Zobrazeno 1 - 5
of 5
pro vyhledávání: '"S W, Grimm"'
Autor:
Celia A. Balfour, J. C. Stevens, Karen M. Kedzie, James R. Halpert, G. Y. Escobar, S. W. Grimm, You-Ai He, John W. Regan, D. J. Pepperl
Publikováno v:
Journal of Biological Chemistry. 266:22515-22521
Liver microsomes from phenobarbital-treated rats of four inbred strains expressing distinct allelic variants of cytochrome P450IIB1 were analyzed. The Wistar Munich (WM) strain exhibited 5- to 10-fold lower androstenedione 16 beta-hydroxylase activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15dc8f1f49a59906432d67613a0f9814
https://doi.org/10.1016/s0021-9258(18)54602-0
https://doi.org/10.1016/s0021-9258(18)54602-0
Autor:
S W, Grimm, M C, Dyroff
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 25(5)
Anastrozole (2,2'[5(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]- bis(2-methylproprionitrile)) is a potent third-generation inhibitor of aromatase, currently marketed as a treatment for postmenopausal women with advanced breast cancer. While its poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d74b7a075b8e45817bbe09f209259746
https://pubmed.ncbi.nlm.nih.gov/9152599
https://pubmed.ncbi.nlm.nih.gov/9152599
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 23(5)
The kinetics of mechanism-based inactivation of phenobarbital-inducible rabbit hepatic cytochromes P450 2B4 and 2B5 by N-benzyl-(BBT) and N-alpha-methylbenzyl (alpha MB) 1-aminobenzotriazole were investigated using reconstituted P450 2B4, a stable he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a3594d2c2ec4d6fc28fc9d4a63accd8f
https://pubmed.ncbi.nlm.nih.gov/7587934
https://pubmed.ncbi.nlm.nih.gov/7587934
Publikováno v:
Molecular pharmacology. 46(6)
Cytochrome P450 (P450) 2B5 was recently found to be functionally distinct from three other rabbit P450 2B forms, based on androstenedione hydroxylase activities. In this investigation, we examined the frequency of the P450 2B5-null phenotype and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0099de90de2eb552b0aa6a6c1359141a
https://pubmed.ncbi.nlm.nih.gov/7808429
https://pubmed.ncbi.nlm.nih.gov/7808429
Autor:
K M, Kedzie, C A, Balfour, G Y, Escobar, S W, Grimm, Y A, He, D J, Pepperl, J W, Regan, J C, Stevens, J R, Halpert
Publikováno v:
The Journal of biological chemistry. 266(33)
Liver microsomes from phenobarbital-treated rats of four inbred strains expressing distinct allelic variants of cytochrome P450IIB1 were analyzed. The Wistar Munich (WM) strain exhibited 5- to 10-fold lower androstenedione 16 beta-hydroxylase activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8fd50506077bfd6e607581f69822975a
https://pubmed.ncbi.nlm.nih.gov/1718996
https://pubmed.ncbi.nlm.nih.gov/1718996