Zobrazeno 1 - 10 of 14 pro vyhledávání: '"S Scott Perry"'
1
Akademický článek
Interplay between H1N1 influenza a virus infection, extracellular and intracellular respiratory tract pH, and host responses in a mouse model.
Autor: Faten A Okda, S Scott Perry, Richard J Webby, Charles J Russell
Publikováno v: PLoS ONE, Vol 16, Iss 5, p e0251473 (2021)
During influenza A virus (IAV) entry, the hemagglutinin (HA) protein is triggered by endosomal low pH to undergo irreversible structural changes that mediate membrane fusion. HA proteins from different isolates vary in the pH at which they become act
Externí odkaz: https://doaj.org/article/fd5ce1bbbc764df4badfa0592590b8cf
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2
Akademický článek
Genome editing of HBG1 and HBG2 to induce fetal hemoglobin
Autor: Jean-Yves Métais, Phillip A. Doerfler, Thiyagaraj Mayuranathan, Daniel E. Bauer, Stephanie C. Fowler, Matthew M. Hsieh, Varun Katta, Sagar Keriwala, Cicera R. Lazzarotto, Kevin Luk, Michael D. Neel, S. Scott Perry, Samuel T. Peters, Shaina N. Porter, Byoung Y. Ryu, Akshay Sharma, Devlin Shea, John F. Tisdale, Naoya Uchida, Scot A. Wolfe, Kaitly J. Woodard, Yuxuan Wu, Yu Yao, Jing Zeng, Shondra Pruett-Miller, Shengdar Q. Tsai, Mitchell J. Weiss
Publikováno v: Blood Advances, Vol 3, Iss 21, Pp 3379-3392 (2019)
Abstract: Induction of fetal hemoglobin (HbF) via clustered regularly interspaced short palindromic repeats/Cas9–mediated disruption of DNA regulatory elements that repress γ-globin gene (HBG1 and HBG2) expression is a promising therapeutic strate
Externí odkaz: https://doaj.org/article/d8bdc8c4db524cf3ab90d0385b570174
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4
Interplay between H1N1 influenza a virus infection, extracellular and intracellular respiratory tract pH, and host responses in a mouse model
Autor: Richard J. Webby, Charles J. Russell, S. Scott Perry, Faten A. Okda
Publikováno v: PLoS ONE
PLoS ONE, Vol 16, Iss 5, p e0251473 (2021)
During influenza A virus (IAV) entry, the hemagglutinin (HA) protein is triggered by endosomal low pH to undergo irreversible structural changes that mediate membrane fusion. HA proteins from different isolates vary in the pH at which they become act
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca176403eb7efb35752c9000eea1b811
https://pubmed.ncbi.nlm.nih.gov/33979408
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6
Regulation of Lymphocyte Development by Cell-Type-Specific Interpretation of Notch Signals
Autor: Lei Nie, Xiao Hong Sun, Ying Zhao, Paul W. Kincade, Michael A. Farrar, S. Scott Perry, Jiaxue Huang
Publikováno v: Molecular and Cellular Biology. 28:2078-2090
Notch signaling pathways exert diverse biological effects depending on the cellular context where Notch receptors are activated. How Notch signaling is integrated with environmental cues is a central issue. Here, we show that Notch activation acceler
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d65d34fbcdcdd6624b9069e3cc3ed5
https://doi.org/10.1128/mcb.00844-07
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7
Id1, but not Id3, directs long-term repopulating hematopoietic stem-cell maintenance
Autor: Ying Zhao, S. Scott Perry, Zhong Huang, Shawn W. Cochrane, Xiao Hong Sun, Lei Nie
Publikováno v: Blood. 110:2351-2360
E-proteins are widely expressed basic helix-loop-helix (HLH) transcription factors that regulate differentiation in many cell lineages, including lymphoid, muscle, and neuronal cells. E-protein function is controlled by HLH inhibitors such as Id and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0a54b0778c704982aaf56989e672ff
https://doi.org/10.1182/blood-2007-01-069914
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8
Interferon-producing killer dendritic cells (IKDCs) arise via a unique differentiation pathway from primitive c-kitHiCD62L+ lymphoid progenitors
Autor: Rosana Pelayo, Karla P. Garrett, Paul W. Kincade, Xiao Hong Sun, Xinrong Chen, S. Scott Perry, Barbara L. Kee, Robert S. Welner
Publikováno v: Blood. 109:4825-4931
Interferon-producing killer dendritic cells (IKDCs) have only recently been described and they share some properties with plasmacytoid dendritic cells (pDCs). We now show that they can arise from some of the same progenitors. However, IKDCs expressed
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0b8cf50a8fc1669f0577edfea990ef3
https://doi.org/10.1182/blood-2006-08-043810
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9
Apoptosis-Inducing-Factor-Dependent Mitochondrial Function Is Required for T Cell but Not B Cell Function
Autor: Oliver E. Sturm, Paul G. Thomas, Christopher P. Dillon, Scott A. Brown, Douglas R. Green, Sharon Frase, Giovanni Quarato, Sandra Milasta, Laura J. Janke, Katherine Verbist, S. Scott Perry, Taylor L. Brewer
Publikováno v: Immunity. 44(1)
The role of apoptosis inducing factor (AIF) in promoting cell death versus survival remains controversial. We report that the loss of AIF in fibroblasts led to mitochondrial electron transport chain defects and loss of proliferation that could be res
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9abbbbd7d610ec223fdb474e67b3ed5b
https://pubmed.ncbi.nlm.nih.gov/26789917
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10
Primitive Lymphoid Progenitors in Bone Marrow with T Lineage Reconstituting Potential
Autor: Paul W. Kincade, Xiao Hong Sun, S. Scott Perry, Taku Kouro, Robert S. Welner
Publikováno v: The Journal of Immunology. 177:2880-2887
Multiple subsets of the bone marrow contain T cell precursors, but it remains unclear which is most likely to replenish the adult thymus. Therefore, RAG-1+ early lymphoid progenitors (RAG-1+ ELP), and CD62L/L-selectin+ progenitors (LSP), as well as c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb820e7f3eb062db1efcbc71a1c5ad65
https://doi.org/10.4049/jimmunol.177.5.2880
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