Zobrazeno 1 - 10
of 2 085
pro vyhledávání: '"S Tsao"'
Autor:
Jeffrey L. Roberson, Christopher J Neylan, Renae Judy, Venexia Walker, Philip S. Tsao, Scott M. Damrauer, Lillias H. Maguire
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Despite being a common urologic disorder with potentially complicated sequela, the genetic background of adult hydrocele has not previously been described. We performed a multi-population genome-wide association study of 363,460 men in the U
Externí odkaz:
https://doaj.org/article/e87e54977cb344158d7452d0fdf596de
Autor:
Shelley Kuang, Kaitlin Chen, Sachin Sayal, Gajeni Prabahan, Mary R. Rabey, Lisa W. Le, Andrew Seto, Frances A. Shepherd, Geoffrey Liu, Penelope Bradbury, Adrian G. Sacher, Jennifer H. Law, Peter Sabatini, Tracy L. Stockley, Ming S. Tsao, Natasha B. Leighl
Publikováno v:
Current Oncology, Vol 31, Iss 8, Pp 4476-4485 (2024)
In advanced non-squamous non-small-cell lung cancer (NSCLC), routine testing with next-generation sequencing (NGS) is recommended to identify actionable genomic alterations (AGAs). The therapeutic implications of repeated NGS testing on synchronous a
Externí odkaz:
https://doaj.org/article/b1046990507e43358bd21c8d115538a3
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Abdominal aortic aneurysm has a high heritability and often co-occurs with other cardiometabolic disorders, suggesting shared genetic susceptibility. We investigate this commonality leveraging recent GWAS studies of abdominal aortic aneurysm
Externí odkaz:
https://doaj.org/article/1c38404b9f5341d390d3624bd3518216
Autor:
Anne S. Tsao, MD, MBA, Ming-Hui Hsieh, MS, Marianna Koczywas, MD, Janet Tu, MD, Jonathan Riess, MD, MS, Tawee Tanvetyanon, MD, Barbara T. Ma, MD, Ying-Qi Zhao, PhD, Mary W. Redman, PhD, Martin J. Edelman, MD, David R. Gandara, MD, Jhanelle E. Gray, MD, Karen L. Kelly, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 12, Pp 100738- (2024)
Introduction: Thymic carcinoma is a rare and aggressive malignancy with few treatment options. Preclinical studies suggested that targeting the angiogenic pathway may be beneficial in this disease. Methods: This randomized phase 2 trial enrolled pati
Externí odkaz:
https://doaj.org/article/7f396844a1284e749b281a3b1ccd70fc
Publikováno v:
JID Innovations, Vol 4, Iss 6, Pp 100299- (2024)
Keloids are abnormal skin growths occurring in a significant portion of the global population. Despite their pervasiveness, the underlying pathophysiology of this scarring process is yet to be fully understood. In this review article, we delve into t
Externí odkaz:
https://doaj.org/article/6baee4a7206d48009077b6a0aeef8885
Autor:
Charles Lu, Mehmet Altan, Apar Pataer, Tina Cascone, Annikka Weissferdt, Jianjun Zhang, Boris Sepesi, Ara A Vaporciyan, Marcelo V Negrao, Hai T Tran, Stephen G Swisher, John V Heymach, Don L Gibbons, Brett W Carter, Jack A Roth, Ferdinandos Skoulidis, Yasir Y Elamin, Xiuning Le, Wayne L Hofstetter, J Jack Lee, Bonnie S Glisson, Myrna C B Godoy, Garrett L Walsh, Jia Wu, Humam Kadara, George R Blumenschein, Heather Y Lin, Nicolas Zhou, William N William, Cheuk H Leung, Frank V Fossella, Anne S Tsao, Jonathan M Kurie, Lauren A Byers, Reza J Mehran, David C Rice, Luisa M Solis Soto
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 10 (2024)
Background Neoadjuvant immune checkpoint inhibitors (ICIs) have improved survival outcomes compared with chemotherapy in resectable non-small cell lung cancer (NSCLC). However, the impact of actionable genomic alterations (AGAs) on the efficacy of ne
Externí odkaz:
https://doaj.org/article/6cabe896ecc5458b81684d743e2ba8f9
Autor:
Colwyn A. Headley, Shalini Gautam, Angelica Olmo‐Fontanez, Andreu Garcia‐Vilanova, Varun Dwivedi, Alyssa Schami, Susan Weintraub, Philip S. Tsao, Jordi B. Torrelles, Joanne Turner
Publikováno v:
Advanced Science, Vol 11, Iss 36, Pp n/a-n/a (2024)
Abstract Tuberculosis (TB), caused by Mycobacterium tuberculosis (M.tb), is a major global health concern, particularly affecting those with weakened immune systems, including the elderly. CD4+ T cell response is crucial for immunity against M.tb, bu
Externí odkaz:
https://doaj.org/article/0dd086a82df94a179d0e656b797beb92
Autor:
Colwyn A. Headley, Shalini Gautam, Angelica Olmo‐Fontanez, Andreu Garcia‐Vilanova, Varun Dwivedi, Anwari Akhter, Alyssa Schami, Kevin Chiem, Russell Ault, Hao Zhang, Hong Cai, Alison Whigham, Jennifer Delgado, Amberlee Hicks, Philip S. Tsao, Jonathan Gelfond, Luis Martinez‐Sobrido, Yufeng Wang, Jordi B. Torrelles, Joanne Turner
Publikováno v:
Advanced Science, Vol 11, Iss 5, Pp n/a-n/a (2024)
Abstract Mitochondrial dysfunction alters cellular metabolism, increases tissue oxidative stress, and may be principal to the dysregulated signaling and function of CD4+ T lymphocytes in the elderly. In this proof of principle study, it is investigat
Externí odkaz:
https://doaj.org/article/155b08ee8fdd4021bcf7f433c2bfd1c0
Autor:
Eleonora Scorletti, Yedidya Saiman, Sookyoung Jeon, Carolin V. Schneider, Delfin G. Buyco, Chelsea Lin, Blanca E. Himes, Clementina A. Mesaros, Marijana Vujkovic, Kate Townsend Creasy, Emma E. Furth, Jeffrey T. Billheimer, Nicholas J. Hand, David E. Kaplan, Kyong-Mi Chang, Philip S. Tsao, Julie A. Lynch, Joseph L. Dempsey, Julia Harkin, Susovon Bayen, Donna Conlon, Marie Guerraty, Michael C. Phillips, Daniel J. Rader, Rotonya M. Carr
Publikováno v:
JHEP Reports, Vol 6, Iss 1, Pp 100902- (2024)
Background & Aims: Non-alcoholic fatty liver disease (NAFLD) is characterised by the accumulation of lipid droplets (LDs) within hepatocytes. Perilipin 2 (PLIN2) is the most abundant protein in hepatic LDs and its expression correlates with intracell
Externí odkaz:
https://doaj.org/article/0f2aac76aa174d06be32dcaf8efba46a
Autor:
Jia Guo, Qing Zhang, Zhidong Li, Min Qin, Jinyun Shi, Yan Wang, Wenjia Ai, Junjie Ju, Makoto Samura, Philip S Tsao, Baohui Xu
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 726 (2024)
Abdominal aortic aneurysm (AAA) is a chronic aortic disease that lacks effective pharmacological therapies. This study was performed to determine the influence of treatment with the gasdermin D inhibitor necrosulfonamide on experimental AAAs. AAAs we
Externí odkaz:
https://doaj.org/article/b82d580b639e4fa5840cc8a5c2247a5d