Zobrazeno 1 - 8
of 8
pro vyhledávání: '"S V, Tavtigian"'
Autor:
N B, Adey, L, Huang, P A, Ormonde, M L, Baumgard, R, Pero, D V, Byreddy, S V, Tavtigian, P L, Bartel
Publikováno v:
Cancer research. 60(1)
Two-hybrid searches with the tumor suppressor MMAC1/PTEN isolated the proteins hDLG and hMAST205. Further two-hybrid analysis and microtiter plate binding assays localized the sites of interaction to PDZ domains from hDLG and hMAST205 and the PDZ bin
Autor:
I W, Cheney, D E, Johnson, M T, Vaillancourt, J, Avanzini, A, Morimoto, G W, Demers, K N, Wills, P W, Shabram, J B, Bolen, S V, Tavtigian, R, Bookstein
Publikováno v:
Cancer research. 58(11)
Mutated in multiple advanced cancers 1/phosphatase and tensin homologue (MMAC1/PTEN) is a novel tumor suppressor gene candidate located on chromosome 10 that is commonly mutated in human glioblastoma multiforme and several other cancer types. To eval
Autor:
D H, Teng, W L, Perry, J K, Hogan, M, Baumgard, R, Bell, S, Berry, T, Davis, D, Frank, C, Frye, T, Hattier, R, Hu, S, Jammulapati, T, Janecki, A, Leavitt, J T, Mitchell, R, Pero, D, Sexton, M, Schroeder, P H, Su, B, Swedlund, J M, Kyriakis, J, Avruch, P, Bartel, A K, Wong, S V, Tavtigian
Publikováno v:
Cancer research. 57(19)
Mitogen-activated protein kinases function in signal transduction pathways that are involved in controlling key cellular processes in many organisms. A mammalian member of this kinase family, MKK4/JNKK1/SEK1, has been reported to link upstream MEKK1
Autor:
D, Shattuck-Eidens, A, Oliphant, M, McClure, C, McBride, J, Gupte, T, Rubano, D, Pruss, S V, Tavtigian, D H, Teng, N, Adey, M, Staebell, K, Gumpper, R, Lundstrom, M, Hulick, M, Kelly, J, Holmen, B, Lingenfelter, S, Manley, F, Fujimura, M, Luce, B, Ward, L, Cannon-Albright, L, Steele, K, Offit, A, Thomas
Publikováno v:
JAMA. 278(15)
A mutation in the BRCA1 gene may confer substantial risk for breast and/or ovarian cancer. However, knowledge regarding all possible mutations and the relationship between risk factors and mutations is incomplete.To identify BRCA1 mutations and to de
Autor:
D P, Hejlik, L V, Kottickal, H, Liang, J, Fairman, T, Davis, T, Janecki, D, Sexton, W, Perry, S V, Tavtigian, D H, Teng, L, Nagarajan
Publikováno v:
Cancer research. 57(17)
Acquired interstitial or complete losses of chromosome 5 are recurring anomalies associated with preleukemic myelodysplasia and acute myelogenous leukemia with a poor prognosis. Previous studies have delineated a potential myeloid tumor suppressor lo
Autor:
S, Stone, P, Dayananth, P, Jiang, J M, Weaver-Feldhaus, S V, Tavtigian, L, Cannon-Albright, A, Kamb
Publikováno v:
Oncogene. 11(5)
The P15 gene (MTS2) encodes a cyclin-dependent kinase (CDK) inhibitor with considerable sequence identity and biochemical similarity to the CDK inhibitor p16. It is closely linked to the P16 gene (MTS1) and is homozygously deleted in many tumor cell
Publikováno v:
Cancer research. 55(14)
The p16 gene (P16, MTS1, CDKN2) encodes a negative regulator of the cell cycle. Molecular genetic techniques have been used to explore the role of p16 in normal development and cancer. Two transcripts derived from the p16 gene with distinct protein c