H. Aubriot‐Lorton, Fabien Forest, G. Runavot, Shai Rosenberg, I. Carpiuc, François Labrousse, Christine Desenclos, Annie Laquerrière, Georges Noël, Olivier Chinot, Catherine Godfraind, Patrick Beauchesne, Jean-Yves Delattre, Caroline Dehais, T. Cruel, Danchristian Chiforeanu, F. Dhermain, Dominique Cazals-Hatem, Claude Gaultier, W. Lahiani, Marie-Laure Tanguy, C. Dehais, S. Elouadhani‐Hamdi, Pomone Richard, François Ghiringhelli, Olivier Langlois, Ca. Maurage, Dominique Figarella-Branger, Ahmed Idbaih, Carole Ramirez, Philippe Menei, François Ducray, Benoit Lhermitte, Nabila Elarouci, M. Campone, F. Vandenbos‐Burel, Mj. Motso‐Fotso, C. Blechet, Nicolas Desse, Sandrine Eimer, Valérie Rigau, Agusti Alentorn, Anne Jouvet, Damien Ricard, Mc. Tortel, T. Khallil, Clovis Adam, Hugues Loiseau, L. Bekaert, Henri Sevestre, Chiara Villa, M. Fesneau, Isabelle Quintin-Roue, Antoine Petit, Philippe Colin, Elodie Vauleon, S. Lopez, S. Gaillard, Guillaume Gauchotte, Antoine F. Carpentier, Phong Dam-Hieu, Md. Diebold, Yannick Marie, Thierry Faillot, Serge Milin, Aurélien de Reyniès, Emmanuelle Lechapt-Zalcman, Fabrice Parker, E. Cohen‐Moyal, Delphine Loussouarn, Emmanuelle Uro-Coste, Em. Gueye, Audrey Rousseau, F. Ducray, M‐I Mihai, Aurelie Kamoun, Karima Mokhtari

Publikováno v: Oncologist
Oncologist, AlphaMed Press, 2018, ⟨10.1634/theoncologist.2017-0495⟩
Oncologist, 2018, ⟨10.1634/theoncologist.2017-0495⟩

Background 1p/19q-codeleted anaplastic gliomas have variable clinical behavior. We have recently shown that the common 9p21.3 allelic loss is an independent prognostic factor in this tumor type. The aim of this study is to identify less frequent geno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d39032dc94a5a753c3d34c325b4fd8
https://doi.org/10.1634/theoncologist.2017-0495