Zobrazeno 1 - 10
of 2 456
pro vyhledávání: '"S protein"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Porcine epidemic diarrhea virus (PEDV) is a serious disease that poses a significant threat to the pig industry. This study focused on analyzing the Spike protein of PEDV, which harbors crucial antigenic determinants, in identifying dominant
Externí odkaz:
https://doaj.org/article/fe3ac842f2e2484c9ab24acae58bc3c4
Autor:
Ekaterina A. Volosnikova, D. N. Shcherbakov, N. V. Volkova, T. I. Esina, A. V. Zaikovskaya, G. G. Shimina, E. D. Danilenko
Publikováno v:
Инфекция и иммунитет, Vol 14, Iss 3, Pp 569-574 (2024)
To increase the effectiveness and immunogenicity of modern vaccines, especially subunit ones, it is required to use adjuvants. Polysaccharides, due to their safety and biocompatibility, are desirable candidates for the creation of vaccine adjuvants.
Externí odkaz:
https://doaj.org/article/1b4afcc6ae144ccab99a3e6fcac97e3d
Autor:
Patricia Pérez, David Astorgano, Guillermo Albericio, Sara Flores, Cristina Sánchez-Corzo, María A. Noriega, Pedro J. Sánchez-Cordón, Nuria Labiod, Rafael Delgado, José M. Casasnovas, Mariano Esteban, Juan García-Arriaza
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Despite the decrease in mortality and morbidity due to SARS-CoV-2 infection, the incidence of infections due to Omicron subvariants of SARS-CoV-2 remains high. The mutations acquired by these subvariants, mainly concentrated in the receptor-binding d
Externí odkaz:
https://doaj.org/article/b69fc8f2add74e3e99b368fc45aaa79c
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Based on the whole virus or spike protein of pigs, δ coronavirus (PDCoV) as an immunogen may have unrelated antigenic epitope interference. Therefore, it is essential for screening and identifying advantageous protective antigen epitopes. In additio
Externí odkaz:
https://doaj.org/article/453cd1dc28ea421a8a3aaa040887c5d6
Autor:
Yuyao Guo, Ling Sui, Deming Kong, Dan Liu, Yueyi Gao, Yanping Jiang, Wen Cui, Jiaxuan Li, Yijing Li, Li Wang
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-13 (2024)
Abstract Background Porcine epidemic diarrhea (PED) is an infectious disease of the digestive tract caused by the porcine epidemic diarrhea virus (PEDV), characterized by vomiting, severe diarrhea, and high mortality rates in piglets. In recent years
Externí odkaz:
https://doaj.org/article/350f6b49a86b4fa3b00e303e55956fa9
Publikováno v:
Медицинская иммунология, Vol 26, Iss 2, Pp 345-354 (2024)
An important area of research concerns monitoring of immune response features in patients with SARS-CoV-2 infection as well as their analysis, as compared with characteristics of vaccine-mediated protection, in order to specify the determinants of ce
Externí odkaz:
https://doaj.org/article/5fdb628e89b14de988e46300d7801bf2
Autor:
Yara Atef, Tomoya Ito, Akitsu Masuda, Yuri Kato, Akiyuki Nishimura, Yasunari Kanda, Jun Kunisawa, Takahiro Kusakabe, Motohiro Nishida
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10379 (2024)
During the COVID-19 pandemic, diabetic and obese patients experienced higher rates of hospital admissions, severe illness, and mortality. However, vaccinations failed to provide those vulnerable populations the same level of protection against COVID-
Externí odkaz:
https://doaj.org/article/55eb3f1f283c4a5fa5f16318c8d47975
Autor:
Haojian Luo, Zhaoping Liang, Junjie Lin, Yiqiao Wang, Yingying Liu, Kun Mei, Mengmeng Zhao, Shujian Huang
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Porcine epidemic diarrhea virus (PEDV) is a single-stranded RNA virus with a capsid membrane that causes acute infectious gastrointestinal disease characterized by vomiting, diarrhea, and dehydration in swine. Piglets are more susceptible to PEDV tha
Externí odkaz:
https://doaj.org/article/af70b5d388fd4503b6de6a679c725293
Autor:
Shohei Minami, Tomohiro Kotaki, Yusuke Sakai, Shinya Okamura, Shiho Torii, Chikako Ono, Daisuke Motooka, Rina Hamajima, Ryotaro Nouda, Jeffery A. Nurdin, Moeko Yamasaki, Yuta Kanai, Hirotaka Ebina, Yusuke Maeda, Toru Okamoto, Taro Tachibana, Yoshiharu Matsuura, Takeshi Kobayashi
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 4 (2024)
ABSTRACTSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) utilizes several host proteases to cleave the spike (S) protein to enter host cells. SARS-CoV-2 S protein is cleaved into S1 and S2 subunits by furin, which is closely involved in t
Externí odkaz:
https://doaj.org/article/52bcfaa75fde4976b2cff269b2a83cf6
Autor:
Anais N. Bauer, John F. Williams, Lok R. Pokhrel, Selena Garcia, Niska Majumdar, Jeffrey B. Eells, Paul P. Cook, Shaw M. Akula
Publikováno v:
Toxics, Vol 12, Iss 7, p 495 (2024)
Smart Nano-enabled Antiviral Therapeutic (SNAT) is a promising nanodrug that previously demonstrated efficacy in preclinical studies to alleviate SARS-CoV-2 pathology in hamsters. SNAT comprises taxoid (Tx)-decorated amino (NH2)-functionalized near-a
Externí odkaz:
https://doaj.org/article/c47b1d18a2a84e449a24de4c0ccf75b1