Zobrazeno 1 - 10
of 197
pro vyhledávání: '"S Shankman"'
Autor:
Sanja Arandjelovic, Justin S. A. Perry, Ming Zhou, Adam Ceroi, Igor Smirnov, Scott F. Walk, Laura S. Shankman, Isabelle Cambré, Suna Onengut-Gumuscu, Dirk Elewaut, Thomas P. Conrads, Kodi S. Ravichandran
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Osteoporosis and bone fractures affect millions of patients worldwide and are often due to increased bone resorption. Here the authors identify the cytoplasmic protein ELMO1 as an important ‘signaling node’ promoting the bone resorption function
Externí odkaz:
https://doaj.org/article/c891c2231fd74501bad6e2537e8eceb6
Autor:
Claudia M. Rival, Wenhao Xu, Laura S. Shankman, Sho Morioka, Sanja Arandjelovic, Chang Sup Lee, Karen M. Wheeler, Ryan P. Smith, Lisa B. Haney, Brant E. Isakson, Scott Purcell, Jeffrey J. Lysiak, Kodi S. Ravichandran
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Izumo and Juno are receptors on sperm and eggs respectively required for fusion, but other factors for sperm-egg fusion are poorly studied. Here, the authors report that phosphatidylserine, found mainly on cells marked for death, is also present on m
Externí odkaz:
https://doaj.org/article/89356b6243dc4c859d4c2eaf9ae0cf51
Autor:
Rebecca A. Deaton, Gamze Bulut, Vlad Serbulea, Anita Salamon, Laura S. Shankman, Anh Tram Nguyen, Gary K. Owens
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 43:203-211
Background: The Myh11 promoter is extensively used as a smooth muscle cell (SMC) Cre-driver and is regarded as the most restrictive and specific promoter available to study SMCs. Unfortunately, in the existing Myh11-CreER T2 mouse, the transgene was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::370b0f9a1b5a20beaac9b0b802ed7863
https://doi.org/10.1161/atvbaha.122.318160
https://doi.org/10.1161/atvbaha.122.318160
Akademický článek
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Autor:
Rebecca A, Deaton, Gamze, Bulut, Vlad, Serbulea, Anita, Salamon, Laura S, Shankman, Anh Tram, Nguyen, Gary K, Owens
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology.
TheAWe generated and validated the function of an autosomal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::32126d8478295fccad73da7f0e6af990
https://pubmed.ncbi.nlm.nih.gov/36519470
https://pubmed.ncbi.nlm.nih.gov/36519470
Autor:
Laura S. Shankman, Ming-Ming Zhou, Kodi S. Ravichandran, Scott F. Walk, Sanja Arandjelovic, Dirk Elewaut, Adam Ceroi, Thomas P. Conrads, Igor Smirnov, Isabelle Cambré, Suna Onengut-Gumuscu, Justin S. A. Perry
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
NATURE COMMUNICATIONS
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
NATURE COMMUNICATIONS
Osteoporosis affects millions worldwide and is often caused by osteoclast induced bone loss. Here, we identify the cytoplasmic protein ELMO1 as an important ‘signaling node’ in osteoclasts. We note that ELMO1 SNPs associate with bone abnormalitie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce83cac9e6f2548d521dea180ef3572
http://europepmc.org/articles/PMC8371122
http://europepmc.org/articles/PMC8371122
Publikováno v:
BHI
Cell quantification in 3D atherosclerotic plaque immunofluorescent images is critical in improving understanding of plaque composition and possibly preventing rupture. Manual annotation of these cells is required to build predictive models that class
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37e1a295c794291aecca28126ab7d6c9
https://doi.org/10.1109/bhi50953.2021.9508607
https://doi.org/10.1109/bhi50953.2021.9508607
Autor:
Laura S. Shankman, Karen Wheeler, Claudia Rival, Lisa B. Haney, Jeffrey J. Lysiak, Sho Morioka, Sanja Arandjelovic, Ryan P. Smith, Kodi S. Ravichandran, Wenhao Xu, Brant E. Isakson, Chang Sup Lee, Scott Purcell
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
NATURE COMMUNICATIONS
Nature Communications
NATURE COMMUNICATIONS
Fertilization is essential for species survival. Although Izumo1 and Juno are critical for initial interaction between gametes, additional molecules necessary for sperm:egg fusion on both the sperm and the oocyte remain to be defined. Here, we show t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::977e6af026c9a6ad432f636746f12a12
http://link.springer.com/article/10.1038/s41467-019-12406-z
http://link.springer.com/article/10.1038/s41467-019-12406-z
Autor:
Sanja Arandjelovic, Kodi S. Ravichandran, W. Britt Evans, Laura S. Shankman, Kristen K. Penberthy, Hervé Agaisse, Richard S. Blumberg, Samantha T. Fleury
Publikováno v:
Curr Biol
Summary Apoptotic cells are quickly and efficiently engulfed and removed via the process of efferocytosis by either professional phagocytes, such as macrophages, or non-professional phagocytes, including epithelial cells. 1 , 2 In addition to debris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0238bfa342f10c51593dd197e89ef2
https://europepmc.org/articles/PMC8281366/
https://europepmc.org/articles/PMC8281366/
Autor:
Liang Guo, Gabriel F. Alencar, Gary K. Owens, Xenia Bradley, Laura S. Shankman, Alexandra A. C. Newman, Anita Salamon, Sohel Shamsuzzaman, Aloke V. Finn, Vlad Serbulea, Richard A. Baylis, Rebecca A. Deaton, Mahima S. Reddy, Renu Virmani, Santosh Karnewar, Katherine Owsiany, Olga A. Cherepanova
Publikováno v:
Nature metabolism
Stable atherosclerotic plaques are characterized by a thick, extracellular matrix-rich fibrous cap populated by protective ACTA2+ myofibroblast (MF)-like cells, assumed to be almost exclusively derived from smooth muscle cells (SMCs). Herein, we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4846e78dc09ec942c93e1b7c5668ff5
https://pubmed.ncbi.nlm.nih.gov/33619382
https://pubmed.ncbi.nlm.nih.gov/33619382