Výsledky vyhledávání

Expression of 11 beta-hydroxysteroid dehydrogenase in rat osteoblastic cells: pre-receptor regulation of glucocorticoid responses in bone

Autor: L J, Eyre, E H, Rabbitt, R, Bland, S V, Hughes, M S, Cooper, M C, Sheppard, P M, Stewart, M, Hewison

Publikováno v: Journal of cellular biochemistry. 81(3)

11 beta-hydroxysteroid dehydrogenase (11 beta-HSD) acts as a pre-receptor signaling mechanism for corticosteroids by regulating the access of active glucocorticoids to both glucocorticoid (GR) and mineralocorticoid receptors (MR). To examine the rela

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::45f844b60001a0e783bed45aac3d55db
https://pubmed.ncbi.nlm.nih.gov/11255228

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Estrone potentiates myeloid cell differentiation: a role for 17 beta-hydroxysteroid dehydrogenase in modulating hemopoiesis

Autor: J C, Mountford, C M, Bunce, S V, Hughes, M T, Drayson, D, Webb, G, Brown, M, Hewison

Publikováno v: Experimental hematology. 27(3)

Hormones such as 1 alpha, 25-dihydroxy vitamin D3 (D3), all-trans retinoic acid, and 9-cis retinoic acid stimulate differentiation of myeloid progenitor cells via their interaction with specific hormone receptors. However, the sensitivity of cells to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::893ff242f86580560adcd96c9989a382
https://pubmed.ncbi.nlm.nih.gov/10089907

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Differential RNA display identifies novel genes associated with decreased vitamin D receptor expression

Autor: M, Dabrowski, E, Robinson, S V, Hughes, R, Bland, M, Hewison

Publikováno v: Molecular and cellular endocrinology. 142(1-2)

To characterize further the function of the intracellular vitamin D receptor (VDR), we have developed stable transfectant variants of a vitamin D-responsive cell line (U937) which express either decreased or increased numbers of VDR. In this study we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::431179b42afa2bb7628bf1d213eb0e9e
https://pubmed.ncbi.nlm.nih.gov/9783909

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Applicability of various quality-control sera to assay of high-density lipoprotein cholesterol

Autor: D G Bullock, T J N Carter, S V Hughes

Publikováno v: Clinical Chemistry. 26:903-907

Effective internal quality control and external quality assessment of high-density lipoprotein cholesterol assay is made difficult by analyte instability, and the suitability of quality-control sera for this purpose has not been studied. We have ther

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f4367ffc01c8fda84765b32b89780d8
https://doi.org/10.1093/clinchem/26.7.0903

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