Zobrazeno 1 - 5
of 5
pro vyhledávání: '"S Tucker Marrison"'
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76593 (2013)
The tumor suppressor PTEN is now understood to regulate cellular processes at the cytoplasmic membrane, where it classically regulates PI3K signaling, as well as in the nucleus where multiple roles in controlling cell cycle and genome stability have
Externí odkaz:
https://doaj.org/article/dab14f17c0624768883c18e56fb294fc
Autor:
Barry J. Keane, Caroline Yount, Bill X. Wu, Anne M. Bartlett, Alicja Bielawska, Joseph C. Cheng, Michael T. Smith, E. Ellen Jones, Ping Lu, Katherine Young, James S. Norris, Aiping Bai, David T. Marshall, Thomas E. Keane, Thomas H. Beckham, S. Tucker Marrison, Kent Armeson, Xiang Liu, Richard R. Drake
Publikováno v:
Journal of Clinical Investigation. 123:4344-4358
Escape of prostate cancer (PCa) cells from ionizing radiation–induced (IR-induced) killing leads to disease progression and cancer relapse. The influence of sphingolipids, such as ceramide and its metabolite sphingosine 1-phosphate, on signal trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02fda314fbdc632076d126717693f5a7
https://doi.org/10.1172/jci64791
https://doi.org/10.1172/jci64791
Publikováno v:
Current Molecular Medicine. 9:442-458
Tumor hypoxia influences the outcome of treatment with radiotherapy, chemotherapy and even surgery, not only for the treatment of large bulky tumors with extensive necrosis, but also in the treatment of very small primary tumors and recurrences, micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228f1d28c48f23653a132815a03c6e77
https://doi.org/10.2174/156652409788167087
https://doi.org/10.2174/156652409788167087
Non-surgical therapies for human malignancies must negotiate complex cell signaling pathways to impede cancer cell growth, ideally promoting death of cancer cells while sparing healthy tissue. For most of the past half century, medical approaches for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8990df79687002435bde59d6d4a5928b
https://europepmc.org/articles/PMC4203652/
https://europepmc.org/articles/PMC4203652/
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