Zobrazeno 1 - 10
of 2 031
pro vyhledávání: '"S Sutherland"'
Autor:
P Tooz-Hobson, S Sutherland, C Amundsen, R McCrery, E Kean, S De Wachter, K Benson, F Martens, K Ferrrante, O Padron, L Giusto, K Robertson, A Pezzella, R Dmochowski, K Aharonson-Raz, S Baruch, J Heesakkers, A Digesu
Publikováno v:
Continence, Vol 7, Iss , Pp 100937- (2023)
Externí odkaz:
https://doaj.org/article/a7dac6da2f5c4f0a8874de3fed844200
Autor:
Zahra Shakeran, Jaleh Varshosaz, Mehrnaz Keyhanfar, Hossein Mohammad-Beigi, Karim Rahimi, Duncan S. Sutherland
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 50, Iss 1, Pp 29-39 (2022)
Co-delivery of anticancer drugs and biologics can provide synergetic effects and outperform single delivery therapies. Here, a nanoparticle (NP) system for co-delivery of methotrexate (MTX) and STAT3 siRNA has been developed and tested in vitro. Meso
Externí odkaz:
https://doaj.org/article/0fae37188755466db48397df1d4e0bb6
Autor:
Hossein Mohammad-Beigi, Yuya Hayashi, Christina Moeslund Zeuthen, Hoda Eskandari, Carsten Scavenius, Kristian Juul-Madsen, Thomas Vorup-Jensen, Jan J. Enghild, Duncan S. Sutherland
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Understanding the biological identity of nanoparticles has mainly focused on the hard protein corona with the soft corona largely overlooked. Here, using click-chemistry, the authors report on a capture system for the identification of the soft coron
Externí odkaz:
https://doaj.org/article/35b5008eb572436fb96cdcb7e530c5c0
Autor:
W. van Loon, M. P. Gomez, D. Jobe, K. L. M. C. Franken, T. H. M. Ottenhoff, M. Coninx, L. Kestens, J. S. Sutherland, B. Kampmann, L. D. Tientcheu
Publikováno v:
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background Interferon-γ release assays (IGRA) with Resuscitation promoting factor (Rpf) proteins enhanced tuberculosis (TB) screening and diagnosis in adults but have not been evaluated in children. Children often develop paucibacillary TB
Externí odkaz:
https://doaj.org/article/62c957adf37148d096e558e1bb4b2d3d
Autor:
Stuart Meier, James A Seddon, Elizna Maasdorp, Léanie Kleynhans, Nelita du Plessis, Andre G Loxton, Stephanus T Malherbe, Daniel E Zak, Ethan Thompson, Fergal J Duffy, Stefan H E Kaufmann, Tom H M Ottenhoff, Thomas J Scriba, Sara Suliman, Jayne S Sutherland, Jill Winter, Helena Kuivaniemi, Gerhard Walzl, Gerard Tromp, GC6-74 Consortium, Catalysis TB Biomarkers Consortium
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0278295 (2022)
Mycobacterium tuberculosis (M.tb) causes tuberculosis (TB) and remains one of the leading causes of mortality due to an infectious pathogen. Host immune responses have been implicated in driving the progression from infection to severe lung disease.
Externí odkaz:
https://doaj.org/article/a9c3c19a74ea47aa90537128b591d9f8
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/df52ceba03f540bf9fa7b85d18b26eee
Autor:
Lydia Medawar, Hatimi Mohd Tukiman, Georgetta Mbayo, Simon Donkor, Olumuyiwa Owolabi, Jayne S. Sutherland
Publikováno v:
Immunity, Inflammation and Disease, Vol 7, Iss 4, Pp 260-270 (2019)
Abstract Background Tuberculosis (TB) is the leading cause of death from a single infectious agent worldwide. The immune system is capable of clearing the pathogen before establishment of latent infection but the mechanisms for this are not yet under
Externí odkaz:
https://doaj.org/article/96a1b9eaffa9462780034e5d135d44c9
Autor:
Caleb Nwongbouwoh Muefong, Olumuyiwa Owolabi, Simon Donkor, Salome Charalambous, Joseph Mendy, Isatou C. M. Sey, Abhishek Bakuli, Andrea Rachow, Christof Geldmacher, Jayne S. Sutherland
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundThe inflammatory response to Mycobacterium tuberculosis results in variable degrees of lung pathology during active TB (ATB) with central involvement of neutrophils. Little is known about neutrophil-derived mediators and their role in disea
Externí odkaz:
https://doaj.org/article/0c7071691b8a419991d0a4a023eb58fa
Autor:
Hossein Eyni, Sadegh Ghorbani, Hojjatollah Nazari, Marziyeh Hajialyani, Sajad Razavi Bazaz, Mahdi Mohaqiq, Majid Ebrahimi Warkiani, Duncan S Sutherland
Publikováno v:
Journal of Tissue Engineering, Vol 12 (2021)
In modern life, several factors such as genetics, exposure to toxins, and aging have resulted in significant levels of male infertility, estimated to be approximately 18% worldwide. In response, substantial progress has been made to improve in vitro
Externí odkaz:
https://doaj.org/article/bac7f3d7165a4705a6d6fb854ba7e44c
Autor:
Hamish S. Sutherland, Peter J. Choi, Guo-Liang Lu, Anna C. Giddens, Amy S. T. Tong, Scott G. Franzblau, Christopher B. Cooper, Brian D. Palmer, William A. Denny
Publikováno v:
Pharmaceuticals, Vol 15, Iss 9, p 1125 (2022)
Pyrazolo[1,5-a]pyrimidines have been reported as potent inhibitors of mycobacterial ATP synthase for the treatment of Mycobacterium tuberculosis (M.tb). In this work, we report the design and synthesis of approximately 70 novel 3,5-diphenyl-N-(pyridi
Externí odkaz:
https://doaj.org/article/4840706fc3a44c07b8ab3fa39c285356