Výsledky vyhledávání - "S. A. Plesneva"

[The effect of hypoxia on cholinesterase activity in rat sensorimotor cortex]

Autor: E G, Kochkina, S A, Plesneva, I A, Zhuravin, A J, Turner, N N, Nalivaeva

Publikováno v: Zhurnal evoliutsionnoi biokhimii i fiziologii. 51(2)

This study reports the dynamics of changes in postnatal ontogenesis of the activity of soluble and membrane-bound forms of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) in sensorimotor cortex of rats as well as the pattern of their cha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ca04ba3e7f8bcde8695316532e92cdcb
https://pubmed.ncbi.nlm.nih.gov/26027382

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[Attenuation of inhibitory influence of hormones on adenylyl cyclase systems in the myocardium and brain of rats with obesity and type 2 diabetes mellitus and effect of intranasal insulin on it]

Autor: L A, Kuznetsova, S A, Plesneva, T S, Sharova, M N, Pertseva, A O, Shpakov

Publikováno v: Zhurnal evoliutsionnoi biokhimii i fiziologii. 50(5)

The functional state of the adenylyl cyclase signaling system (ACSS) and its regulation by hormones, the inhibitors of adenylyl cyclase (AC)--somatostatin (SST) in the brain and myocardium and 5-nonyloxytryptamine (5-NOT) in the brain of rats of diff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::53cf8b230a31de767b2461c142d05228
https://pubmed.ncbi.nlm.nih.gov/25786317

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[Study of hormone responsiveness of the adenylyl cyclase signaling system in erythrocyte membranes of patients with type 2 diabetes mellitus]

Autor: L A, Kuznetsova, S A, Plesneva, T C, Sharova, M N, Pertseva

Publikováno v: Patologicheskaia fiziologiia i eksperimental'naia terapiia. (1)

Peptides of the insulin superfamily (insulin, insulin-like growth factor, relaxin), epidermal.growth factor (ECF) and biogenic amines (isoproterenol, adrenalin, noradrenalin, serotonin) stimulate the adenylyl cyclase signaling system (ACSS). In eryth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fe89d6828092738f707079f855014e86
https://pubmed.ncbi.nlm.nih.gov/23805714

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[Regulation of adenylyl cyclase signaling system by insulin, biogenic amines, and glucagon at their separate and combined action in the muscle membranes of the mollusc Anodonta cygnea]

Autor: L A, Kuznetsova, S A, Plesneva, T S, Sharova, M N, Pertseva, A O, Shpakov

Publikováno v: Zhurnal evoliutsionnoi biokhimii i fiziologii. 49(2)

In smooth muscles of mollusc Anodonta cygnea, hormones produce regulatory effects on the adenylyl cyclase (AC) signaling system via receptors of the serpentine (biogenic amine, isoproterenol, glucagon) and of tyrosine kinase (insulin) types. Intracel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::19cd0683a3551819e0d7efc66adebb4e
https://pubmed.ncbi.nlm.nih.gov/23789396

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[Changes in the activity of amyloid-degrading metallopeptidases leads to disruption of memory in rats]

Autor: N M, Dubrovskaia, N N, Nalivaeva, S A, Plesneva, A A, Feponova, A J, Turner, I A, Zhuravin

Publikováno v: Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. 59(5)

In old male Wistar rats (older than 12 months), or adult males (3-4 months) subjected to prenatal hypoxia (7% 02, 3 h, E14), a disruption of short-term memory was observed. The prenatal hypoxia also led to a decrease in the brain cortex expression of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e58800a561dcfe39bb4d86314f4a1827
https://pubmed.ncbi.nlm.nih.gov/19947540

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[Adenylyl cyclase signaling mechanisms of the insulin superfamily peptide action and their impairment in myometrium of pregnant women with type 2 diabetes]

Autor: S a, Plesneva, L A, Kuznetsova, A O, Shpakov, T S, Sharova, M N, Pertseva

Publikováno v: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 94(10)

For the first time we found in myometrium of the women and pregnant women that adenylyl cyclase (AC) stimulating effects of relaxin, insulin and insulin growth factor 1 are realized via six-component AC signaling mechanisms involving the following si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d3f21d985dcda657b5c8b3b4ef13cbb2
https://pubmed.ncbi.nlm.nih.gov/19065826

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[Structural and functional characteristics of the adenylyl cyclase signaling system regulated by biogenic amines and peptide hormones in the muscle of a worm Lumbricus terrestris]

Autor: A O, Shpakov, E A, Shpakova, L A, Kuznetsova, S A, Plesneva, M N, Pertseva

Publikováno v: Zhurnal evoliutsionnoi biokhimii i fiziologii. 44(5)

It has been shown for the first time that biogenic amines (catecholamines and tryptophane derivatives) stimulate dose-dependently activity of adenylyl cyclase (AC) and GTP-binding of G-proteins in muscle of the cutaneous-muscle bag of the earthworm L

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::01f88b891471140376476d5e312b890b
https://pubmed.ncbi.nlm.nih.gov/18959208

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[Structural and functional organization of the adenylyl cyclase signaling mechanism of insulin-like growth factor 1 revealed in the muscle tissue in vertabrates and invertebrates]

Autor: S A, Plesneva, L A, Kuznetsova, A O, Shpakov, T S, Sharova, M N, Pertseva

Publikováno v: Zhurnal evoliutsionnoi biokhimii i fiziologii. 44(5)

Based on the earlier discovered by the authors adenylyl cyclase signaling mechanisms (ACSM) of action of insulin and relaxin, the study was performed of the presence a similar action mechanism of another representative of the insulin superfamily--the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::190a4f0ddfa41eb02ec46acff52e628d
https://pubmed.ncbi.nlm.nih.gov/18959207

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[Streptozocin model of diabetes mellitus in the mollusc Anodonta cygnea: functional state of the adenylyl cyclase mechanisms of action of peptides of the insulin superfamily and their effect on carbohydrate metabolism enzymes]

Autor: L A, Kuznetsova, S A, Plesneva, O V, Chistiakova, A O, Shpakov, V M, Bondareva, M N, Pertseva

Publikováno v: Zhurnal evoliutsionnoi biokhimii i fiziologii. 43(6)

In terms of development of evolutionary biomedicine using invertebrate animals as models for study of molecular grounds of various human diseases, for the first time the streptozocin (ST) model of insulin-dependent diabetes in the mollusc Anodonta cy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eecf2a4fc2a4bbf10b2651acc81f863b
https://pubmed.ncbi.nlm.nih.gov/18265556

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[The disturbance of the transduction of adenylyl cyclase inhibiting hormonal signal in myocardium and brain of rats with experimental type II diabetes]

Autor: A O, Shpakov, L A, Kuznetsova, S A, Plesneva, M N, Pertseva

Publikováno v: Tsitologiia. 49(6)

At present, the data obtained by us and other authors give evidence that disturbances in hormonal signaling systems are the main causes of development of pathological changes and complications under the diabetes. However, the molecular mechanisms of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2c6b37108ee226c8abaca69cff1b9af1
https://pubmed.ncbi.nlm.nih.gov/17802741

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