Zobrazeno 1 - 10 of 688 pro vyhledávání: '"S Sauter"'
2
Akademický článek
Impact of Extraosseous Extramedullary Disease on Outcomes of Patients with Relapsed-Refractory Multiple Myeloma receiving Standard-of-Care Chimeric Antigen Receptor T-Cell Therapy
Autor: Danai Dima, Al-Ola Abdallah, James A. Davis, Hussein Awada, Utkarsh Goel, Aliya Rashid, Shaun DeJarnette, Faiz Anwer, Leyla Shune, Shahzad Raza, Zahra Mahmoudjafari, Louis Williams, Beth Faiman, Joseph P. McGuirk, Craig S. Sauter, Nausheen Ahmed, Jack Khouri, Hamza Hashmi
Publikováno v: Blood Cancer Journal, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract The presence of extramedullary disease (EMD) has been associated with poor outcomes in patients with relapsed-refractory multiple myeloma (RRMM). Herein, we report the outcomes of RRMM patients who were treated with standard-of-care (SOC) ch
Externí odkaz: https://doaj.org/article/4d4e0e6e0fe64208a7cce810ec77ca4d
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3
Akademický článek
Anti-CD19 chimeric antigen receptor T-cell therapy has less efficacy in Richter transformation than in de novo large B-cell lymphoma and transformed low-grade B-cell lymphoma
Autor: Ohad Benjamini, Shalev Fried, Roni Shouval, Jessica R. Flynn, Ofrat Beyar-Katz, Lori A Leslie, Tsilla Zucherman, Ronit Yerushalmi, Noga Shem-Tov, Maria Lia Palomba, Ivetta Danylesko, Inbal Sdayoor, Hila Malka, Orit Itzhaki, Hyung Suh, Sean M. Devlin, Ronit Marcus, Parastoo B Dahi, Elad Jacoby, Gunjan L Shah, Craig S Sauter, Andrew Ip, Miguel-Angel Perales, Arnon Nagler, Avichai Shimoni, Michael Scordo, Abraham Avigdor
Publikováno v: Haematologica, Vol 999, Iss 1 (2024)
The activity of anti-CD19 CAR T cell therapy in chronic lymphocytic leukemia (CLL) with Richter's transformation (RT) to aggressive large B cell lymphoma (LBCL) is largely unknown. In a multicenter retrospective study, we report the safety and effica
Externí odkaz: https://doaj.org/article/446c107a98b1415f962e7e3be018edfa
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4
Akademický článek
Pathogenesis and outcome of VA1 astrovirus infection in the human brain are defined by disruption of neural functions and imbalanced host immune responses.
Autor: Olga A Maximova, Melodie L Weller, Tammy Krogmann, Daniel E Sturdevant, Stacy Ricklefs, Kimmo Virtaneva, Craig Martens, Kurt Wollenberg, Mahnaz Minai, Ian N Moore, Craig S Sauter, Juliet N Barker, W Ian Lipkin, Danielle Seilhean, Avindra Nath, Jeffrey I Cohen
Publikováno v: PLoS Pathogens, Vol 19, Iss 8, p e1011544 (2023)
Astroviruses (AstVs) can cause of severe infection of the central nervous system (CNS) in immunocompromised individuals. Here, we identified a human AstV of the VA1 genotype, HAstV-NIH, as the cause of fatal encephalitis in an immunocompromised adult
Externí odkaz: https://doaj.org/article/bb23eb1b94ac407f968c090e9fa6efa1
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5
Akademický článek
Third-party cytomegalovirus-specific T cells improved survival in refractory cytomegalovirus viremia after hematopoietic transplant
Autor: Susan E. Prockop, Aisha Hasan, Ekaterina Doubrovina, Parastoo B. Dahi, Irene Rodriguez-Sanchez, Michael Curry, Audrey Mauguen, Genovefa A. Papanicolaou, Yiqi Su, JinJuan Yao, Maria Arcila, Farid Boulad, Hugo Castro-Malaspina, Christina Cho, Kevin J. Curran, Sergio Giralt, Nancy A. Kernan, Guenther Koehne, Ann Jakubowski, Esperanza Papadopoulos, Miguel-Angel Perales, Ioannis Politikos, Keith Price, Annamalai Selvakumar, Craig S. Sauter, Roni Tamari, Teresa Vizconde, James W. Young, Richard J. O’Reilly
Publikováno v: The Journal of Clinical Investigation, Vol 133, Iss 10 (2023)
Background Refractory CMV viremia and disease are associated with significant morbidity and mortality in recipients of hematopoietic stem cell transplant (HCT).Methods In phase I/II trials, we treated 67 subjects for CMV viremia or disease arising af
Externí odkaz: https://doaj.org/article/c8bff7f8a061422b8ccb6a5d37b43f5a
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6
Open-label pilot study of romiplostim for thrombocytopenia after autologous hematopoietic cell transplantation
Autor: Michael Scordo, Leah J. Gilbert, Danielle M. Hanley, Jessica R. Flynn, Sean M. Devlin, Linh K. Nguyen, Josel D. Ruiz, Gunjan L. Shah, Craig S. Sauter, David J. Chung, Heather J. Landau, Oscar B. Lahoud, Richard J. Lin, Parastoo B. Dahi, Miguel-Angel Perales, Sergio A. Giralt, Gerald A. Soff
Publikováno v: Blood Advances. 7:1536-1544
There are no standard treatments to prevent or hasten the recovery from severe conditioning-regimen–induced thrombocytopenia occurring after autologous hematopoietic cell transplantation (auto-HCT). We conducted an open-label, single-arm pilot stud
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e244dffe40a0b1da09124d3c7ed78c3
https://doi.org/10.1182/bloodadvances.2022007838
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9
Dynamic EASIX scores closely predict nonrelapse mortality after allogeneic hematopoietic cell transplantation
Autor: Mariam T. Nawas, Miriam Sanchez-Escamilla, Sean M. Devlin, Molly A. Maloy, Josel D. Ruiz, Craig S. Sauter, Sergio A. Giralt, Miguel-Angel Perales, Michael Scordo
Publikováno v: Blood Advances. 6:5898-5907
Endothelial activation and stress index (EASIX) predicts nonrelapse mortality (NRM) when assessed before hematopoietic cell transplantation (HCT). We sought to determine whether changes in EASIX after HCT may be an informative marker of NRM. We evalu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc76cfd079ebe9feaa3ad0dc27dd8a43
https://doi.org/10.1182/bloodadvances.2022007381
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