Zobrazeno 1 - 10
of 1 052
pro vyhledávání: '"S Wasserman"'
Autor:
Jason S. Wasserman, Holly Fowle, Rumesa Hashmi, Diba Atar, Kishan R. Patel, Amir Yarmahmoodi, Alexander W. Macfarlane, Yinfei Tan, Edna Cukierman, Bojana Gligorijevic, Adam Karami, Kelly A. Whelan, Kerry S. Campbell, Xavier Graña
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Prostate cancer (PCa) is the most common cancer diagnosed in men worldwide and was the second leading cause of cancer-related deaths in US males in 2022. Prostate cancer also represents the second highest cancer mortality disparity between n
Externí odkaz:
https://doaj.org/article/398f3efd1a784589babef813afa2a8f6
Autor:
Jason S. Wasserman, Bulat Faezov, Kishan R. Patel, Alison M. Kurimchak, Seren M. Palacio, David J. Glass, Holly Fowle, Brennan C. McEwan, Qifang Xu, Ziran Zhao, Lauren Cressey, Neil Johnson, James S. Duncan, Arminja N. Kettenbach, Roland L. Dunbrack, Xavier Graña
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The Ser/Thr protein phosphatase 2 A (PP2A) regulates the dephosphorylation of many phosphoproteins. Substrate recognition are mediated by B regulatory subunits. Here, we report the identification of a substrate conserved motif [RK]-V-x-x-[VI
Externí odkaz:
https://doaj.org/article/6e9017a5c5d34b82817862a82164f6a6
Autor:
Jason S. Wasserman, Felicity Feiser, Seren Palacio, Kishan Patel, Joy Gonzalez, Holly Fowle, Xavier Graña
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102148- (2023)
Summary: Serine/threonine protein phosphatase 2 (PP2A) forms heterotrimeric holoenzymes, where a scaffold subunit bridges the PP2A catalytic subunit to a B regulatory subunit, e.g., B55α. The PP2A/B55α holoenzyme plays key roles in signaling and ce
Externí odkaz:
https://doaj.org/article/85f939693b01439dabf9e565d7deac41
Autor:
L. Guglielmetti, E. Ardizzoni, M. Atger, E. Baudin, E. Berikova, M. Bonnet, E. Chang, S. Cloez, J. M. Coit, V. Cox, B. C. de Jong, C. Delifer, J. M. Do, D. Dos Santos Tozzi, V. Ducher, G. Ferlazzo, M. Gouillou, A. Khan, U. Khan, N. Lachenal, A. N. LaHood, L. Lecca, M. Mazmanian, H. McIlleron, M. Moschioni, K. O’Brien, O. Okunbor, L. Oyewusi, S. Panda, S. B. Patil, P. P. J. Phillips, L. Pichon, P. Rupasinghe, M. L. Rich, N. Saluhuddin, K. J. Seung, M. Tamirat, L. Trippa, M. Cellamare, G. E. Velásquez, S. Wasserman, P. J. Zimetbaum, F. Varaine, C. D. Mitnick
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-15 (2021)
Abstract Background Treatment of multidrug- and rifampin-resistant tuberculosis (MDR/RR-TB) is expensive, labour-intensive, and associated with substantial adverse events and poor outcomes. While most MDR/RR-TB patients do not receive treatment, many
Externí odkaz:
https://doaj.org/article/85bd589a0cd64486abc5fda915c2f7c5
Autor:
Robert Edelman, Meagan E. Deming, Franklin R. Toapanta, Mark D. Heuser, Lisa Chrisley, Robin S. Barnes, Steven S. Wasserman, William C. Blackwelder, Barry S. Handwerger, Marcela Pasetti, Khan M. Siddiqui, Marcelo B. Sztein
Publikováno v:
Immunity & Ageing, Vol 17, Iss 1, Pp 1-16 (2020)
Abstract Background Reduced response to hepatitis B vaccines is associated with aging, confounding and comorbid conditions, as well as inadvertent subcutaneous (SC) inoculation. We hypothesized that the antibody and T cell-mediated immune responses (
Externí odkaz:
https://doaj.org/article/97d087551e654b738593dafe6a0aa4c6
Autor:
Benjamin M. Laitman, Peter Filip, Sunder Gidumal, Joshpaul Jolly, Randi S. Wasserman, Barbara M. Dilos, Jasmine Dave, Samuel J. Trosman
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 6, Iss 2, Pp 362-364 (2021)
Externí odkaz:
https://doaj.org/article/688bd525f8cd4e6a8367e229a3da0c55
Autor:
Holly Fowle, Ziran Zhao, Qifang Xu, Jason S Wasserman, Xinru Wang, Mary Adeyemi, Felicity Feiser, Alison N Kurimchak, Diba Atar, Brennan C McEwan, Arminja N Kettenbach, Rebecca Page, Wolfgang Peti, Roland L Dunbrack, Xavier Graña
Publikováno v:
eLife, Vol 10 (2021)
Protein phosphorylation is a reversible post-translation modification essential in cell signaling. This study addresses a long-standing question as to how the most abundant serine/threonine protein phosphatase 2 (PP2A) holoenzyme, PP2A/B55α, specifi
Externí odkaz:
https://doaj.org/article/6761c6a9c42749159283c5b22082407f
Autor:
Jessica S. Wasserman, Roee Holtzer
Publikováno v:
Experimental Aging Research. :1-16
Autor:
Raviteja R, Guddeti, Cristina, Sanina, Rajiv, Jauhar, Timothy D, Henry, Payam, Dehghani, Ross, Garberich, Christian W, Schmidt, Keshav R, Nayak, Jay S, Shavadia, Akshay, Bagai, Chadi, Alraies, Aditya, Mehra, Rodrigo, Bagur, Cindy, Grines, Avneet, Singh, Rajan A G, Patel, Wah Wah, Htun, Nima, Ghasemzadeh, Laura, Davidson, Deepak, Acharya, Ameer, Kabour, Abdul Moiz, Hafiz, Shy, Amlani, Hal S, Wasserman, Timothy, Smith, Navin K, Kapur, Santiago, Garcia
Publikováno v:
The American Journal of Cardiology. 187:76-83
ST-segment elevation myocardial infarction (STEMI) complicating COVID-19 is associated with an increased risk of cardiogenic shock and mortality. However, little is known about the frequency of use and clinical impact of mechanical circulatory suppor
Autor:
Michael S Wasserman, Ali Guermazi, Mohamed Jarraya, Lars Engbretsen, Mohamad AbdelKader, Frank W Roemer, Daichi Hayashi, Michel D Crema, Asim Z Mian
Publikováno v:
BMJ Open Sport & Exercise Medicine, Vol 4, Iss 1 (2018)
Background/aim In high-level Olympic athletes, many spinal pathologies arise from overuse, while others are the result of acute injury. Our aim is to analyse the epidemiology of spinal pathologies detected on MRI in athletes participating in the 2016
Externí odkaz:
https://doaj.org/article/5cd535f1fab5496e80645203a58e63a4