Zobrazeno 1 - 10
of 301
pro vyhledávání: '"S Sagoo"'
Publikováno v:
BMJ Open Ophthalmology, Vol 9, Iss 1 (2024)
Background Large genomic databases enable genetic evaluation in terms of haploinsufficiency and prevalence of missense and synonymous variants. We explored these parameters in ocular tumour-associated genes.Methods A curated list of ocular tumour-ass
Externí odkaz:
https://doaj.org/article/0aad19f4d25d4946acfc7631e75c858b
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Millions of people require custom ocular prostheses due to eye loss or congenital defects. The current fully manual manufacturing processes used by highly skilled ocularists are time-consuming with varying quality. Additive manufacturing tec
Externí odkaz:
https://doaj.org/article/78c550ebba854eda905c5a50d6ed79db
Autor:
Andrew L. Chen, BS, Navraj S. Sagoo, MD, Christopher Vannabouathong, MS, Yashas Reddy, BS, Sathvik Deme, BS, Sahiti Patibandla, BA, Peter G. Passias, MD, Shaleen Vira, MD
Publikováno v:
North American Spine Society Journal, Vol 17, Iss , Pp 100317- (2024)
Background: The treatment of spine metastases continues to pose a significant clinical challenge, requiring the integration of multiple therapeutic modalities to address the multifactorial aspects of this disease process. Radiofrequency ablation (RFA
Externí odkaz:
https://doaj.org/article/9dfab2c79bbc437b8bdddcde12df6476
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract The UK NHS Women’s National Breast Screening programme aims to detect breast cancer early. The reference standard approach requires mammograms to be independently double-read by qualified radiology staff. If two readers disagree, arbitrati
Externí odkaz:
https://doaj.org/article/de2cee4bcf3844dba9c4d112b49f2bbd
Autor:
Lyndon da Cruz, Taha Soomro, Odysseas Georgiadis, Britta Nommiste, Mandeep S. Sagoo, Peter Coffey
Publikováno v:
Diagnostics, Vol 14, Iss 10, p 1005 (2024)
(1) Background: We reviewed a stem cell-derived therapeutic strategy for advanced neovascular age-related macular degeneration (nAMD) using a human embryonic stem cell-derived retinal pigment epithelium (hESC-RPE) monolayer delivered on a coated, syn
Externí odkaz:
https://doaj.org/article/d064f03720ec4630bb31877dce881fc0
Autor:
Hongorzul Davaapil, Jack Hopkins, Nadia Bonnin, Vasiliki Papadaki, Alex Leung, Hirofumi Kosuge, Takumi Tashima, Makoto Nakakido, Ryohei Sekido, Kouhei Tsumoto, Mandeep S. Sagoo, Shin-Ichi Ohnuma
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: Proline/arginine-rich end leucine-rich repeat protein (PRELP), is a small secreted proteoglycan expressed by pericytes and vascular smooth muscle cells surrounding the brain vasculature of adult mouse.Methods: We utilised a Prelp knocko
Externí odkaz:
https://doaj.org/article/bfc8b0a0b800407591f92ad772143d20
Autor:
Liz McKechnie, Bethan Johnson, Jonathan Sutcliffe, Elizabeth Lawson, Hemma Chauhan, Gurdeep S Sagoo, Anna Littlejohns, Gary Latchford, Emile Crouzen, Waaka Moni-Nwinia, Douglas McConachie, John G McElwaine, Fiona Metcalfe, Rebecca Mernenko, Victoria Tricklebank
Publikováno v:
World Journal of Pediatric Surgery, Vol 6, Iss 3 (2023)
Objectives Patient experience is directly related to health outcomes, and parental experience can be used as a proxy for this in neonatal care. This project was designed to assess parental experience of neonatal surgical care to inform future service
Externí odkaz:
https://doaj.org/article/6cef74f3a131409982965cf14462c47f
Autor:
Oliver Coen, Pippa Corrie, Helen Marshall, Ruth Plummer, Christian Ottensmeier, Jane Hook, Sue Bell, Gurdeep S. Sagoo, David Meads, Janine Bestall, Galina Velikova, Ferdia A. Gallagher, Alexandra Smith, Helen Howard, Ellen Mason, Eszter Katona, Shobha Silva, Michelle Collinson, Simon Rodwell, Sarah Danson
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Immunotherapy is revolutionising the treatment of patients diagnosed with melanoma and other cancers. The first immune checkpoint inhibitor, ipilimumab (targeting cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4)), showed a sur
Externí odkaz:
https://doaj.org/article/94e82f3219214bb495cb4463d0ad4aed
Autor:
Adam Jameson, Beth Fylan, Greg C. Bristow, Gurdeep S. Sagoo, Caroline Dalton, Alastair Cardno, Jaspreet Sohal, Samantha L. McLean
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
In psychiatry, the selection of antipsychotics and antidepressants is generally led by a trial-and-error approach. The prescribing of these medications is complicated by sub-optimal efficacy and high rates of adverse drug reactions (ADRs). These both
Externí odkaz:
https://doaj.org/article/0b71a8354b7b4fa8901fd09fc9ba8e8c
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Ninety-five percent of the population are estimated to carry at least one genetic variant that is discordant with at least one medication. Pharmacogenomic (PGx) testing has the potential to identify patients with genetic variants that puts them at ri
Externí odkaz:
https://doaj.org/article/93db146844fc4eeaa6d1fca60599f06a