Zobrazeno 1 - 8
of 8
pro vyhledávání: '"S W, Curtis"'
Publikováno v:
APMIS. 109:S490-S492
Estrogen receptors (ER) are thought to play a crucial role in development, reproduction, carcinogenesis and normal physiology. Using gene targeting techniques, we have produced lines of transgenic mice homozygous for the disrupted ERα gene (αERKO)
Publikováno v:
In vitro cellulardevelopmental biology. Animal. 34(8)
Examination of estrogen-responsive processes in cell culture is used to investigate hormonal influence on cancer cell growth and gene expression. Most experimental studies have used breast cancer cell lines, in particular MCF7 cells, to investigate e
Publikováno v:
Scopus-Elsevier
Certain types of estrogenic compounds have been shown to have tissue-specific actions. In addition, some tissues may exhibit differential gene regulation by agonists and antagonists. Our previous studies using structurally modified estrogenic molecul
Autor:
K S, Korach, J F, Couse, S W, Curtis, T F, Washburn, J, Lindzey, K S, Kimbro, E M, Eddy, S, Migliaccio, S M, Snedeker, D B, Lubahn, D W, Schomberg, E P, Smith
Publikováno v:
Recent progress in hormone research. 51
The estrogen receptor (ER) is thought to play a crucial role in the regulation of many life processes, including development, reproduction and normal physiology. Because there have been no known mutations of the estrogen receptor in normal tissue of
Publikováno v:
Journal of biochemistry. 116(4)
We previously showed that the 9 S estrogen receptor (ER) could be reconstituted from purified ER and purified heat shock protein 90 (hsp 90). So, we investigated the role of hsp 90 in the binding of purified ER to an estrogen responsive element (ERE)
Publikováno v:
The Journal of biological chemistry. 268(14)
The DNA-binding domain of the mouse uterine estrogen receptor (ER) was characterized using site-specific polyclonal antibodies. The peptides used as antigens have sequences corresponding to amino acids 185-199 and 227-245, the two zinc finger regions
Publikováno v:
Scopus-Elsevier
The mouse estrogen receptor (mER) exhibits ligand stereochemical specificity for indenestrol A (IA), a stilbestrol estrogen. IA has a chiral C3 methyl group, and the mER preferentially binds the S-enantiomer (IA-S), resulting in elevated biological a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed5251b0e277c7b528fbeb2482b7545d
http://www.scopus.com/inward/record.url?eid=2-s2.0-0029895333&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0029895333&partnerID=MN8TOARS
Autor:
Kenneth S. Korach, K Kauser, Dennis B. Lubahn, J. F. Couse, A D Freay, D.A. Sukovich, G M Rubanyi, S W Curtis, G Burton
Publikováno v:
Scopus-Elsevier
The present study was designed to test the hypothesis that estrogen receptors (ER) in the blood vessel wall play a role in the modulation of the release of endothelium-derived nitric oxide (EDNO). Both basal and stimulated release of EDNO were determ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d0dbf58f77cfbc457655070a4226fc
http://www.scopus.com/inward/record.url?eid=2-s2.0-0030962333&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0030962333&partnerID=MN8TOARS