Zobrazeno 1 - 10 of 21 pro vyhledávání: '"S W, Fesik"'
1
Tumor vasculature is a key determinant for the efficiency of nanoparticle-mediated siRNA delivery
Autor: J Song, Xiaoyu Lin, William M. Kohlbrenner, S W Fesik, Rongqi Wang, X Zhao, Leiming Li, Y Shen, Denise Wilcox
Publikováno v: Gene Therapy
Delivering small interfering RNA (siRNA) to tumors using clinically viable formulations remains the primary technical hurdle that prevents the development of siRNA therapy for cancer treatment. Over the past several years, significant effort has been
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99057d1f59b6c4f13bb81b9216377f94
http://europepmc.org/articles/PMC3389750
Zobrazit plný text záznamu
3
Structure of the N-terminal region of Haemophilus influenzae H10017: implications for function
Autor: L, Yu, J, Mack, P, Hajduk, S W, Fesik
Publikováno v: Journal of biomolecular NMR. 20(2)
Haemophilus influenzae is a gram-negative pathogen that causes infections ranging from asymptomatic colonization of the human upper respiratory tract to serious invasive diseases such as meningitis. Although the genome of Haemophilus influenzae has b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9ce21fbad9f0e4101c38e9e66555ce88
https://pubmed.ncbi.nlm.nih.gov/11495242
Zobrazit plný text záznamu
4
Solution structure and function of a conserved protein SP14.3 encoded by an essential Streptococcus pneumoniae gene
Autor: L, Yu, A H, Gunasekera, J, Mack, E T, Olejniczak, L E, Chovan, X, Ruan, D L, Towne, C G, Lerner, S W, Fesik
Publikováno v: Journal of molecular biology. 311(3)
Streptococcus pneumoniae is a major human pathogen that causes high mortality and morbidity rates and has developed resistance to many antibiotics. The genome of S. pneumoniae has recently been completely sequenced revealing many genes encoding hypot
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::088895fcf3bee1e5156fb5d1a12453f5
https://pubmed.ncbi.nlm.nih.gov/11493012
Zobrazit plný text záznamu
5
An approach for high-throughput structure determination of proteins by NMR spectroscopy
Autor: A, Medek, E T, Olejniczak, R P, Meadows, S W, Fesik
Publikováno v: Journal of biomolecular NMR. 18(3)
An approach is described for rapidly determining protein structures by NMR that utilizes proteins containing 13C-methyl labeled Val, Leu, and Ile (delta1) and protonated Phe and Tyr in a deuterated background. Using this strategy, the key NOEs that d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::18ac96836151267b32a39342d94a44dc
https://pubmed.ncbi.nlm.nih.gov/11142513
Zobrazit plný text záznamu
6
14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation
Autor: S R, Datta, A, Katsov, L, Hu, A, Petros, S W, Fesik, M B, Yaffe, M E, Greenberg
Publikováno v: Molecular cell. 6(1)
The Bcl-2 homology 3 (BH3) domain of prodeath Bcl-2 family members mediates their interaction with prosurvival Bcl-2 family members and promotes apoptosis. We report that survival factors trigger the phosphorylation of the proapoptotic Bcl-2 family m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d1a0155de2caa289cf1bbf48b88d250f
https://pubmed.ncbi.nlm.nih.gov/10949026
Zobrazit plný text záznamu
8
Stereospecific assignments and chi 1 rotamers for FKBP when bound to ascomycin from 3JH alpha,H beta and 3HN,H beta coupling constants
Autor: R X, Xu, E T, Olejniczak, S W, Fesik
Publikováno v: FEBS letters. 305(2)
3JH alpha,H beta and 3JN,H beta coupling constants were measured for isotopically labeled FKBP when bound to the immunosuppressant, ascomycin, using a 1H-coupled 3D HCCH-TOCSY and 15N-coupled 3D HSQC-TOCSY experiment, respectively. From an analysis o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6832ed693005ba9e6e5598fdf65d029c
https://pubmed.ncbi.nlm.nih.gov/1377648
Zobrazit plný text záznamu
9
Anesthetic steroid mobility in model membrane preparations as examined by high-resolution 1H and 2H NMR spectroscopy
Autor: A, Makriyannis, C M, DiMeglio, S W, Fesik
Publikováno v: Journal of medicinal chemistry. 34(5)
A series of structurally related pregnane analogues which exhibit a wide range of anesthetic potencies were incorporated into unilamellar egg lecithin vesicles and their relative mobilities examined with 1H and 2H high-resolution NMR spectroscopy. Th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0d8731c8fcd71c92d099d10ccd8cdec0
https://pubmed.ncbi.nlm.nih.gov/2033593
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje