Zobrazeno 1 - 10
of 15
pro vyhledávání: '"S T, Butera"'
Autor:
S T, Butera
Publikováno v:
Methods in molecular medicine. 24
It is critically important that new therapeutic compounds and targets for therapeutic intervention be identified in the battle against the human immunodeficieny virus type 1(HIV-1). Many of the currently existing therapeutic approaches target virus-s
Publikováno v:
Antiviral Chemistry and Chemotherapy. 4:55-63
The development of a reliable and simple system for evaluating compounds that could prevent activation of latent HIV would allow us to devise new therapeutic approaches. These compounds could eventually be used in combination with drugs that are effe
Publikováno v:
The Journal of Immunology. 150:625-634
Using the CD4+ model of chronic HIV-1 infection, OM-10.1, we investigated the influence of TNF-alpha regulatory networks on induced viral expression. Previously, OM-10.1 cultures were characterized to respond to exogenous TNF-alpha, as nearly 100% of
Publikováno v:
The Journal of Immunology. 147:3145-3148
A chronically HIV-1-infected T cell clone (J1.1) derived from Jurkat cells was developed that possesses defects in CD3 signaling. This clone was phenotypically determined to be CD4- and express a reduced surface density of CD3 as compared with a pool
Publikováno v:
Antiviral chemistrychemotherapy. 12
The cellular transcription elongation factor, P-TEFb, and its kinase component, cdk-9, have been implicated in the regulation of HIV-1 transactivation and transcription. We tested a panel of demonstrated cdk-9 kinase inhibitors for the ability to blo
Autor:
S. M. Owen, A. L. Matthews, M. E. Callahan, S. T. Butera, L. E. Chapman, J. Brown, D. D. Weigner, P. A. Sandstrom
Publikováno v:
Journal of the American Veterinary Medical Association. 217(10)
Objective—To examine exposure risks, possibility of zoonosis, and potential disease associations for feline retroviruses among a group of occupationally exposed individuals. Design—Unlinked voluntary cross-sectional epidemiologic survey. Sample P
Publikováno v:
Journal of virology. 74(1)
Antigens derived from host cells are detectable in the envelope of human immunodeficiency virus type 1 (HIV-1) and result in a distinctive viral phenotype reflecting that of the host cell. An immunomagnetic capture assay targeting discriminatory host
Publikováno v:
Blood. 89(5)
Controversy exists concerning the preferential infection and replication of human immunodeficiency virus-1 (HIV-1) within naive (CD45RA+) and memory (CD45RO+) subsets of CD4+ lymphocytes. To explore the susceptibility of these subsets to HIV-1 infect
Publikováno v:
Archives of virology. 142(6)
Because of an inherent dependence on host cell second and third messenger signaling pathways for activation of HIV-1 expression, a potential exists for a relationship between the induction of latent HIV-1 and cell-cycle-related events. To investigate
Publikováno v:
AIDS (London, England). 7(7)
To examine the inter-relationship between HIV-1 infection and the cell surface receptors for tumor necrosis factor (TNF)-alpha, an immunoregulatory cytokine that can enhance HIV-1 replication.Infected promyelocytic and promonocytic cells were examine