The Plasmodium falciparum histone methyltransferase PfSET10 is dispensable for the regulation of antigenic variation and gene expression in blood-stage parasites

Autor: Matthias Wyss, Abhishek Kanyal, Igor Niederwieser, Richard Bartfai, Till S. Voss

Publikováno v: mSphere, Vol 9, Iss 11 (2024)

ABSTRACT The malaria parasite Plasmodium falciparum employs antigenic variation of the virulence factor P. falciparum erythrocyte membrane protein 1 (PfEMP1) to escape adaptive immune responses during blood infection. Antigenic variation of PfEMP1 oc

Externí odkaz: https://doaj.org/article/0caf02a1ac834e9799f7244f9e4df126

Expression of the MSPDBL2 antigen in a discrete subset of Plasmodium falciparum schizonts is regulated by GDV1 but may not be linked to sexual commitment

Autor: Aline Freville, Lindsay B. Stewart, Kevin K. A. Tetteh, Moritz Treeck, Alfred Cortes, Till S. Voss, Sarah J. Tarr, David A. Baker, David J. Conway

Publikováno v: mBio, Vol 15, Iss 5 (2024)

ABSTRACTThe Plasmodium falciparum merozoite surface protein MSPDBL2 is a polymorphic antigen targeted by acquired immune responses, and normally expressed in only a minority of mature schizonts. The potential relationship of MSPDBL2 to sexual commitm

Externí odkaz: https://doaj.org/article/a3c074ac2bf04bf99c760a62f54b71a2

Specimen collection is essential for modern science.

Autor: Michael W Nachman, Elizabeth J Beckman, Rauri Ck Bowie, Carla Cicero, Chris J Conroy, Robert Dudley, Tyrone B Hayes, Michelle S Koo, Eileen A Lacey, Christopher H Martin, Jimmy A McGuire, James L Patton, Carol L Spencer, Rebecca D Tarvin, Marvalee H Wake, Ian J Wang, Anang Achmadi, Sergio Ticul Álvarez-Castañeda, Michael J Andersen, Jairo Arroyave, Christopher C Austin, F Keith Barker, Lisa N Barrow, George F Barrowclough, John Bates, Aaron M Bauer, Kayce C Bell, Rayna C Bell, Allison W Bronson, Rafe M Brown, Frank T Burbrink, Kevin J Burns, Carlos Daniel Cadena, David C Cannatella, Todd A Castoe, Prosanta Chakrabarty, Jocelyn P Colella, Joseph A Cook, Joel L Cracraft, Drew R Davis, Alison R Davis Rabosky, Guillermo D'Elía, John P Dumbacher, Jonathan L Dunnum, Scott V Edwards, Jacob A Esselstyn, Julián Faivovich, Jon Fjeldså, Oscar A Flores-Villela, Kassandra Ford, Jérôme Fuchs, Matthew K Fujita, Jeffrey M Good, Eli Greenbaum, Harry W Greene, Shannon Hackett, Amir Hamidy, James Hanken, Tri Haryoko, Melissa Tr Hawkins, Lawrence R Heaney, David M Hillis, Bradford D Hollingsworth, Angela D Hornsby, Peter A Hosner, Mohammad Irham, Sharon Jansa, Rosa Alicia Jiménez, Leo Joseph, Jeremy J Kirchman, Travis J LaDuc, Adam D Leaché, Enrique P Lessa, Hernán López-Fernández, Nicholas A Mason, John E McCormack, Caleb D McMahan, Robert G Moyle, Ricardo A Ojeda, Link E Olson, Chan Kin Onn, Lynne R Parenti, Gabriela Parra-Olea, Bruce D Patterson, Gregory B Pauly, Silvia E Pavan, A Townsend Peterson, Steven Poe, Daniel L Rabosky, Christopher J Raxworthy, Sushma Reddy, Alejandro Rico-Guevara, Awal Riyanto, Luiz A Rocha, Santiago R Ron, Sean M Rovito, Kevin C Rowe, Jodi Rowley, Sara Ruane, David Salazar-Valenzuela, Allison J Shultz, Brian Sidlauskas, Derek S Sikes, Nancy B Simmons, Melanie L J Stiassny, Jeffrey W Streicher, Bryan L Stuart, Adam P Summers, Jose Tavera, Pablo Teta, Cody W Thompson, Robert M Timm, Omar Torres-Carvajal, Gary Voelker, Robert S Voss, Kevin Winker, Christopher Witt, Elizabeth A Wommack, Robert M Zink

Publikováno v: PLoS Biology, Vol 21, Iss 11, p e3002318 (2023)

Natural history museums are vital repositories of specimens, samples and data that inform about the natural world; this Formal Comment revisits a Perspective that advocated for the adoption of compassionate collection practices, querying whether it w

Externí odkaz: https://doaj.org/article/29b3f135891b4b13b5f2dfbb06a42081

What are the barriers and facilitators to effective health promotion in urgent and emergency care? A systematic review

Autor: B. Schofield, U. Rolfe, S. McClean, R. Hoskins, S. Voss, J. Benger

Publikováno v: BMC Emergency Medicine, Vol 22, Iss 1, Pp 1-13 (2022)

Abstract Background There are potential health gains such as reducing early deaths, years spent in ill-health and costs to society and the health and care system by encouraging NHS staff to use encounters with patients to help individuals significant

Externí odkaz: https://doaj.org/article/22178fbd011945e9ab28155a560c2c68

Plasmodium falciparum Sexual Commitment Rate Variation among Clinical Isolates and Diverse Laboratory-Adapted Lines

Autor: Lindsay B. Stewart, Aline Freville, Till S. Voss, David A. Baker, Gordon A. Awandare, David J. Conway

Publikováno v: Microbiology Spectrum, Vol 10, Iss 6 (2022)

ABSTRACT Asexual blood-stage malaria parasites must produce sexual progeny to infect mosquitoes. It is important to understand the scope and causes of intraspecific variation in sexual commitment rates, particularly for the major human parasite P. fa

Externí odkaz: https://doaj.org/article/c945b530d1bd487fa6c592d91ace00d6