Zobrazeno 1 - 10
of 492
pro vyhledávání: '"S-I. Hakomori"'
Autor:
Y. Shida, Y. Miyata, T. Hakariya, Y. Nakamura, T. Matsuo, K. Ohba, T. Taima, A. Ito, T. Suda, S-I. Hakomori, S. Saito, H. Sakai
Publikováno v:
European Urology Open Science, Vol 19, Iss , Pp e1572- (2020)
Externí odkaz:
https://doaj.org/article/40937db8993b440f934cc16d628f3e90
Autor:
T. Hakariya, Arisa Ito, Toshio Suda, Y. Nakamura, K. Ohba, Y. Shida, Hideki Sakai, Shin Saito, T. Taima, S-I. Hakomori, Y. Miyata, T. Matsuo
Publikováno v:
European Urology Open Science, Vol 19, Iss, Pp e1572-(2020)
Autor:
Michael Buerke, J. Margiotta, S.-I. Hakomori, Allan M. Lefer, Toyoaki Murohara, Y. Igarashi, Fuqiang Ruan
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 269:H504-H514
N,N,N-trimethylsphingosine (TMS), a stable synthetic sphingosine derivative, was investigated in a feline model of myocardial ischemia (90 min) and reperfusion (270 min) injury. TMS (60 micrograms/kg), administered intravenously 10 min before reperfu
Autor:
N. Kojima, S.-I. Hakomori
Publikováno v:
Journal of Biological Chemistry. 266:17552-17558
Cell lines expressing varying levels of ganglioside GM3 at the cell surface show different degrees of adhesion and spreading on solid phase coated with such glycosphingolipids (GSLs) as Gg3 (GalNAc beta 1—-4Gal beta 1—-4Glc beta 1—-1Cer), LacCe
Autor:
S.-I. Hakomori
Publikováno v:
Journal of Biological Chemistry. 265:18713-18716
Glycosphingolipids (GSLs), or their modified catabolites, at the cell surface modulate transmembrane signal transduction by influencing protein kinases associated with growth factor receptors and protein kinase C. On the other hand, the same or diffe
Publikováno v:
Glycoconjugate journal. 18(7)
The importance of analogues of lactosyl ceramides as basic structures of many natural glycosphingolipids provided a rationale for developing an efficient synthetic route to these compounds. We report herein a novel approach to synthesize several memb
Autor:
A, Ito, S, Saito, T, Masuko, M, Oh-Eda, T, Matsuura, M, Satoh, F M, Nejad, T, Enomoto, S, Orikasa, S I, Hakomori
Publikováno v:
Glycoconjugate journal. 18(6)
Renal cell carcinoma (RCC) has been characterized by high expression of three types of disialogangliosides: two based on lacto-series type 1 structure (disialosyl Lc(4), GalNAc disialosyl Lc(4)), the other based on globo-series structure (disialosyl
Autor:
S I, Hakomori
Publikováno v:
Glycoconjugate journal. 17(3 -4)
Glycosphingolipids (GSLs) and sphingomyelin in animal cells are clustered and organized as membrane microdomains closely associated with various signal transducer molecules such as cSrc, Src family kinases, small G-proteins (e.g., RhoA, Ras), and foc
Autor:
Makoto Satoh, Seiichi Orikasa, Shigeyoshi Saito, Akihiro Ito, Chikara Ohyama, Haruo Ohtani, Fatemeh Moosavi Nejad, S.-I. Hakomori
Publikováno v:
Scopus-Elsevier
Disialylgalactosylgloboside (DSGG), defined by monoclonal antibody RM2, is a renal cell carcinoma (RCC)-associated antigen which mediates adhesion of RCC TOS-1 cells to certain lung tissue target cells. This adhesion process may initiate preferential
Publikováno v:
Glycoconjugate journal. 14(1)
Employing a new procedure, we established many monoclonal antibodies (mAbs) which inhibit E- or P-selectin-dependent cell adhesion. One of these mAbs is capable of staining selectin in paraffin-embedded histological sections. The procedure is based o