Zobrazeno 1 - 10
of 863
pro vyhledávání: '"S-Y. Chan"'
Autor:
Oluwatobi Adegboyega, Suhita Gayen nee’ Betal, Pedro Urday, Rachel Huang, Katherine Bodycot, Huda B. Al-Kouatly, Kolawole Solarin, Joanna S. Y. Chan, Sankar Addya, Rupsa C. Boelig, Zubair H. Aghai
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Methadone maintenance treatment for opioid dependent mothers is standard of care. Infants of methadone maintained opioid dependent (MMOD) mothers have better outcomes compared to infants of opioid dependent mothers without treatment. However
Externí odkaz:
https://doaj.org/article/5bc756145518432c9f258c3cdf9038d5
Autor:
Ioannis Mouratidis, Nikol Chantzi, Umair Khan, Maxwell A. Konnaris, Candace S. Y. Chan, Manvita Mareboina, Camille Moeckel, Ilias Georgakopoulos-Soares
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Early detection of human disease is associated with improved clinical outcomes. However, many diseases are often detected at an advanced, symptomatic stage where patients are past efficacious treatment periods and can result in less favorabl
Externí odkaz:
https://doaj.org/article/83e5bd9eb6b2423d8a916d016a86c015
Autor:
Jennifer K. Y. Ko, Charleen S. Y. Cheung, Heidi H. Y. Cheng, Sofie S. F. Yung, Ting Ying Ng, Winnie W. Y. Tin, Ho Yan Yuen, Martin H. C. Lam, Ann S. Y. Chan, Sara W. W. Fung, Vivian C. M. Man, Ava Kwong, Ernest H. Y. Ng
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Breast cancer is the most common cancer in reproductive age women. The aim of this study is to assess the knowledge, attitude and intention on fertility preservation among women diagnosed to have breast cancer. This is a multi-centre cross-s
Externí odkaz:
https://doaj.org/article/6026e0d5f812439786e925b7ba7b320e
Autor:
Ilias Georgakopoulos-Soares, Chengyu Deng, Vikram Agarwal, Candace S. Y. Chan, Jingjing Zhao, Fumitaka Inoue, Nadav Ahituv
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The gene regulatory code and grammar remain largely unknown, precluding our ability to link phenotype to genotype in regulatory sequences. Here, using a massively parallel reporter assay (MPRA) of 209,440 sequences, we examine all possible p
Externí odkaz:
https://doaj.org/article/e639a6096e204e71ac522a5bd70fb3de
Effects of syphilis infection among HIV-1-positive individuals on suppressive antiretroviral therapy
Autor:
Phillip Chan, Tommy H. C. Tang, Ruby T. S. Kwong, Lawrence Chan, Helen S. Y. Chan, K. W. Lam, W. M. Ting, S. K. Yung, Emily C. T. Lam, M. Y. Chu, Wilson Lam, T. C. Wu, Patrick Li, M. P. Lee
Publikováno v:
AIDS Research and Therapy, Vol 19, Iss 1, Pp 1-5 (2022)
Abstract Introduction Incident syphilis leads to changes in plasma HIV-1 RNA and CD4 + T-cell level in people with HIV (PWH) with viraemia. Its effect in PWH on suppressive antiretroviral therapy (ART) is less clear. Methods PWH on suppressive ART (p
Externí odkaz:
https://doaj.org/article/c5a5473476de43109a27aa2ce40f2af6
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-22 (2022)
Abstract The most stable structure of DNA is the canonical right-handed double helix termed B DNA. However, certain environments and sequence motifs favor alternative conformations, termed non-canonical secondary structures. The roles of DNA and RNA
Externí odkaz:
https://doaj.org/article/fdfc5607482b446db89050780a6b6bf4
Autor:
Bernard C. H. Lee, Philip S. Robinson, Tim H. H. Coorens, Helen H. N. Yan, Sigurgeir Olafsson, Henry Lee-Six, Mathijs A. Sanders, Hoi Cheong Siu, James Hewinson, Sarah S. K. Yue, Wai Yin Tsui, Annie S. Y. Chan, Anthony K. W. Chan, Siu Lun Ho, Peter J. Campbell, Inigo Martincorena, Simon J. A. Buczacki, Siu Tsan Yuen, Suet Yi Leung, Michael R. Stratton
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
It is unclear whether somatic mutation rates are elevated in Lynch Syndrome (LS), which is the most common cause of hereditary colorectal cancer. Here, the authors use whole-genome sequencing and organoid cultures to show that normal tissues in LS pa
Externí odkaz:
https://doaj.org/article/9ffe8e161f6f47b6ae292571819e0a78
Autor:
Tommi Vatanen, O. Sakwinska, B. Wilson, S. Combremont, W. S. Cutfield, S. Y. Chan, K. M. Godfrey, NiPPeR Study Group, Justin M. O’Sullivan
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The infant gut microbiome contains a portion of bacteria that originate from the maternal gut. In the infant gut these bacteria encounter a new metabolic environment that differs from the adult gut, consequently requiring adjustments in thei
Externí odkaz:
https://doaj.org/article/d42784d3ffaf4debbe455ca2c59bca2b
Publikováno v:
ACS Omega, Vol 6, Iss 51, Pp 35325-35333 (2021)
Externí odkaz:
https://doaj.org/article/dac387606cbe43b9859b98a3b5c746b5
Autor:
Anita S. Y. Chan, Sai B. B. Tun, Myoe N. Lynn, Candice Ho, Tin A. Tun, Michaël J. A. Girard, Rehena Sultana, Veluchamy A. Barathi, Tin Aung, Makoto Aihara
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 961 (2023)
Current management of glaucomatous optic neuropathy is limited to intraocular pressure control. Neuroglobin (Ngb) is an endogenous neuroprotectant expressed in neurons and astrocytes. We recently showed that exogenous intravitreal Ngb reduced inflamm
Externí odkaz:
https://doaj.org/article/49204e93774040e09acd8a456354b328