Zobrazeno 1 - 10
of 961
pro vyhledávání: '"S. Bhagwat"'
Autor:
Philip Barbulescu, Chetan K. Chana, Matthew K. Wong, Ines Ben Makhlouf, Jeffrey P. Bruce, Yuqing Feng, Alexander F. A. Keszei, Cassandra Wong, Rukshana Mohamad-Ramshan, Laura C. McGary, Mohammad A. Kashem, Derek F. Ceccarelli, Stephen Orlicky, Yifei Fang, Huihui Kuang, Mohammad Mazhab-Jafari, Rossanna C. Pezo, Ashok S. Bhagwat, Trevor J. Pugh, Anne-Claude Gingras, Frank Sicheri, Alberto Martin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract A diverse antibody repertoire is essential for humoral immunity. Antibody diversification requires the introduction of deoxyuridine (dU) mutations within immunoglobulin genes to initiate somatic hypermutation (SHM) and class switch recombina
Externí odkaz:
https://doaj.org/article/67ed2463e18d49fc9638e7762e1de9a6
Autor:
Yasha Butt, Ramin Sakhtemani, Rukshana Mohamad-Ramshan, Michael S. Lawrence, Ashok S. Bhagwat
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The APOBEC3 enzymes convert cytosines in single-stranded DNA to uracils to protect against viruses and retrotransposons but can contribute to mutations that diversify tumors. To understand the mechanism of mutagenesis, we map the uracils res
Externí odkaz:
https://doaj.org/article/820624b331134de1a53888915fff2f2b
Autor:
Vinh G. Tran, Somesh Mishra, Sarang S. Bhagwat, Saman Shafaei, Yihui Shen, Jayne L. Allen, Benjamin A. Crosly, Shih-I Tan, Zia Fatma, Joshua D. Rabinowitz, Jeremy S. Guest, Vijay Singh, Huimin Zhao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Microbial production of succinic acid (SA) at an industrially relevant scale has been hindered by high downstream processing costs arising from neutral pH fermentation for over three decades. Here, we metabolically engineer the acid-tolerant
Externí odkaz:
https://doaj.org/article/d06ec3354ea64bd7a97eafb4a9286185
Autor:
Andrea M. Hujer, Steven H. Marshall, Andrew R. Mack, Kristine M. Hujer, Yamuna Devi Bakthavatchalam, Kushal Umarkar, Snehal R. Palwe, Swapna Takalkar, Prashant R. Joshi, Rahul Shrivastava, Hariharan Periasamy, Sachin S. Bhagwat, Mahesh V. Patel, Balaji Veeraraghavan, Robert A. Bonomo
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTMulti-drug resistant (MDR) Pseudomonas aeruginosa harbor a complex array of β-lactamases and non-enzymatic resistance mechanisms. In this study, the activity of a β-lactam/β-lactam-enhancer, cefepime/zidebactam, and novel β-lactam/β-lact
Externí odkaz:
https://doaj.org/article/89cbc21d5db4415483462f4e8fa03ecc
Autor:
Ashish D. Tiple, Shatanik S. Bhagwat
Publikováno v:
Journal of Insect Biodiversity and Systematics, Vol 9, Iss 1, Pp 103-114 (2023)
The present study was carried out to reveal the checklist of butterfly species in the Tadoba National Park, Chandrapur area of 623 sq. km. Study was carried out from 2011 to 2021. A total of 134 species were recorded, with an addition of 27 new recor
Externí odkaz:
https://doaj.org/article/71bb22819e5f42f09827a97eddbbef95
Autor:
Vinh G. Tran, Somesh Mishra, Sarang S. Bhagwat, Saman Shafaei, Yihui Shen, Jayne L. Allen, Benjamin A. Crosly, Shih-I Tan, Zia Fatma, Joshua D. Rabinowitz, Jeremy S. Guest, Vijay Singh, Huimin Zhao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/7dc3c3169b0d477d870926330071c0a7
Autor:
Geeta S. Bhagwat, Rajani B. Athawale, Rajeev P. Gude, Shadab Md, Nabil A. Alhakamy, Usama A. Fahmy, Prashant Kesharwani
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/dffc91008a7a4b85aa19bf9543a2a1b0
Autor:
Adam Langenbucher, Danae Bowen, Ramin Sakhtemani, Elodie Bournique, Jillian F. Wise, Lee Zou, Ashok S. Bhagwat, Rémi Buisson, Michael S. Lawrence
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
The APOBEC mutation signature contributes to a significant percentage of human cancers. Here the authors via biochemical and computational analyses shed light on how DNA primary sequence and secondary structure jointly influence A3A substrate optimal
Externí odkaz:
https://doaj.org/article/0df7d51a696e4dfaa11c6266dbb37d50
Autor:
James D. Byrne, Cameron C. Young, Jacqueline N. Chu, Jennifer Pursley, Mu Xian Chen, Adam J. Wentworth, Annie Feng, Ameya R. Kirtane, Kyla A. Remillard, Cindy I. Hancox, Mandar S. Bhagwat, Nicole Machado, Tiffany Hua, Siddartha M. Tamang, Joy E. Collins, Keiko Ishida, Alison Hayward, Sarah L. Becker, Samantha K. Edgington, Jonathan D. Schoenfeld, William R. Jeck, Chin Hur, Giovanni Traverso
Publikováno v:
Advanced Science, Vol 8, Iss 12, Pp n/a-n/a (2021)
Abstract Cancer patients undergoing therapeutic radiation routinely develop injury of the adjacent gastrointestinal (GI) tract mucosa due to treatment. To reduce radiation dose to critical GI structures including the rectum and oral mucosa, 3D‐prin
Externí odkaz:
https://doaj.org/article/c0323e01371e419f83b88c37c467070f
Autor:
Qiang Yan, Tyler B. Jacobson, Zhou Ye, Yoel R. Cortés-Pena, Sarang S. Bhagwat, Susan Hubbard, William T. Cordell, Rebecca E. Oleniczak, Francesca V. Gambacorta, Julio Rivera Vazquez, Eric V. Shusta, Daniel Amador-Noguez, Jeremy S. Guest, Brian F. Pfleger
Publikováno v:
Metabolic Engineering. 76:18-28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1249eab314b1e62602928087e28d938
https://doi.org/10.1016/j.ymben.2023.01.003
https://doi.org/10.1016/j.ymben.2023.01.003