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Akademický článek
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Publikováno v:
The Malaysian journal of pathology. 43(2)
Autophagy is a host defensive mechanism responsible for eliminating harmful cellular components through lysosomal degradation. Autophagy has been known to either promote or suppress various cancers including colorectal cancer (CRC). KRAS mutation ser
Publikováno v:
The Malaysian journal of pathology. 42(1)
Autophagy is a mechanism that degrades large damaged organelles and misfolded proteins to maintain the homeostasis in all cells. It plays double-faceted roles in tumourigenesis and prevention of various cancers. In our side observation of investigati
Publikováno v:
The Malaysian journal of pathology. 40(1)
Epstein-Barr virus (EBV) might be an aetiological agent involved in the pathogenesis of certain Non-Hodgkin's Lymphomas (NHLs). EBV infection has been diagnosed by serologic testing within the tumour biopsies of patients with NHL. However, the associ
Akademický článek
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Autor:
Tjasso Blokzijl, Sibrand Poppema, A.M. van den Berg, Joost Kluiver, M Boot, Megan S. Lim, S-C Peh, WA Kamps, Lydia Visser, Arjan Diepstra, Renata Rust, Geertruida Harms
Publikováno v:
Journal of Clinical Pathology, 58(5), 520-524. BMJ PUBLISHING GROUP
Aim: To gain more insight into the genes involved in the aetiology and pathogenesis of anaplastic large cell lymphoma (ALCL).Methods: Serial analysis of gene expression ( SAGE) was undertaken on the CD4+ALK+ ( anaplastic lymphoma kinase positive) ALC
Publikováno v:
Asia-Oceania Journal of Obstetrics and Gynaecology. 13:55-57
Following a quick vaginal delivery of a preterm infant, the placenta was delivered with some difficulty. A globular mass approximately 10 cm in diameter was seen attached to the maternal surface of the placenta by large veins. Histology revealed it t
Publikováno v:
The Malaysian journal of pathology. 35(1)
Malignant transformation from normal colonic mucosa to carcinomas may be accelerated by genetic loss or inactivation of genes of the DNA mismatch repair system. The aim of the study was to determine the local incidence and pattern of immunohistochemi
Publikováno v:
The Medical journal of Malaysia. 63(4)
Amyloidosis of the skull base is a rare entity. A patient with localized amyloidosis of the sphenoid sinus presented at our institution with cerebrospinal fluid rhinorrhoea. Endoscopic excision of the lesion and multilayered obliteration of the sphen
Publikováno v:
The Medical journal of Malaysia. 61(5)
Gastrointestinal stromal tumour (GIST) is a rare but most common mesenchymal tumour in the gastrointestinal tract. Although GIST research has been carried out extensively worldwide, it has yet to be studied in Malaysia. To establish the immunohistoch