Zobrazeno 1 - 5
of 5
pro vyhledávání: '"S V, Diorditsa"'
Publikováno v:
Bulletin of Experimental Biology and Medicine. 128:1226-1228
Positive effect of local treatment with L-lysine-a-oxidase on the course of herpes genital infection was demonstrated on guinea pigs even after the appearance of infection symptoms. In animals treated with L-lysine-a-oxidase, the severity of the dise
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 128(12)
Publikováno v:
Voprosy meditsinskoi khimii. 44(4)
L-lysin-a-oxidase (LO), a fungal enzyme catalysing oxidative deamination of L-lysin, was used for the inhibition of the reproduction of herpes simplex virus type 1 (HSV-1). Antiviral activity of LO was tested in vitro. The expression of viral antigen
Publikováno v:
Voprosy virusologii. 37(4)
The authors prepared 156 mouse hybridomas producing monoclonal (MCA) antibodies to type- and group-specific antigenic determinants of HSV-1 and HSV-2. Seven of them were studied at length by western blot and radioimmunoprecipitation methods. The cell
Publikováno v:
Molekuliarnaia genetika, mikrobiologiia i virusologiia. (10)
Eight recombinant clones were obtained by insertion of BamHI fragments of herpes simplex type I viral DNA into a vector plasmid pUC19o. Of the obtained clones 5 were found to hybridize with herpes simplex type I and 2 viral DNA while 3 clones reveale