Zobrazeno 1 - 10
of 15
pro vyhledávání: '"S T, Smale"'
Autor:
B S, Cobb, S T, Smale
Publikováno v:
Current topics in microbiology and immunology. 290
The regulatory steps that lead to the differentiation of hematopoietic cells from a multipotential stem cell remain largely unknown. A beginning to the understanding of these steps has come from the study of DNA-binding proteins that are thought to r
Autor:
Bradley S. Cobb, S. T. Smale
Publikováno v:
Molecular Analysis of B Lymphocyte Development and Activation ISBN: 3540230904
The regulatory steps that lead to the differentiation of hematopoietic cells from a multipotential stem cell remain largely unknown. A beginning to the understanding of these steps has come from the study of DNA-binding proteins that are thought to r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd6c028439d262b3c5f2171d7f75185b
https://doi.org/10.1007/3-540-26363-2_3
https://doi.org/10.1007/3-540-26363-2_3
Autor:
S T, Smale
Publikováno v:
Genesdevelopment. 15(19)
To investigate the basis for enhancer–promoter specificity, we compared the ability of enhancers to activate transcription in vivo from core promoters containing either downstream promoter element (DPE) or TATA box motifs. To eliminate position eff
Publikováno v:
The Journal of biological chemistry. 268(9)
The involvement of ATP during transcription initiation from three basic types of RNA polymerase II promoters was investigated. Hydrolysis of the beta-gamma bond of ATP was found to be required for transcription at TATA, initiator, and initiator + TAT
Publikováno v:
The Journal of biological chemistry. 267(4)
Previous studies have identified several biochemical parameters that resolve promoter-specific transcription initiation by RNA polymerase II into distinct steps. We have employed these parameters to compare the mechanisms of initiation mediated throu
Autor:
A, O'Shea-Greenfield, S T, Smale
Publikováno v:
The Journal of biological chemistry. 267(2)
Transcriptional initiator elements and TATA elements are functionally similar, in that both can act in concert with a Sp1-dependent activator element to direct high levels of accurately initiated transcription. In this study, we have used in vitro tr
Publikováno v:
Molecular and Cellular Biology. 5:352-362
We studied RNA polymerase I transcription in cells transfected with a plasmid, prHuTK, containing the herpes simplex virus tk gene fused to a human rRNA promoter. Primer extension analysis of tk RNA isolated from COS cells transfected with prHuTK rev
Publikováno v:
Journal of Biological Chemistry. 261:14369-14372
We covalently bound periodate-oxidized ATP (oATP) to purified simian virus 40 (SV40) large T-antigen and determined the effect of this modification on viral DNA replication and three other biochemical activities of T-antigen. The oATP bound specifica
Autor:
S T, Smale, R, Tjian
Publikováno v:
Molecular and Cellular Biology. 5:352-362
We studied RNA polymerase I transcription in cells transfected with a plasmid, prHuTK, containing the herpes simplex virus tk gene fused to a human rRNA promoter. Primer extension analysis of tk RNA isolated from COS cells transfected with prHuTK rev
Publikováno v:
Molecular and Cellular Biology. 6:227-235
A cell-free RNA polymerase I transcription system was used to evaluate the transcription efficiency of 21 linker scanning mutations that span the human rRNA gene promoter. Our analysis revealed the presence of two major control elements, designated t