Výsledky vyhledávání - "S. C. R. WILLIAMS"

Akademický článek

Effects of route of administration on oxytocin-induced changes in regional cerebral blood flow in humans

Autor: D. A. Martins, N. Mazibuko, F. Zelaya, S. Vasilakopoulou, J. Loveridge, A. Oates, S. Maltezos, M. Mehta, S. Wastling, M. Howard, G. McAlonan, D. Murphy, S. C. R. Williams, A. Fotopoulou, U. Schuschnig, Y. Paloyelis

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)

Intranasal oxytocin can affect brain function either by direct entry to the brain or by increasing oxytocin levels in blood plasma. Here, the authors show that increases in plasmatic oxytocin account for some but not all of the changes observed follo

Externí odkaz: https://doaj.org/article/4ed365338ccd41229f9bb811dcce6fae

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Akademický článek

Faulty Suppression of Irrelevant Material in Patients with Thought Disorder Linked to Attenuated Frontotemporal Activation

Autor: S. M. Arcuri, M. R. Broome, V. Giampietro, E. Amaro, T. T. J. Kircher, S. C. R. Williams, C. M. Andrew, M. Brammer, R. G. Morris, P. K. McGuire

Publikováno v: Schizophrenia Research and Treatment, Vol 2012 (2012)

Formal thought disorder is a feature schizophrenia that manifests as disorganized, incoherent speech, and is associated with a poor clinical outcome. The neurocognitive basis of this symptom is unclear but it is thought to involve an impairment in se

Externí odkaz: https://doaj.org/article/15e20e2f1a6a4f429704da2c381dc267

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Corticolimbic hyper-response to emotion and glutamatergic function in people with high schizotypy: a multimodal fMRI-MRS study

Autor: G, Modinos, A, McLaughlin, A, Egerton, K, McMullen, V, Kumari, G J, Barker, C, Keysers, S C R, Williams

Publikováno v: Translational Psychiatry

Animal models and human neuroimaging studies suggest that altered levels of glutamatergic metabolites within a corticolimbic circuit have a major role in the pathophysiology of schizophrenia. Rodent models propose that prefrontal glutamate dysfunctio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::28eeac9fcae0f007ce1f5242c7762f7e
https://pubmed.ncbi.nlm.nih.gov/28375210

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Chronic exposure to haloperidol and olanzapine leads to common and divergent shape changes in the rat hippocampus in the absence of grey-matter volume loss

Autor: W R, Crum, F, Danckaers, T, Huysmans, M-C, Cotel, S, Natesan, M M, Modo, J, Sijbers, S C R, Williams, S, Kapur, A C, Vernon

Publikováno v: Psychological Medicine

Background One of the most consistently reported brain abnormalities in schizophrenia (SCZ) is decreased volume and shape deformation of the hippocampus. However, the potential contribution of chronic antipsychotic medication exposure to these phenom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e0187a5c6160ed360a0cb579d321136b
https://pubmed.ncbi.nlm.nih.gov/27516217

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Using genetic, cognitive and multi-modal neuroimaging data to identify ultra-high-risk and first-episode psychosis at the individual level

Autor: W, Pettersson-Yeo, S, Benetti, A F, Marquand, F, Dell'acqua, S C R, Williams, P, Allen, D, Prata, P, McGuire, A, Mechelli

Publikováno v: Psychological Medicine

Background Group-level results suggest that relative to healthy controls (HCs), ultra-high-risk (UHR) and first-episode psychosis (FEP) subjects show alterations in neuroanatomy, neurofunction and cognition that may be mediated genetically. It is unc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1bc2ecf69507e8f474c871b86040ca19
https://pubmed.ncbi.nlm.nih.gov/23507081

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Neural correlates of movement generation in the 'at-risk mental state'

Autor: Matthew R, Broome, P, Matthiasson, P, Fusar-Poli, J B, Woolley, L C, Johns, P, Tabraham, E, Bramon, L, Valmaggia, S C R, Williams, M J, Brammer, X, Chitnis, P K, McGuire

Publikováno v: Acta psychiatrica Scandinavica. 122(4)

People with 'prodromal' symptoms have a very high risk of developing psychosis. We examined the neurocognitive basis of this vulnerability by using functional MRI to study subjects with an at-risk mental state (ARMS) while they performed a random mov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::21ac2d26be0860ad96bc45b78e92eb58
https://pubmed.ncbi.nlm.nih.gov/20064129

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N-acetyl aspartate estimation: a potential method for determining neuronal loss in the transmissible spongiform encephalopathies

Autor: Y-L, Chung, J, Barr, K, Bhakoo, S C R, Williams, J D, Bell, J R, Fraser

Publikováno v: Neuropathology and applied neurobiology. 29(5)

Neurodegenerative pathology is typical of the transmissible spongiform encephalopathies (TSEs), and is thought to underlie clinical disease. Some morphometric studies have shown early focal neurone loss, but the full extent of TSE induced neuronal lo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3287f2706b3781c8b780c220827980ce
https://pubmed.ncbi.nlm.nih.gov/14507336

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Effects of verbal working memory load on corticocortical connectivity modeled by path analysis of functional magnetic resonance imaging data

Autor: G D, Honey, C H Y, Fu, J, Kim, M J, Brammer, T J, Croudace, J, Suckling, E M, Pich, S C R, Williams, E T, Bullmore

Publikováno v: NeuroImage. 17(2)

We investigated the hypothesis that there are load-related changes in the integrated function of frontoparietal working memory networks. Functional magnetic resonance imaging time-series data from 10 healthy volunteers performing a graded n-back verb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6ffe0e9c4c87a45571968fde9276b818
https://pubmed.ncbi.nlm.nih.gov/12377135

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Functional imaging of the mechanisms underlying the bilateral field advantage

Autor: A M, Santhouse, D H, Ffytche, R J, Howard, S C R, Williams, L, Rifkin, R M, Murray

Publikováno v: NeuroImage. 17(2)

Visual stimulus comparisons across the vertical meridian are faster and more accurate than those restricted to a single hemifield (the bilateral field advantage). We set out to investigate the cerebral mechanisms underlying this effect using function

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::482b2240fa28928c08afffac6417f33b
https://pubmed.ncbi.nlm.nih.gov/12377143

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