Zobrazeno 1 - 9 of 9 pro vyhledávání: '"S W Muchmore"'
2
Crystal structure and mutagenic analysis of the inhibitor-of-apoptosis protein survivin
Autor: S W, Muchmore, J, Chen, C, Jakob, D, Zakula, E D, Matayoshi, W, Wu, H, Zhang, F, Li, S C, Ng, D C, Altieri
Publikováno v: Molecular cell. 6(1)
The coupling of apoptosis (programmed cell death) to the cell division cycle is essential for homeostasis and genomic integrity. Here, we report the crystal structure of survivin, an inhibitor of apoptosis, which has been implicated in both control o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::614a2c6c8d827366de9417db7f219184
https://pubmed.ncbi.nlm.nih.gov/10949038
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3
Structure of secreted aspartic proteinases from Candida. Implications for the design of antifungal agents
Autor: C, Abad-Zapatero, R, Goldman, S W, Muchmore, C, Hutchins, T, Oie, K, Stewart, S M, Cutfield, J F, Cutfield, S I, Foundling, T L, Ray
Publikováno v: Advances in experimental medicine and biology. 436
Pathogens of the genus Candida can cause life threatening infections in immuno-compromised patients. The three-dimensional structures of two closely related secreted aspartic proteinases from C. albicans complexed with a potent (Ki = 0.17 nM) inhibit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6d00f25b6b13ee08019e790a8cc919a1
https://pubmed.ncbi.nlm.nih.gov/9561233
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4
The crystal structure of a lysine 49 phospholipase A2 from the venom of the cottonmouth snake at 2.0-A resolution
Autor: D R, Holland, L L, Clancy, S W, Muchmore, T J, Ryde, H M, Einspahr, B C, Finzel, R L, Heinrikson, K D, Watenpaugh
Publikováno v: The Journal of biological chemistry. 265(29)
The crystal structure of a lysine 49 variant phospholipase A2 (K49 PLA2) has been determined at 2.0-A resolution. This particular phospholipase A2, purified from the venom of the eastern cottonmouth (Agkistrodon piscivorus piscivorus), a North Americ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e139504c3c27c596ab3413c3f6ce1b92
https://pubmed.ncbi.nlm.nih.gov/2120215
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9
Synthesis and antiarrhythmic properties of novel 3-selena-7-azabicyclo[3.3.1]nonanes and derivatives. Single-crystal X-ray diffraction analysis of 7-benzyl-3-selena-7-azabicyclo[3.3.1]nonan-9-one and 7-benzyl-3-selena-7-azabicyclo[3.3.1]nonane hydroperchlorate
Autor: van der Helm D, Gary S. Smith, Kenneth Berlin, Thompson, Benjamin J. Scherlag, K. A. Fidelis, S. W. Muchmore, Elizabeth M. Holt
Publikováno v: Journal of medicinal chemistry. 30(5)
Several members of the heterocyclic family 3-selena-7-azabicyclo[3.3.1]nonane have been synthesized and characterized via IR, 1H, 13C, 15N, and 77Se NMR spectroscopy and, in some cases, by X-ray diffraction analysis. Select members, namely the hydrop
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59e6b1981de4e59a0035a2fc83f7bda0
https://pubmed.ncbi.nlm.nih.gov/3572967
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