Zobrazeno 1 - 10
of 198
pro vyhledávání: '"S T Ju"'
Autor:
L C Foote, T J Schneider, G M Fischer, J K Wang, B Rasmussen, K A Campbell, D H Lynch, S T Ju, A Marshak-Rothstein, T L Rothstein
Publikováno v:
The Journal of Immunology. 157:1878-1885
CD40 ligand-activated B cells are sensitive targets for CD4+ Th1 effector cells that kill in a Fas-dependent fashion. Susceptibility to apoptosis is counteracted by Ag receptor binding that produces a state of resistance to Fas engagement in otherwis
Publikováno v:
The Journal of Immunology. 154:4302-4308
Exposure of naive CD4+ T lymphocytes to superantigens such as staphylococcal enterotoxin B (SEB) induces a strong proliferative response. Prolonged exposure or subsequent restimulation of the responding T cell population with SEB leads to the apoptot
Publikováno v:
The Journal of Immunology. 151:4371-4382
We have derived a panel of CD4+, TCR-alpha/beta + T cell clones from SJL (H-2s) mice specific for an encephalitogenic determinant of myelin proteolipid protein (PLP) 139-151 (HSLGKWLGHPDKF). All the clones are Ag specific and IAs restricted, but they
Publikováno v:
The Journal of Immunology. 150:2641-2647
Three synthetic peptides, EEYEYE (peptide 1), EEYEYEEEYEYE (peptide 2), and YEEEEY (peptide 3), were tested for their ability to induce common Id that had been previously characterized for murine antibodies specific to random synthetic polymers of gl
Publikováno v:
The Journal of Immunology. 149:1889-1895
Previous studies have demonstrated that murine CD4 Th1 cells lack perforin and use a pathway distinctive from CD8 CTL to express cytotoxicity. Whether the cytotoxic process of Th1 cells can be separated into identifiable stages and how these differen
Publikováno v:
The Journal of Immunology. 147:4027-4034
A novel cytotoxicity, which is normally hidden but unveiled upon interacting with heat-shocked tumor target, has been identified in CD4+ Th1 cells. When TNF-resistant, Ag-presenting tumor targets were heat shocked, the cytotoxicity by specific Th1 cl
Autor:
S T Ju
Publikováno v:
The Journal of Immunology. 146:812-818
When activated with either Con A, a CD3-specific mAb, or Ag-pulsed B lymphoma (LK35.2) cells, CD4 (Th1) clones quickly induce DNA fragmentation in target cells followed by release of 51Cr-labeled intracellular materials. Both activated CD4 clones and
Publikováno v:
Transplantation Proceedings. 31:893-895
Publikováno v:
The Journal of Immunology. 144:610-613
Serum amyloid A (SAA) is an acute phase reactant and the putative precursor of an amyloid fibril protein (AA). During amyloidogenesis in mice, the C-terminal portion of SAA that consists of 28 amino acids is cleaved off to produce the 75 amino acid A
Publikováno v:
The Journal of Immunology. 144:23-31
A TNF (TNF-alpha and TNF-beta)-sensitive target, L929, and two TNF-resistant targets, P815 and LK were used to compare the cytolytic activity among subsets of CD4+ (Th) clones. Cytolytic activity was induced with either Con A, CD3-mAb, or Ag-pulsed L