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pro vyhledávání: '"S T, Buxton"'
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 288(3)
Cotinine, a major peripheral metabolite of nicotine, has recently been shown to be the most abundant metabolite in rat brain after peripheral nicotine administration. However, little attention has been focused on the contribution of cotinine to the p
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 283(2)
Previous results from our laboratory demonstrated that S(-)nornicotine, a major tobacco alkaloid and an active nicotine metabolite present in the CNS, increases dopamine release from rat striatal slices in a concentration-dependent and calcium-depend