Zobrazeno 1 - 10
of 455
pro vyhledávání: '"S T Holgate"'
Autor:
S. T. Holgate
Publikováno v:
European Respiratory Review, Vol 16, Iss 104, Pp 78-84 (2007)
Omalizumab, an anti-immunoglobulin E antibody, is indicated in the European Union (EU) as add-on therapy for patients with severe persistent allergic asthma whose symptoms persist, despite receiving optimised treatment with high-dose inhaled corticos
Externí odkaz:
https://doaj.org/article/2826f72045844658b53f58e9162b3ce7
Publikováno v:
Inflammatory Cells and Mediators in Bronchial Asthma ISBN: 9781003068679
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::727e5ec182631f39c19d52cb0ae4c00d
https://doi.org/10.1201/9781003068679-8
https://doi.org/10.1201/9781003068679-8
Publikováno v:
Mediators of Inflammation, Vol 2, Iss 3, Pp 217-223 (1993)
The time course of effect of the B2-receptor agonist kallidin (K) on induced changes of nasal airflow, rhinorrhoea, nasal pain, sneezing and nasal microvascular leakage has been examined and compared with its B2 metabolite agonist bradykinin (B) and
Externí odkaz:
https://doaj.org/article/ad179ee0a30d49d0acb4ab9de08e32a1
Autor:
Marieke Wandel, Jfc Kelly, S. T. Holgate, Hans Michael Haitchi, Donna E. Davies, Elizabeth R. Davies, JA Whitsett
Publikováno v:
Advances in asthma science and treatment.
Background Maternal allergic asthma is a strong risk factor for the development of asthma and airway hyperresponsiveness (AHR) in children. ADAM33, an asthma susceptibility gene, has been associated with AHR and impaired lung function in early life.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef12c75db402a32904b7125f45c5eb31
https://doi.org/10.1136/thorax-2019-btsabstracts2019.136
https://doi.org/10.1136/thorax-2019-btsabstracts2019.136
Publikováno v:
Eosinophils in Allergy and Inflammation ISBN: 9780367812591
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdce17bdd2f86367c7ae73d8cccf3a88
https://doi.org/10.1201/9780367812591-20
https://doi.org/10.1201/9780367812591-20
Autor:
S. T. Holgate
Publikováno v:
European Respiratory Review, Vol 16, Iss 104, Pp 59-60 (2007)
Externí odkaz:
https://doaj.org/article/9c985e87778c4f039bb9eac7c20278af
Autor:
W. W. Busse, S. T. Holgate
The Pathology of Fatal Asthma, Alan L. James and Neil Carroll Bronchoscopy, Anthony J. Frew and Ratko DjukanovicM Bronchoalveolar Lavage in Studies of Asthma, Mark C. Liu and William J. Calhoun Evidence from Induced Sputum, Peter G. Gibson and Freder
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0461a60052cd384041d4133c6f68d7b1
https://doi.org/10.1201/9780203750896
https://doi.org/10.1201/9780203750896
Autor:
HM Haitchi, Marieke Wandel, Jfc Kelly, Elizabeth R. Davies, S. T. Holgate, JA Whitsett, Donna E. Davies
Publikováno v:
Mucosal and microbial drivers of asthma.
Introduction Most asthma has its origin in early life and probably involves gene-environment interactions. The asthma susceptibility gene ADAM33 is associated with bronchial hyperresponsiveness (BHR) and reduced lung function in young children. It en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f5e59a154113e2d67d5e080957fe639
https://doi.org/10.1136/thorax-2018-212555.35
https://doi.org/10.1136/thorax-2018-212555.35
Autor:
Ying Zu, Donna E. Davies, Jfc Kelly, JA Bell, Hans Michael Haitchi, Elizabeth R. Davies, S. T. Holgate, JA Whitsett
Publikováno v:
Mucosal and microbial drivers of asthma.
Rationale ADAM33 is an asthma susceptibility gene that plays a role in both airway remodelling and susceptibility to allergic airways disease. To study the role of ADAM33 in asthma we have exposed an Adam33 Knockout (KO) mouse to a house dust mite (H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::527e51b0b6f3a435417e058a999ad81f
https://doi.org/10.1136/thorax-2018-212555.33
https://doi.org/10.1136/thorax-2018-212555.33
Autor:
Jfc Kelly, Hans Michael Haitchi, Elizabeth R. Davies, Donna E. Davies, S. T. Holgate, X Xu, JA Whitsett
Publikováno v:
Mechanisms of asthma.
Rational A disintegrin and metalloproteinase 33 (ADAM33) was discovered in 2002 as an asthma susceptibility gene. Genetic associations have been made between ADAM33 polymorphisms and asthma disease severity, bronchial hyperresponsivenss (BHR) and rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d2a0cc0236f35b3d84faa1b36b7294a
https://doi.org/10.1136/thoraxjnl-2017-210983.95
https://doi.org/10.1136/thoraxjnl-2017-210983.95