Zobrazeno 1 - 10
of 15
pro vyhledávání: '"S Scott Perry"'
Autor:
Jessica Wagner, Stephen Gottschalk, Giedre Krenciute, Jinghui Zhang, Shannon Lange, Jason Chiang, Liqing Tian, Deanna Langfitt, Peter Vogel, Heather Sheppard, Timothy I Shaw, Jorge Ibanez, Selene C Koo, Elizabeth Wickman, Meifen Lu, Matthew Bell, S Scott Perry, Raghuvaran Shanmugam
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 11 (2024)
Background Oncofetal splice variants of extracellular matrix (ECM) proteins present a unique group of target antigens for the immunotherapy of pediatric cancers. However, limited data is available if these splice variants can be targeted with T cells
Externí odkaz:
https://doaj.org/article/8507f7b85407469dbd101d8fe85f0108
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251473 (2021)
During influenza A virus (IAV) entry, the hemagglutinin (HA) protein is triggered by endosomal low pH to undergo irreversible structural changes that mediate membrane fusion. HA proteins from different isolates vary in the pH at which they become act
Externí odkaz:
https://doaj.org/article/fd5ce1bbbc764df4badfa0592590b8cf
Autor:
Jean-Yves Métais, Phillip A. Doerfler, Thiyagaraj Mayuranathan, Daniel E. Bauer, Stephanie C. Fowler, Matthew M. Hsieh, Varun Katta, Sagar Keriwala, Cicera R. Lazzarotto, Kevin Luk, Michael D. Neel, S. Scott Perry, Samuel T. Peters, Shaina N. Porter, Byoung Y. Ryu, Akshay Sharma, Devlin Shea, John F. Tisdale, Naoya Uchida, Scot A. Wolfe, Kaitly J. Woodard, Yuxuan Wu, Yu Yao, Jing Zeng, Shondra Pruett-Miller, Shengdar Q. Tsai, Mitchell J. Weiss
Publikováno v:
Blood Advances, Vol 3, Iss 21, Pp 3379-3392 (2019)
Abstract: Induction of fetal hemoglobin (HbF) via clustered regularly interspaced short palindromic repeats/Cas9–mediated disruption of DNA regulatory elements that repress γ-globin gene (HBG1 and HBG2) expression is a promising therapeutic strate
Externí odkaz:
https://doaj.org/article/d8bdc8c4db524cf3ab90d0385b570174
Autor:
Jing Zeng, Byoung Y. Ryu, Kaitly J. Woodard, Stephanie Fowler, John F. Tisdale, Shengdar Q. Tsai, Jean-Yves Metais, Shondra M. Pruett-Miller, Cicera R. Lazzarotto, Yu Yao, Kevin Luk, Yuxuan Wu, Sagar Keriwala, Michael D. Neel, Daniel E. Bauer, Samuel T. Peters, S. Scott Perry, Scot A. Wolfe, Shaina N. Porter, Mitchell J. Weiss, Thiyagaraj Mayuranathan, Varun Katta, Naoya Uchida, Akshay Sharma, Matthew M. Hsieh, Devlin Shea, Phillip A. Doerfler
Publikováno v:
Blood Advances. 3:3379-3392
Induction of fetal hemoglobin (HbF) via clustered regularly interspaced short palindromic repeats/Cas9–mediated disruption of DNA regulatory elements that repress γ-globin gene (HBG1 and HBG2) expression is a promising therapeutic strategy for sic
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 5, p e0251473 (2021)
PLoS ONE, Vol 16, Iss 5, p e0251473 (2021)
During influenza A virus (IAV) entry, the hemagglutinin (HA) protein is triggered by endosomal low pH to undergo irreversible structural changes that mediate membrane fusion. HA proteins from different isolates vary in the pH at which they become act
Publikováno v:
Cell Transplantation, Vol 8 (1999)
Cyclosporin A (Cy A) has been reported to both stimulate and inhibit bone marrow colony assays in a dose-dependent manner. The observation that anti-γ-IFN antibodies stimulate hematopoiesis to the same degree as Cy A has led several groups to propos
Externí odkaz:
https://doaj.org/article/bfca0905702d4f6b8b3ec3c8cec44887
Autor:
Thiyagaraj Mayuranathan, Sagar Keriwala, Varun Katta, Kaitly J. Woodard, Stephanie Fowler, Mitchell J. Weiss, Jing Zeng, Yuxuan Wu, Yu Yao, S. Scott Perry, Kevin Luk, Samuel T. Peters, John F. Tisdale, Michael D. Neel, Cicera R. Lazzarotto, Byoung Y. Ryu, Jean-Yves Metais, Shengdar Q. Tsai, Naoya Uchida, Phillip A. Doerfler, Daniel E. Bauer, Matthew M. Hsieh, Devlin Shea, Akshay Sharma, Scot A. Wolfe, Shaina N. Porter, Shondra M. Pruett-Miller
Publikováno v:
Blood. 134:2066-2066
Induction of fetal hemoglobin (HbF, α2γ2) via genome editing-mediated disruption of DNA regulatory elements that repress expression of γ-globin genes (HBG1 and HBG2) is a promising therapeutic strategy for b-hemoglobinopathies including sickle cel
Autor:
Lei Nie, Xiao Hong Sun, Ying Zhao, Paul W. Kincade, Michael A. Farrar, S. Scott Perry, Jiaxue Huang
Publikováno v:
Molecular and Cellular Biology. 28:2078-2090
Notch signaling pathways exert diverse biological effects depending on the cellular context where Notch receptors are activated. How Notch signaling is integrated with environmental cues is a central issue. Here, we show that Notch activation acceler
Publikováno v:
Blood. 110:2351-2360
E-proteins are widely expressed basic helix-loop-helix (HLH) transcription factors that regulate differentiation in many cell lineages, including lymphoid, muscle, and neuronal cells. E-protein function is controlled by HLH inhibitors such as Id and
Autor:
Rosana Pelayo, Karla P. Garrett, Paul W. Kincade, Xiao Hong Sun, Xinrong Chen, S. Scott Perry, Barbara L. Kee, Robert S. Welner
Publikováno v:
Blood. 109:4825-4931
Interferon-producing killer dendritic cells (IKDCs) have only recently been described and they share some properties with plasmacytoid dendritic cells (pDCs). We now show that they can arise from some of the same progenitors. However, IKDCs expressed