Výsledky vyhledávání

Alloimmunization and erythrocyte autoimmunization in transfusion-dependent thalassemia patients of predominantly asian descent

Autor: S T, Singer, V, Wu, R, Mignacca, F A, Kuypers, P, Morel, E P, Vichinsky

Publikováno v: Blood. 96(10)

The development of hemolytic alloantibodies and erythrocyte autoantibodies complicates transfusion therapy in thalassemia patients. The frequency, causes, and prevention of this phenomena among 64 transfused thalassemia patients (75% Asian) were eval

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d8fc21170c6e2cef944286493309b51e
https://pubmed.ncbi.nlm.nih.gov/11405212

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Erythrocytapheresis for chronically transfused children with sickle cell disease: an effective method for maintaining a low hemoglobin S level and reducing iron overload

Autor: S T, Singer, K, Quirolo, K, Nishi, E, Hackney-Stephens, C, Evans, E P, Vichinsky

Publikováno v: Journal of clinical apheresis. 14(3)

Cerebrovascular accident (CVA) is a major complication of sickle cell disease during childhood. Long-term transfusion reduces the hemoglobin S level and generally prevents recurrent stroke, but it also results in progressive iron overload that requir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::97ee916dbbe117cffca6e3877792a2d3
https://pubmed.ncbi.nlm.nih.gov/10540366

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Deferoxamine treatment during pregnancy: is it harmful?

Autor: S T, Singer, E P, Vichinsky

Publikováno v: American journal of hematology. 60(1)

The use of the iron chelator, Deferoxamine (DFO), in pregnant thalassemia women with iron overload has been generally avoided due to fear of its potential teratogenicity. We describe a case of a pregnant thalassemia major patient with iron overload,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::19f5ca03ea4ad79c300e0070689af4f7
https://pubmed.ncbi.nlm.nih.gov/9883802

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T lymphocyte proliferative responses induced by recombinant factor VIII in hemophilia A patients with inhibitors

Autor: S T, Singer, J E, Addiego, D C, Reason, A H, Lucas

Publikováno v: Thrombosis and haemostasis. 76(1)

In this study we sought to determine whether factor VIII-reactive T lymphocytes were present in hemophilia A patients with inhibitor antibodies. Peripheral blood mononuclear cells (MNC) were obtained from 12 severe hemophilia A patients having high t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d76bb7241efacf5ecf879be921edb325
https://pubmed.ncbi.nlm.nih.gov/8819245

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