Zobrazeno 1 - 6
of 6
pro vyhledávání: '"S T, Moe"'
Publikováno v:
Journal of Medicinal Chemistry. 37:579-585
Naltrindole (1) (NTI) is a highly potent and selective delta-opioid receptor antagonist. In an effort to understand the origin of the high potency, affinity, and selectivity of NTI, we have examined the conformational role of its indolic benzene moie
Publikováno v:
Journal of Biological Chemistry. 268:23055-23058
The enkephalins, dynorphins, and endorphins are endogenous opioids which function as neurotransmitters, neuromodulators, and hormones and are involved in the perception of pain, modulation of behavior, and regulation of autonomic and neuroendocrine f
Autor:
Y. Chien, M. F. Balandrin, S. T. Moe, D. Wells, T. B. Marriott, A. Kierstead, E. Brady, B. VanWagenen, E. G. Delmar, J. L. Raszkiewicz, Alan L. Mueller, Linda D. Artman
Publikováno v:
Amino acids. 19(1)
NPS Pharmaceuticals, Inc. (NPS) has synthesized a series of open-channel blockers with varying potencies at the NMDA receptor. NPS 1506 (Fig. 1) is a moderate affinity antagonist that inhibits NMDA/glycine-induced increases in cytosolic calcium in cu
Publikováno v:
Pharmaceutical research. 15(1)
Twelve synthetic spider toxin analogs were prepared in an effort to better understand the structure-activity relationships of the polyamine portion of argiotoxin-636 (Arg-636), a noncompetitive NMDA receptor (NMDAR) antagonist.The 1,13-diamino-4,8-di
Publikováno v:
Journal of medicinal chemistry. 36(17)
Autor:
G. N. Stowe, Kim D. Janda, P. Silhár, N. R. Silvaggi, M. S. Hixon, S. T. Moe, A. R. Jacobson, J. T. Barbieri, K. N. Allen
Publikováno v:
Synfacts. 2010:0502-0502