Zobrazeno 1 - 10
of 35
pro vyhledávání: '"S. -Ja. Tseng"'
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-12 (2024)
Abstract Background As of 2020, hepatocellular carcinoma (HCC), a form of liver cancer, stood as the third most prominent contributor to global cancer-related mortality. Combining immune checkpoint inhibitors (ICI) with other therapies has shown prom
Externí odkaz:
https://doaj.org/article/1e8bf9c3487141c995b9d0cdc63fb155
Publikováno v:
Drug Discovery Today. 26:2508-2514
Targeted-therapy failure in treating nonsmall cell lung cancer (NSCLC) frequently occurs because of the emergence of drug resistance and genetic mutations. The same mutations also result in aerobic glycolysis, which further antagonizes outcomes by lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0acdd1de8fa42f01236e603a871b15b4
https://doi.org/10.1016/j.drudis.2021.07.014
https://doi.org/10.1016/j.drudis.2021.07.014
Publikováno v:
Journal of Controlled Release. 324:482-492
Lung cancer is the primary cause of cancer-related death worldwide. 85%–90% of cases are non-small cell lung cancer (NSCLC) which characteristically exhibits altered epidermal growth factor receptor (EGFR) signaling is a major driver pathway. Unfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b6cf8c0b00c27871bb2d4c89f2f42c3
https://doi.org/10.1016/j.jconrel.2020.05.043
https://doi.org/10.1016/j.jconrel.2020.05.043
Publikováno v:
Nano Today. 47:101688
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f37b3e0d2432fb50201cf32afba17212
https://doi.org/10.1016/j.nantod.2022.101688
https://doi.org/10.1016/j.nantod.2022.101688
Publikováno v:
Nano Today. 46:101582
Refereed/Peer-reviewed Approved targeted therapies for non-small cell lung cancer (NSCLC) though initially effective, often eventually fail due to emergence of drug resistance. This evolution is frequently associated with specific driver mutations an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60a28e2883f6ae710343774760c2d435
https://doi.org/10.1016/j.nantod.2022.101582
https://doi.org/10.1016/j.nantod.2022.101582
Deregulated proliferation of tumors is generally associated with altered energy metabolism. A high rate of anaerobic glycolysis in solid tumors contributes to an acidification of pH to ∼6.7-7.2 in the tumor microenvironment and lactate accumula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f15cfc7aa19dfcf040afe61510f17635
https://hdl.handle.net/11541.2/140111
https://hdl.handle.net/11541.2/140111
Publikováno v:
Advanced Therapeutics. 4:2100048
Liver cancer is one of the most common cancers worldwide, 75% of which are hepatocellular carcinoma (HCC). Generally, chronic inflammation and animmunosuppressive tumor micro environment are steadily activated in HCC. Although the US Food and Drug Ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c415cdb864279123f6cf8032bcd298d9
https://doi.org/10.1002/adtp.202100048
https://doi.org/10.1002/adtp.202100048
Publikováno v:
Biomaterials. 34:4387-4393
Chemically modified antisense RNA oligonucleotides (antagomir) offer promise for cancer therapies but suffer from poor therapeutic effect after systemic administration. Chemical modification or loading in degradable hydrogels can offer improvements i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6033ff464500e47c435c0869b2270d1e
https://doi.org/10.1016/j.biomaterials.2013.02.058
https://doi.org/10.1016/j.biomaterials.2013.02.058
Autor:
Hsiang-Hisn Chen, Yeukuang Hwu, Zi-Xian Liao, Cheng-Liang Wang, Chia-Chi Chien, S.-Ja Tseng, Giorgio Margaritondo, Yi-Da Kang
Publikováno v:
Soft Matter. 8:1420-1427
We successfully demonstrate the in situ formation by X-ray irradiation induced polymerization of a three-dimensional (3D) hydrogel based on poly(ethylene glycol) (PEG) diacrylate (PEG DA), with the option of heparin incorporation to enhance cell adhe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd57bdbc76dd5f93c858011af63bbed1
https://doi.org/10.1039/c1sm06682j
https://doi.org/10.1039/c1sm06682j
Publikováno v:
Cellulose. 18:95-104
We investigated the use of heparinized cellulose matrices (H-CM) as affinity substrates for binding of basic fibroblast growth factor (bFGF), a heparin-binding peptide, to facilitate cellular proliferation and substrate-mediated transgene delivery. U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2c745cc922a3ae7c981d9a31c1d0efa
https://doi.org/10.1007/s10570-010-9456-0
https://doi.org/10.1007/s10570-010-9456-0