Zobrazeno 1 - 10
of 143
pro vyhledávání: '"S. Uygun"'
Autor:
Koustav Roy, Xuzhao Zhou, Rintaro Otani, Ping-Chuan Yuan, Shuji Ioka, Kaspar E. Vogt, Tamae Kondo, Nouran H. T. Farag, Haruto Ijiri, Zhaofa Wu, Youhei Chitose, Mao Amezawa, David S. Uygun, Yoan Cherasse, Hiroshi Nagase, Yulong Li, Masashi Yanagisawa, Manabu Abe, Radhika Basheer, Yi-Qun Wang, Tsuyoshi Saitoh, Michael Lazarus
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Optochemistry, an emerging pharmacologic approach in which light is used to selectively activate or deactivate molecules, has the potential to alleviate symptoms, cure diseases, and improve quality of life while preventing uncontrolled drug
Externí odkaz:
https://doaj.org/article/4431e78e019340f7971afef4a23b66d7
Autor:
David S. Uygun, Radhika Basheer
Publikováno v:
Brain Research Bulletin, Vol 188, Iss , Pp 223-232 (2022)
Sleep is vital and the deepest stages of sleep occur within Non-rapid-eye-movement sleep (NREM), defined by high electroencephalographic power in the delta (~0.5–4 Hz) wave frequency range. Delta waves are thought to facilitate a myriad of physical
Externí odkaz:
https://doaj.org/article/72b1815b268743a8b651e425de902ad4
Autor:
David S. Uygun, Chun Yang, Elena R. Tilli, Fumi Katsuki, Erik L. Hodges, James T. McKenna, James M. McNally, Ritchie E. Brown, Radhika Basheer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Uygun et al. show that deletion of GABAA receptors from the thalamic reticular nucleus using CRISPR gene editing in mice boosts the delta waves, indicating a role for GABAA receptors on thalamic reticular nucleus neurons in NREM sleep delta oscillati
Externí odkaz:
https://doaj.org/article/f103563cadb64548a47d87698d2e0166
Autor:
Robin K. Yuan, Matthew R. Lopez, Manuel-Miguel Ramos-Alvarez, Marc E. Normandin, Arthur S. Thomas, David S. Uygun, Vanessa R. Cerda, Amandine E. Grenier, Matthew T. Wood, Celia M. Gagliardi, Herminio Guajardo, Isabel A. Muzzio
Publikováno v:
Cell Reports, Vol 35, Iss 11, Pp 109234- (2021)
Summary: Poor sleep quality is associated with age-related cognitive decline, and whether reversal of these alterations is possible is unknown. In this study, we report how sleep deprivation (SD) affects hippocampal representations, sleep patterns, a
Externí odkaz:
https://doaj.org/article/363db46d507146ac81515b7f0f0e1959
Akademický článek
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Autor:
S. Uygun
Publikováno v:
Earthline Journal of Mathematical Sciences. :229-249
In this study, we define some tridigional matrices depending on two real parameters. By using the determinant of these matrices, the elements of (s,t)-Pell, (s,t)-Pell Lucas and (s,t)-modified Pell sequences with even or odd indices are generated. Th
Autor:
S. Uygun, H. Karataş
Publikováno v:
Academic Journal of Applied Mathematical Sciences. :136-144
In this study, we introduce a new generalization of the Pell numbers which is called bi-periodic Pell sequences. We then proceed to find the Binet formula as well as the generating function for this sequence. The well-known Cassini, Catalan and the D
Akademický článek
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Autor:
David S, Uygun, Chun, Yang, Elena R, Tilli, Fumi, Katsuki, Erik L, Hodges, James T, McKenna, James M, McNally, Ritchie E, Brown, Radhika, Basheer
Publikováno v:
Nature communications. 13(1)
Identification of mechanisms which increase deep sleep could lead to novel treatments which promote the restorative effects of sleep. Here, we show that knockdown of the α3 GABA
Autor:
E. Schuler, S. Uygun, L. Mittempergher, D. Pronin, S. Mee, S. Bao, T. Cavness, A. Witteveen, A. Glas
Publikováno v:
Annals of Oncology. 33:S232