Zobrazeno 1 - 10
of 28
pro vyhledávání: '"S W, Kessler"'
Autor:
Joseph D. Mosca, Z. Yu, J. H. Kim, Sumesh Kaushal, Liyanage P. Perera, Eric R. Hall, V. F. La Russa, S. W. Kessler, S. Gartner
Publikováno v:
Journal of Biomedical Science. 4:61-68
In order to develop a convenient small-animal model that can support the differentiation of human bone-marrow-derived CD34+ cells, we transplanted SCID mice with an immortalized human stromal cell line, Lof(11-10). The Lof(11-10) cell line has been c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e7aad0b2b4a5a8c07e3d61115b92751
https://doi.org/10.1159/000456967
https://doi.org/10.1159/000456967
Autor:
S. W. Kessler, J. F. Perdue, Janet M. Szabo, K. Sakano, A. Pashapour, Ronald E. Gress, G. N. Schwartz, M. K. Warren
Publikováno v:
STEM CELLS. 14:337-350
This report presents the results of studies investigating the effect of insulin-like growth factor II (IGF-II) on the proliferation and differentiation of CD34+ bone marrow cells in serum-substituted liquid cultures. Bone marrow cells were enriched f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::029b9393a4b5ca7c36f670815a3ad091
https://doi.org/10.1002/stem.140337
https://doi.org/10.1002/stem.140337
Publikováno v:
Journal of Leukocyte Biology. 57:948-955
This report presents results concerning the potential role of negative regulators in hematopoietic suppression observed in human immunodeficiency virus (HIV)-infected long-term cultures (LTC) of human bone marrow cells. Confluent stromal cell layers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e559c897058fd32de8590b2e4c611bd
https://doi.org/10.1002/jlb.57.6.948
https://doi.org/10.1002/jlb.57.6.948
Autor:
D M, Bodine, T, Moritz, R E, Donahue, B D, Luskey, S W, Kessler, D I, Martin, S H, Orkin, A W, Nienhuis, D A, Williams
Publikováno v:
Blood. 82:1975-1980
Retroviral mediated gene transfer into stem cells has been proposed as therapy for many inherited hematopoietic diseases. Deficiency of the enzyme adenosine deaminase (ADA) results in depletion of T lymphocytes, causing severe combined immunodeficien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d5a1f4074561461b3628f99756a442f
https://doi.org/10.1182/blood.v82.7.1975.1975
https://doi.org/10.1182/blood.v82.7.1975.1975
Autor:
S K Stanley, S W Kessler, J S Justement, S M Schnittman, J J Greenhouse, C C Brown, L Musongela, K Musey, B Kapita, A S Fauci
Publikováno v:
The Journal of Immunology. 149:689-697
Individuals infected with HIV frequently develop cytopenias and suppressed hematopoiesis. The role of direct HIV infection of hematopoietic progenitor cells in this process has not been defined. In this study, purified CD34+ bone marrow progenitor ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c4f29d5cb7f6508b1241eb3b3284515
https://doi.org/10.4049/jimmunol.149.2.689
https://doi.org/10.4049/jimmunol.149.2.689
Publikováno v:
The Journal of Immunology. 148:772-777
Hemopoietic stem cell factor (SCF), which is the ligand for the proto-oncogene c-kit receptor (allelic with W locus) and the product of Sl locus of the mouse, has recently been cloned. The human homologue has also been cloned, and recombinant protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5af8272f0ae62767f2163adef937baa0
https://doi.org/10.4049/jimmunol.148.3.772
https://doi.org/10.4049/jimmunol.148.3.772
Publikováno v:
The Journal of Immunology. 146:1410-1415
It has been established that murine mast cells are derived from a pluripotent bone marrow stem cell. In humans, the corresponding pluripotent cell is included in the CD34+ bone marrow population. To determine whether human mast cells arise from CD34+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da556aa581d53723b29ab2826f638fcc
https://doi.org/10.4049/jimmunol.146.5.1410
https://doi.org/10.4049/jimmunol.146.5.1410
Autor:
V F, La Russa, S W, Kessler, V A, Henson, M, Cutting, T, Polsinelli, R D, Knight, D G, Wright
Publikováno v:
Experimental hematology. 24(13)
We have examined the capacity of highly purified human CD34+ marrow cell isolates from unrelated, HLA-mismatched donors to establish in vitro hematopoiesis on recipient marrow stromal cells in 2-stage hematopoietic long-term marrow cultures (H-LTMC).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::89fb75982ccff1a49fbe599dd314c576
https://pubmed.ncbi.nlm.nih.gov/8950230
https://pubmed.ncbi.nlm.nih.gov/8950230
Autor:
Brian A. Agricola, Martha Kirby, Stephanie L. Sellers, Lingyan Xu, Stefanie Kluepfel-Stahl, Stefan Karlsson, S W Kessler, Ellen Byrne, Cynthia E. Dunbar, Roscoe O. Brady
Successful gene transfer into stem cells would provide a potentially useful therapeutic modality for treatment of inherited and acquired disorders affecting hematopoietic tissues. Coculture of primate bone marrow cells with retroviral producer cells,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54af513debc86eb8a25d75f33783dc04
https://europepmc.org/articles/PMC41946/
https://europepmc.org/articles/PMC41946/
Publikováno v:
Blood. 85(7)
Primary autologous as well as allogeneic and xenogeneic stroma will support human stem cell proliferation and differentiation for several months. In the present study, we investigated the capacity of porcine microvascular endothelial cells (PMVECs) t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2eb06ca13d5c5207e02e301cbdb8baf7
https://pubmed.ncbi.nlm.nih.gov/7535587
https://pubmed.ncbi.nlm.nih.gov/7535587