Zobrazeno 1 - 10
of 115
pro vyhledávání: '"S Thaisrivongs"'
Autor:
D D Ho, P J Pagano, K T Chong, W. G. Tarpley, T J Dueweke, D E Slade, rd R R Gorman, S M Poppe, M Markowitz, S Thaisrivongs, R. R. Hinshaw, H Mo
Publikováno v:
Antimicrobial Agents and Chemotherapy. 41:1058-1063
PNU-140690 is a member of a new class of nonpeptidic human immunodeficiency virus (HIV) protease inhibitors (sulfonamide-containing 5,6-dihydro-4-hydroxy-2-pyrones) discovered by structure-based design. PNU-140690 has excellent potency against a vari
Autor:
S, Thaisrivongs, M N, Janakiraman, K T, Chong, P K, Tomich, L A, Dolak, S R, Turner, J W, Strohbach, J C, Lynn, M M, Horng, R R, Hinshaw, K D, Watenpaugh
Publikováno v:
Journal of Medicinal Chemistry. 39:2400-2410
The low oral bioavailability and rapid biliary excretion of peptide-derived HIV protease inhibitors have limited their utility as potential therapeutic agents. Our broad screening program to discover non-peptidic HIV protease inhibitors previously id
Publikováno v:
ChemInform. 27
Autor:
S. THAISRIVONGS, M. N. JANAKIRAMAN, K.-T. CHONG, P. K. TOMICH, L. A. DOLAK, S. R. TURNER, J. W. STROHBACH, J. C. LYNN, M.-M. HORNG, R. R. HINSHAW, K. D. WATENPAUGH
Publikováno v:
ChemInform. 27
Publikováno v:
ChemInform. 28
Autor:
S, Thaisrivongs, J W, Strohbach
Publikováno v:
Biopolymers. 51(1)
Efforts to develop therapeutically relevant HIV protease inhibitors as medicinal agents in confronting the AIDS crisis have been aided by the wealth of fundamental information acquired during related drug discovery campaigns against other aspartyl pr
Autor:
G E, Padbury, G L, Zipp, F J, Schwende, Z, Zhao, K A, Koeplinger, K T, Chong, T J, Raub, S, Thaisrivongs
Publikováno v:
Pharmaceutical biotechnology. 11
Autor:
S Thaisrivongs, T J Vidmar, M J Ruwart, E D Roberts, Louis N. Martin, T J Kakuk, S R Davio, Kenneth F. Soike, Michael Murphey-Corb, Rudolf P. Bohm
U-75875 inhibits human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus (SIV) proteases and blocks Gag-Pol protein processing and viral maturation and replication in vitro. Rhesus monkeys were treated with vehicle alone or with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74149d7c9ef41251a9f0f60b0d11cf8c
https://europepmc.org/articles/PMC188198/
https://europepmc.org/articles/PMC188198/
Autor:
A M, Mulichak, J O, Hui, A G, Tomasselli, R L, Heinrikson, K A, Curry, C S, Tomich, S, Thaisrivongs, T K, Sawyer, K D, Watenpaugh
Publikováno v:
The Journal of biological chemistry. 268(18)
The crystal structure of human immunodeficiency virus (HIV) type 2 protease has been determined in complexes with peptidic inhibitors Noa-His-Cha psi [CH(OH)CH(OH)]Val-Ile-Amp (U75875) and Qnc-Asn-Cha psi [CH(OH)CH2]Val-Npt(U92163) (where Noa is naph
Publikováno v:
ACS Symposium Series ISBN: 9780841219489
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d697899956987f46a23b5d6fc38a18dd
https://doi.org/10.1021/bk-1991-0456.ch011
https://doi.org/10.1021/bk-1991-0456.ch011