Zobrazeno 1 - 10
of 230
pro vyhledávání: '"S. A. Adelstein"'
Autor:
Sarah C. Sasson, Alastair Corbett, Andrew J. McLachlan, R. Chen, S. A. Adelstein, Sean Riminton, Sandhya Limaye
Publikováno v:
Journal of Medical Case Reports, Vol 13, Iss 1, Pp 1-7 (2019)
Abstract Background Myotonic dystrophy type 1 is an autosomal dominant disorder characterized by muscle weakness, myotonia, cataracts, and cardiac conduction defects; it is associated with expansions of cytosine-thymine-guanine repeats in the myotoni
Externí odkaz:
https://doaj.org/article/d65793d5320c4a40b13ad035f65f739a
Publikováno v:
Molecular Imaging, Vol 10 (2011)
Molecular imaging has moved to the forefront of drug development and biomedical research. The identification of appropriate imaging targets has become the touchstone for the accurate diagnosis and prognosis of human cancer. Particularly, cell surface
Externí odkaz:
https://doaj.org/article/843287bb7c5741a68a323fa2cc1fdf83
Publikováno v:
PLoS ONE, Vol 3, Iss 11, p e3661 (2008)
BACKGROUND: With the arrival of the postgenomic era, there is increasing interest in the discovery of biomarkers for the accurate diagnosis, prognosis, and early detection of cancer. Blood-borne cancer markers are favored by clinicians, because blood
Externí odkaz:
https://doaj.org/article/741930e5122f4a7aab35e6de7bfb1afa
Autor:
S. James Adelstein, Kenneth R. Kase
Publikováno v:
Journal of Radiological Protection. 38:873-875
Publikováno v:
Drug Discovery Today. 17:S16-S23
Data mining of available biomedical data and information has greatly boosted target discovery in the 'omics' era. Target discovery is the key step in the biomarker and drug discovery pipeline to diagnose and fight human diseases. In biomedical scienc
Publikováno v:
Chemical Biology & Drug Design. 78:923-931
Human placental alkaline phosphatase has been identified as a hydrolase that is significantly overexpressed on the surface of various solid tumor cells, and is therefore a suitable prodrug design target for non-invasive cancer imaging and therapy. St
Publikováno v:
Analytical Biochemistry. 417:242-246
The widely used agarose gel electrophoresis method for assessing radiation-induced single-strand-break (SSB) yield in plasmid DNA involves measurement of the fraction of relaxed-circular (C) form that migrates independently from the intact supercoile
Publikováno v:
Journal of Nuclear Medicine. 52:1240-1251
The value of pediatric nuclear medicine is well established. Pediatric patients are referred to nuclear medicine from nearly all pediatric specialties including urology, oncology, cardiology, gastroenterology, and orthopedics. Radiation exposure is a
Autor:
David J. Brenner, Mark S. Pearce, Eric J. Hall, Louis K. Wagner, Donald P. Frush, James H. Thrall, Cynthia H. McCollough, Fred A. Mettler, Hedvig Hricak, S. James Adelstein, Roger W. Howell, Orhan H. Suleiman
Publikováno v:
Radiology. 258:889-905
This special report aims to inform the medical community about the many challenges involved in managing radiation exposure in a way that maximizes the benefit-risk ratio. The report discusses the state of current knowledge and key questions in regard
Publikováno v:
Expert Review of Molecular Diagnostics. 10:65-74
Prostate cancer is the most common cancer among men worldwide and is the second leading cause of death among those over 50 years of age in the USA. However, many men who develop a prostate tumor never exhibit symptoms in the early stage of the diseas