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Elektronická kniha

Autor: Malcolm S. Southwood

This highly recommended book,'You and Your Mobile Home', is a fascinating insight into the dynamics of health and happiness through belief and emotion. Malcolm S. Southwood has, after almost 40 years of practical and spiritual experience, managed to

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Elektronická kniha

Where the Soul Flies

Autor: Malcolm S. Southwood

In his book, Where the Soul Flies, Malcolm Southwood describes what to expect when we leave this world to move into the next one. He uses his own experience of out-of-body states to explain a process we will all come to know at some future date. In a

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The Self-Directed T Cell Repertoire Against Mouse Lysozyme Reflects the Influence of the Hierarchy of Its Own Determinants and Can Be Engaged by a Foreign Lysozyme

Autor: K D, Moudgil, S, Southwood, A, Ametani, K, Kim, A, Sette, E E, Sercarz

Publikováno v: The Journal of Immunology. 163:4232-4237

The T cell repertoire is shaped by the processes of positive and negative selection. We have previously shown that mice are tolerant to a native self-Ag, mouse lysozyme (ML), but they respond vigorously when challenged with different ML peptides (“

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d0d8bd621b3e8852a7d45162ad61e5
https://doi.org/10.4049/jimmunol.163.8.4232

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Several Common HLA-DR Types Share Largely Overlapping Peptide Binding Repertoires

Autor: S, Southwood, J, Sidney, A, Kondo, M F, del Guercio, E, Appella, S, Hoffman, R T, Kubo, R W, Chesnut, H M, Grey, A, Sette

Publikováno v: The Journal of Immunology. 160:3363-3373

The peptide binding specificities of HLA-DRB1*0401, DRB1*0101, and DRB1*0701 have been analyzed by the use of large collections of synthetic peptides corresponding to naturally occurring sequences. The results demonstrated that nearly all peptides bi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddfe3e7abeda2ba6d12dd4868eef3b18
https://doi.org/10.4049/jimmunol.160.7.3363

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Degenerate and promiscuous recognition by CTL of peptides presented by the MHC class I A3-like superfamily: implications for vaccine development

Autor: S C Threlkeld, P A Wentworth, S A Kalams, B M Wilkes, D J Ruhl, E Keogh, J Sidney, S Southwood, B D Walker, A Sette

Publikováno v: The Journal of Immunology. 159:1648-1657

Recent data demonstrate that HLA class I alleles can be grouped into superfamilies based on similarities of their peptide-binding motifs. In this study, we have tested the immunogenicity and antigenicity of peptides capable of degenerate binding to m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe2ea1b482e8f318d60f02371abddb6e
https://doi.org/10.4049/jimmunol.159.4.1648

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Uncovering subdominant cytotoxic T-lymphocyte responses in lymphocytic choriomeningitis virus-infected BALB/c mice

Autor: Rafi Ahmed, S Southwood, J Sidney, J Alexander, R. J. Concepcion, R W Chesnut, R G van der Most, Alessandro Sette, C Oseroff

Publikováno v: Journal of Virology. 71:5110-5114

The cytotoxic T-lymphocyte response against lymphocytic choriomeningitis virus (LCMV) in BALB/c mice is predominantly directed against a single, Ld-restricted epitope in the viral nucleoprotein (residues 118 to 126). To investigate whether any Kd/Dd-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a038a3e63212ed8d8b95dce17241bf75
https://doi.org/10.1128/jvi.71.7.5110-5114.1997

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Determinants of T cell reactivity to the Mycobacterium leprae GroES homologue

Autor: J Kim, A Sette, S Rodda, S Southwood, P A Sieling, V Mehra, J D Ohmen, J Oliveros, E Appella, Y Higashimoto, T H Rea, B R Bloom, R L Modlin

Publikováno v: The Journal of Immunology. 159:335-343

The 10-kDa protein Ag of Mycobacterium leprae, a human GroES hsp10 cognate, is a major T cell Ag in human leprosy infection. We investigated the mechanism for T cell responsiveness to this Ag according to the trimolecular interaction between T cell,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4f3cc03347526efdafa5ec3d69db6e80
https://doi.org/10.4049/jimmunol.159.1.335

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Identification of subdominant CTL epitopes of the GP100 melanoma-associated tumor antigen by primary in vitro immunization with peptide-pulsed dendritic cells

Autor: V Tsai, S Southwood, J Sidney, K Sakaguchi, Y Kawakami, E Appella, A Sette, E Celis

Publikováno v: The Journal of Immunology. 158:1796-1802

The gp100 melanoma-associated tumor Ag was selected as a model system to study the diversity of human antitumor cytotoxic T cell responses. First, peptides corresponding to dominant gp100 HLA-A2.1-restricted CTL epitopes were tested using lymphocytes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2a89c2d75de01b038a49d2959e845bab
https://doi.org/10.4049/jimmunol.158.4.1796

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Immunodominance analysis of CTL responses to influenza PR8 virus reveals two new dominant and subdominant Kb-restricted epitopes

Autor: A Vitiello, L Yuan, R W Chesnut, J Sidney, S Southwood, P Farness, M R Jackson, P A Peterson, A Sette

Publikováno v: The Journal of Immunology. 157:5555-5562

In the present study, a systematic analysis of the influenza (Flu) PR8 determinants recognized by H-2b mice was undertaken. A single Db-restricted immunodominant epitope (NP(366)) was previously known in this system. Twenty-three different Flu PR8-de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::02331f2a77763026f37e2dcdc6d22868
https://doi.org/10.4049/jimmunol.157.12.5555

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