Zobrazeno 1 - 10
of 71
pro vyhledávání: '"S V Alekseeva"'
Autor:
S. V. Alekseeva, A. V. Sorokina, A. V. . Volkova, I. A. Miroshkina, K. S. Kachalov, I. V. Alekseev, A. D. Zakharov, A. D. Durnev
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 4, Pp 63-69 (2024)
Relevance. Acute toxicity testing is a common procedure for preclinical safety testing of potential agents. The purpose of this study was to study the acute toxicity of the compound GIZH-272, a new dibenzofuran oxime derivative with anti-ischemic and
Externí odkaz:
https://doaj.org/article/9f3cd64f6b014c02b599645f3bbfa364
Autor:
A. V. Sorokina, S. V. Alekseeva, I. A. Miroshkina, A. V. Volkova, K. S. Kachalov, A. D. Zakharov, I. V. Alekseev, A. D. Durnev
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 1, Pp 51-57 (2023)
Relevance. Assay of acute toxicity is a mandatory step in a preclinical safety study of medicines and pharmaceutical substances. The purpose of this study was to determine the parameters of acute toxicity of the substance GIZH-298. Methods. GIZH-298
Externí odkaz:
https://doaj.org/article/ef86978f9c8a4bdfaae7aaadec7b4c86
Autor:
I. A. Miroshkina, A. V. Sorokina, A. V. Volkova, V. V. Zabrodina, I. V. Alekseev, K. S. Kachalov, A. D. Zakharov, S. V. Alekseeva
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 4, Pp 48-54 (2021)
Assessment of acute toxicity is a necessary stage of preclinical research of the substance GIZh-298. The aim of present research is study of acute toxicity GIZh-298. Methods. GIZh-298 was administered once intraperitoneally to mice at doses 200-330 m
Externí odkaz:
https://doaj.org/article/7bfeef5dee464153a9653469184eb86e
Autor:
S. V. Alekseeva, A. V. Sorokina, A. V. Volkova, V. V. Zabrodina, I. A. Miroshkina, K. S. Kachalov, I. V. Alekseev, A. D. Zaharov
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 4, Pp 41-47 (2021)
Acute toxicity testing is a commonly accepted procedure for preclinical testing of the safety of potential drugs. The compound GIZh-290, which is a derivative of 4-phenylpyrrolidone– 2,6 - dimethylanilide (2-oxo-4-phenylpyrrolidine-1-yl) acetic aci
Externí odkaz:
https://doaj.org/article/db80459bf14e45c7ad27c46238858579
Autor:
A. V. Sorokina, S. V. Alekseeva, I. A. Miroshkina, K. S. Kachalov, A. D. Zaharov, I. V. Alekseev, A. S. Lapizkaya
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 3, Pp 52-60 (2021)
Presents results of a study of subchronic toxicity of homeopathic drug Dantinorm Baby in finished dosage form. The drug in the form of a ready solution was administered daily orally for one month to outbred rats Infanta and chinchilla rabbits at a do
Externí odkaz:
https://doaj.org/article/fac26546a5da461fa378cbaf6f01337d
Autor:
I. A. Miroshkina, A. V. Sorokina, A. V. Volkova, V. V. Zabrodina, K. S. Kachalov, А. D. Zakharov, S. V. Alekseeva, A. S. Lapitskaya
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 1, Pp 34-41 (2020)
Relevance. Assessment of acute toxicity is a necessary stage of preclinical research of a tablets Homeovox homeopathic. The aim of present research is study of acute toxicity Homeovox.Methods. Homeovox was administered once orally and intraperitoneal
Externí odkaz:
https://doaj.org/article/0d65c97bd2a04e20993475f4514ea78d
Autor:
I. A. Miroshkina, A. V. Sorokina, A. V. Volkova, V. V. Zabrodina, K. S. Kachalov, А. D. Zakharov, S. V. Alekseeva, A. S. Lapitskaya
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 1, Pp 42-52 (2020)
Relevance. Assessment of chronic toxicity is a necessary stage of preclinical research a tablets Homeovox homeopathic. The aim of present research is study of chronic toxicity of a tablets Homeovox homeopathic.Methods. Homeovox was administered orall
Externí odkaz:
https://doaj.org/article/9b7189232b07474592048bdcf05c86f9
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 1, Pp 53-58 (2020)
The study of acute and chronic toxicity of the homeopathic preparation syrup Stodal, produced by the Laboratory of Boiron, France, widely used in medical practice as an effective antitussive agent. Stodal with a single intragastric administration to
Externí odkaz:
https://doaj.org/article/cc638ddd1fe04485930a37a47753e841
Autor:
A. V. Sorokina, S. V. Alekseeva, I. A. Miroshkina, V. V. Zabrodina, L. G. Kolik, A. D. Durnev
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 4, Pp 37-44 (2020)
The results of the study of chronic toxicity of the drug formulation of anxiolytic GB-115 are presented. The novel dipeptide in the form of a tablet mass was administered daily orally for 6 months to outbred rats and rabbits of the chinchilla breed a
Externí odkaz:
https://doaj.org/article/df4e3a7673394b2fb23c766a1c7ab3d0
Publikováno v:
Ведомости Научного центра экспертизы средств медицинского применения, Vol 9, Iss 4, Pp 272-279 (2019)
Chronic toxicity studies are an integral part of the overall toxicological evaluation of drug candidates. Biochemical studies of blood and urine serve to describe the general picture of the animal’s condition and to trace the dynamics of laboratory
Externí odkaz:
https://doaj.org/article/fb56c1c2ff484e998144dbcce7f1e84d