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Regioselective alkylation at the N4 position of a 3-oxo-1,4-benzodiazepine on solid support

Autor: F E, Ali, C C, Yuan, S T, Ross, L B, Hall

Publikováno v: Molecular diversity. 5(1)

An efficient solid phase regioselective alkylation at the N4 position of a 3-oxo-1,4-benzodiazepine template exemplified by 4-H-2,3,4,5-tetrahydro-7-iodo-3-oxo-1H-1,4-benzodiazepine-2-acetate-polymer ester is described. Further chemical elaboration a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2f463d6fea6fd5ece44fd851c65930e3
https://pubmed.ncbi.nlm.nih.gov/11383487

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Design and characterization of orally active Arg-Gly-Asp peptidomimetic vitronectin receptor antagonist SB 265123 for prevention of bone loss in osteoporosis

Autor: M W, Lark, G B, Stroup, S M, Hwang, I E, James, D J, Rieman, F H, Drake, J N, Bradbeer, A, Mathur, K F, Erhard, K A, Newlander, S T, Ross, K L, Salyers, B R, Smith, W H, Miller, W F, Huffman, M, Gowen

Publikováno v: The Journal of pharmacology and experimental therapeutics. 291(2)

The Arg-Gly-Asp (RGD)-binding integrin alpha(V)beta(3) is highly expressed on osteoclasts and has been proposed to mediate cell-matrix adhesion required for osteoclast-mediated bone resorption. Antagonism of this receptor should prevent stable osteoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3c265c9c299af6bb5e141179d3d2de53
https://pubmed.ncbi.nlm.nih.gov/10525079

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Relationships Between Germanium and Cadmium in the Electrolysis of Zinc Sulphate Solutions

Autor: J. L. Bray, S. T. Ross

Publikováno v: JOM. 3:465-467

The paper provides electrometallurgical data on the problem of germanium removal from zinc sulphate solutions. Germanium traces have caused much concern to the zinc refiner. Confirmatory evidence of interaction between germanium and cadmium is presen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1f7118fac2a06d6799a15076c2906b68
https://doi.org/10.1007/bf03397332

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Chemoprophylaxis for patients with colorectal cancer. Prospective study with five-year follow-up

Autor: M C, Li, S T, Ross

Publikováno v: JAMA. 235(26)

The effectiveness of a short-term fluorouracil chemopophylaxis regimen commencing four to six weeks after "curative" surgery was evaluated in a homogeneous group of 213 patients with colorectal cancer. In stage III disease (Dukes class C), five-year

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::72412f90e546168dea176a32a630f756
https://pubmed.ncbi.nlm.nih.gov/946987

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